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  1. Artikel ; Online: Medicinal cannabis: new challenges for the anesthesiologist.

    Saffier, Igor P / Palmeira, Claudia C A

    Brazilian journal of anesthesiology (Elsevier)

    2021  Band 71, Heft 3, Seite(n) 306–307

    Mesh-Begriff(e) Anesthesiologists ; Humans ; Medical Marijuana
    Chemische Substanzen Medical Marijuana
    Sprache Englisch
    Erscheinungsdatum 2021-04-27
    Erscheinungsland Brazil
    Dokumenttyp Letter
    ISSN 2352-2291
    ISSN (online) 2352-2291
    DOI 10.1016/j.bjane.2021.02.056
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Intraoperative use of methadone improves control of postoperative pain in morbidly obese patients

    Machado FC / Palmeira CCA / Torres JNL / Vieira JE / Ashmawi HA

    Journal of Pain Research, Vol Volume 11, Pp 2123-

    a randomized controlled study

    2018  Band 2129

    Abstract: Felipe Chiodini Machado, Claudia Carneiro de Araújo Palmeira, João Nathanael Lima Torres, Joaquim Edson Vieira, Hazem Adel Ashmawi Anesthesiology Department, hcFMUsP, Universidade de São Paulo, São Paulo, Brazil Objectives: Surgical patients still ... ...

    Abstract Felipe Chiodini Machado, Claudia Carneiro de Araújo Palmeira, João Nathanael Lima Torres, Joaquim Edson Vieira, Hazem Adel Ashmawi Anesthesiology Department, hcFMUsP, Universidade de São Paulo, São Paulo, Brazil Objectives: Surgical patients still commonly experience postoperative pain. With the increasing prevalence of obesity, there is a growing demand for surgical procedures by this population. Intraoperative use of methadone has not been well assessed in this population. Materials and methods: Patients with a body mass index of 35 kg/m2 or more undergoing bariatric surgery were randomly assigned to receive either fentanyl (group F) or methadone (group M) in anesthesia induction and maintenance. The primary outcome was morphine consumption during the first 24 hours after surgery through a patient-controlled analgesia device. Secondary outcomes were pain scores at rest and while coughing, opioid related side effects, and patient satisfaction. The patients were also evaluated 3 months after surgery for the presence of pain, dysesthesia, or paresthesia at surgical site. Results: Postoperative morphine consumption was significantly higher for patients receiving fentanyl than methadone during the postoperative period at 2 hours (mean difference [MD] 6.4 mg; 95% CI 3.1–9.6; P<0.001), 2–6 hours (MD 11.4 mg; 95% CI 6.5–16.2; P<0.001), 6–24 hours (MD 10.4 mg; 95% CI 5.0–15.7; P<0.001), and 24–48 hours (MD 14.5 mg; 95% CI 3.9–25.1; P=0.01). Patients from group F had higher pain scores until 24 hours postoperatively, higher incidence of nausea and vomiting, lower satisfaction, and more evoked pain at surgical scar at the 3-month postoperative evaluation than group M. Conclusion: Intraoperative methadone can safely lower postoperative opioid consumption and improve postoperative pain scores compared with fentanyl in morbidly obese patients. Keywords: postoperative pain, bariatric surgery, acute pain, postoperative pain, methadone
    Schlagwörter Methadone ; Bariatric surgery ; Acute pain ; Postoperative pain ; Medicine (General) ; R5-920
    Sprache Englisch
    Erscheinungsdatum 2018-10-01T00:00:00Z
    Verlag Dove Medical Press
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  3. Artikel ; Online: Cannabinoid products for pain management: recommendations from the São Paulo State Society of Anesthesiology.

    de Barros, Guilherme Antonio Moreira / Pos, Alexandre Mio / Sousa, Ângela Maria / Pereira, Carla Leal / Nobre, Cecília Daniele de Azevedo / Palmeira, Cláudia Carneiro de Araújo / Caruy, Cristina Aparecida Arrivabene / Munhoz, Derli Conceição / Kraychete, Durval Campos / Avelar, Esthael Cristina Querido / Fukushima, Fernanda Bono / Garcia, João Batista Santos / Torres, João Nathanael Lima / Rodrigues, Karenthan de Abreu / Palladini, Mariana / Neto, Olympio de Hollanda Chacon / Carmona, Maria José Carvalho

    Brazilian journal of anesthesiology (Elsevier)

    2024  , Seite(n) 844513

    Abstract: There is growing interest in using cannabinoids across various clinical scenarios, including pain medicine, leading to the disregard of regulatory protocols in some countries. Legislation has been implemented in Brazil, specifically in the state of São ... ...

    Abstract There is growing interest in using cannabinoids across various clinical scenarios, including pain medicine, leading to the disregard of regulatory protocols in some countries. Legislation has been implemented in Brazil, specifically in the state of São Paulo, permitting the distribution of cannabinoid products by health authorities for clinical purposes, free of charge for patients, upon professional prescription. Thus, it is imperative to assess the existing evidence regarding the efficacy and safety of these products in pain management. In light of this, the São Paulo State Society of Anesthesiology (SAESP) established a task force to conduct a narrative review on the topic using the Delphi method, requiring a minimum agreement of 60% among panelists. The study concluded that cannabinoid products could potentially serve as adjuncts in pain management but stressed the importance of judicious prescription. Nevertheless, this review advises against their use for acute pain and cancer-related pain. In other clinical scenarios, established treatments should take precedence, particularly when clinical protocols are available, such as in neuropathic pain. Only patients exhibiting poor therapeutic responses to established protocols or demonstrating intolerance to recommended management may be considered as potential candidates for cannabinoids, which should be prescribed by physicians experienced in handling these substances. Special attention should be given to individual patient characteristics and the likelihood of drug interactions.
    Sprache Englisch
    Erscheinungsdatum 2024-05-11
    Erscheinungsland Brazil
    Dokumenttyp Journal Article ; Review
    ISSN 2352-2291
    ISSN (online) 2352-2291
    DOI 10.1016/j.bjane.2024.844513
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel: Intraoperative use of methadone improves control of postoperative pain in morbidly obese patients: a randomized controlled study.

    Machado, Felipe Chiodini / Palmeira, Claudia Carneiro de Araújo / Torres, João Nathanael Lima / Vieira, Joaquim Edson / Ashmawi, Hazem Adel

    Journal of pain research

    2018  Band 11, Seite(n) 2123–2129

    Abstract: Objectives: Surgical patients still commonly experience postoperative pain. With the increasing prevalence of obesity, there is a growing demand for surgical procedures by this population. Intraoperative use of methadone has not been well assessed in ... ...

    Abstract Objectives: Surgical patients still commonly experience postoperative pain. With the increasing prevalence of obesity, there is a growing demand for surgical procedures by this population. Intraoperative use of methadone has not been well assessed in this population.
    Materials and methods: Patients with a body mass index of 35 kg/m
    Results: Postoperative morphine consumption was significantly higher for patients receiving fentanyl than methadone during the postoperative period at 2 hours (mean difference [MD] 6.4 mg; 95% CI 3.1-9.6;
    Conclusion: Intraoperative methadone can safely lower postoperative opioid consumption and improve postoperative pain scores compared with fentanyl in morbidly obese patients.
    Sprache Englisch
    Erscheinungsdatum 2018-10-02
    Erscheinungsland New Zealand
    Dokumenttyp Journal Article
    ZDB-ID 2495284-9
    ISSN 1178-7090
    ISSN 1178-7090
    DOI 10.2147/JPR.S172235
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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