Artikel ; Online: Circulating cell-free DNA release in vitro: kinetics, size profiling, and cancer-related gene methylation.
Journal of cellular physiology
2019 Band 234, Heft 8, Seite(n) 14079–14089
Abstract: Circulating cell-free DNA (ccfDNA) is a biological entity of great interest due to its potential as liquid biopsy biomaterial carrying clinically valuable information. To better understand its nature, we studied ccfDNA in vitro in two human cancer cell ... ...
| Abstract | Circulating cell-free DNA (ccfDNA) is a biological entity of great interest due to its potential as liquid biopsy biomaterial carrying clinically valuable information. To better understand its nature, we studied ccfDNA in vitro in two human cancer cell lines MCF-7 and HeLa. Normalized indexes of ccfDNA per cell population decreased over time of culