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  1. Buch ; Online ; E-Book: Delirium

    Hughes, Christopher G. / Pandharipande, Pratik / Ely, Eugene Wesley

    acute brain dysfunction in the critically ill

    2020  

    Verfasserangabe Christopher G. Hughes, Pratik P. Pandharipande, E. Wesley Ely editors
    Schlagwörter Intensive / Critical Care Medicine ; Anesthesiology ; Critical care medicine
    Thema/Rubrik (Code) 616.028
    Sprache Englisch
    Umfang 1 Online-Ressource (xiii, 237 Seiten), Illustrationen, Diagramme
    Verlag Springer
    Erscheinungsort Cham
    Erscheinungsland Schweiz
    Dokumenttyp Buch ; Online ; E-Book
    Bemerkung Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT030640369
    ISBN 978-3-030-25751-4 ; 9783030257507 ; 3-030-25751-7 ; 3030257509
    DOI 10.1007/978-3-030-25751-4
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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  2. Buch: Creating and implementing the 2013 ICU pain, agitation, and delirium guidelines for adult ICU patients

    Barr, Juliana / Pandharipande, Pratik

    (Critical care medicine ; 41,9, Suppl.)

    2013  

    Verfasserangabe guest ed.: Juliana Barr and Pratik P. Pandharipande
    Serientitel Critical care medicine ; 41,9, Suppl.
    Überordnung
    Sprache Englisch
    Umfang S145 S.
    Verlag Wolters Kluwer Health/Lippincott Williams & Wilkins
    Erscheinungsort Hagerstown, MD
    Erscheinungsland Vereinigte Staaten
    Dokumenttyp Buch
    HBZ-ID HT017797674
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  3. Buch: Sedation and analgesia in the ICU

    Pandharipande, Pratik

    pharmacology, protocolization, and clinical consequences

    (Critical care clinics ; 25,3)

    2009  

    Verfasserangabe guest ed. Pratik Pandharipande
    Serientitel Critical care clinics ; 25,3
    Überordnung
    Sprache Englisch
    Umfang XVI S., S. 432 - 635 : Ill., graph. Darst.
    Verlag Saunders
    Erscheinungsort Philadelphia u.a.
    Erscheinungsland Vereinigte Staaten
    Dokumenttyp Buch
    HBZ-ID HT016033323
    ISBN 1-4377-1203-7 ; 978-1-4377-1203-2
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  4. Artikel ; Online: Early mobilisation during critical illness: good for the body and brain.

    Girard, Timothy D / Pandharipande, Pratik P

    The Lancet. Respiratory medicine

    2023  Band 11, Heft 6, Seite(n) 500–502

    Mesh-Begriff(e) Humans ; Early Ambulation ; Critical Illness/therapy ; Brain ; Intensive Care Units
    Sprache Englisch
    Erscheinungsdatum 2023-01-25
    Erscheinungsland England
    Dokumenttyp Journal Article ; Comment
    ZDB-ID 2686754-0
    ISSN 2213-2619 ; 2213-2600
    ISSN (online) 2213-2619
    ISSN 2213-2600
    DOI 10.1016/S2213-2600(23)00011-5
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Do Our Sedation Practices Contribute to Increased Mortality in Coronavirus Disease 2019-Related Acute Respiratory Distress Syndrome?

    Devlin, John W / Pandharipande, Pratik P

    Critical care medicine

    2021  Band 49, Heft 9, Seite(n) 1579–1582

    Mesh-Begriff(e) COVID-19 ; Humans ; Respiration, Artificial ; Respiratory Distress Syndrome ; SARS-CoV-2
    Sprache Englisch
    Erscheinungsdatum 2021-05-12
    Erscheinungsland United States
    Dokumenttyp Editorial ; Comment
    ZDB-ID 197890-1
    ISSN 1530-0293 ; 0090-3493
    ISSN (online) 1530-0293
    ISSN 0090-3493
    DOI 10.1097/CCM.0000000000005094
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Buch: Sedation and analgesia in the ICU

    Pandharipande, Pratik / Ely, Eugene Wesley

    pharmacology, protocolization, and clinical consequences

    (Anesthesiology clinics ; 29,4)

    2011  

    Verfasserangabe guest ed. Pratik P. Pandharipande ; E. Wesley Ely
    Serientitel Anesthesiology clinics ; 29,4
    Überordnung
    Sprache Englisch
    Umfang XVI S., S. 567 - 773 : Ill.
    Verlag Saunders an imprint of Elsevier
    Erscheinungsort Philadelphia, PA
    Erscheinungsland Vereinigte Staaten
    Dokumenttyp Buch
    HBZ-ID HT017086548
    ISBN 978-1-4557-3360-6 ; 1-4557-3360-1
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  7. Artikel ; Online: Baseline Vulnerabilities May Play a Larger Role than Depth of Anesthesia or Sedation in Postoperative Delirium.

    Pandharipande, Pratik P / Whitlock, Elizabeth L / Hughes, Christopher G

    Anesthesiology

    2021  Band 135, Heft 6, Seite(n) 940–942

    Mesh-Begriff(e) Anesthesia ; Delirium ; Humans
    Sprache Englisch
    Erscheinungsdatum 2021-11-03
    Erscheinungsland United States
    Dokumenttyp Editorial ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 269-0
    ISSN 1528-1175 ; 0003-3022
    ISSN (online) 1528-1175
    ISSN 0003-3022
    DOI 10.1097/ALN.0000000000004039
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: The Conundrum of Pain, Opiate Use, and Delirium: Analgosedation or Analgesia-First Approach?

    Hayhurst, Christina J / Hughes, Christopher G / Pandharipande, Pratik P

    American journal of respiratory and critical care medicine

    2021  Band 204, Heft 5, Seite(n) 502–503

    Mesh-Begriff(e) Analgesia ; Delirium ; Humans ; Opiate Alkaloids ; Pain ; Pain Management
    Chemische Substanzen Opiate Alkaloids
    Sprache Englisch
    Erscheinungsdatum 2021-05-06
    Erscheinungsland United States
    Dokumenttyp Editorial ; Comment
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202104-0968ED
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Data-derived subtypes of delirium during critical illness.

    Potter, Kelly M / Kennedy, Jason N / Onyemekwu, Chukwudi / Prendergast, Niall T / Pandharipande, Pratik P / Ely, E Wesley / Seymour, Christopher / Girard, Timothy D

    EBioMedicine

    2024  Band 100, Seite(n) 104942

    Abstract: Background: To understand delirium heterogeneity, prior work relied on psychomotor symptoms or risk factors to identify subtypes. Data-driven approaches have used machine learning to identify biologically plausible, treatment-responsive subtypes of ... ...

    Abstract Background: To understand delirium heterogeneity, prior work relied on psychomotor symptoms or risk factors to identify subtypes. Data-driven approaches have used machine learning to identify biologically plausible, treatment-responsive subtypes of other acute illnesses but have not been used to examine delirium.
    Methods: We conducted a secondary analysis of a large, multicenter prospective cohort study involving adults in medical or surgical ICUs with respiratory failure or shock who experienced delirium per the Confusion Assessment Method for the ICU. We used data collected before delirium diagnosis in an unsupervised latent class model to identify delirium subtypes and then compared demographics, clinical characteristics, and outcomes between subtypes in the final model.
    Findings: The 731 patients who developed delirium during critical illness had a median age of 63 [IQR, 54-72] years, a median Sequential Organ Failure Assessment score of 8.0 [6.0-11.0] and 613 [83.4%] were mechanically ventilated at delirium identification. A four-class model best fit the data with 50% of patients in subtype (ST) 1, 18% in subtype 2, 17% in subtype 3, and 14% in subtype 4. Subtype 2-which had more shock and kidney impairment-had the highest mortality (33% [ST2] vs. 17% [ST1], 25% [ST3], and 17% [ST4], p = 0.003). Subtype 4-which received more benzodiazepines and opioids-had the longest duration of delirium (6 days [ST4] vs. 3 [ST1], 4 [ST2], and 3 days [ST3], p < 0.001) and coma (4 days [ST4] vs. 2 [ST1], 1 [ST2], and 2 days [ST3], p < 0.001). Each of the four data-derived delirium subtypes was observed within previously identified psychomotor and risk factor-based delirium subtypes. Clinically significant cognitive impairment affected all subtypes at follow-up, but its severity did not differ by subtype (3-month, p = 0.26; 12-month, p = 0.80).
    Interpretation: The four data-derived delirium subtypes identified in this study should now be validated in independent cohorts, examined for differential treatment effects in trials, and inform mechanistic work evaluating treatment targets.
    Funding: National Institutes of Health (T32HL007820, R01AG027472).
    Mesh-Begriff(e) Adult ; Humans ; Middle Aged ; Aged ; Delirium/diagnosis ; Delirium/etiology ; Prospective Studies ; Critical Illness ; Interleukin-1 Receptor-Like 1 Protein ; Cognitive Dysfunction/complications
    Chemische Substanzen Interleukin-1 Receptor-Like 1 Protein
    Sprache Englisch
    Erscheinungsdatum 2024-01-01
    Erscheinungsland Netherlands
    Dokumenttyp Multicenter Study ; Journal Article
    ZDB-ID 2851331-9
    ISSN 2352-3964
    ISSN (online) 2352-3964
    DOI 10.1016/j.ebiom.2023.104942
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel ; Online: In Response.

    Kingeter, Adam J / Pandharipande, Pratik P

    Anesthesia and analgesia

    2018  Band 129, Heft 2, Seite(n) e60

    Mesh-Begriff(e) Academic Medical Centers ; Awareness ; Intensive Care Units ; Surveys and Questionnaires
    Sprache Englisch
    Erscheinungsdatum 2018-10-09
    Erscheinungsland United States
    Dokumenttyp Letter ; Comment
    ZDB-ID 80032-6
    ISSN 1526-7598 ; 0003-2999
    ISSN (online) 1526-7598
    ISSN 0003-2999
    DOI 10.1213/ANE.0000000000003855
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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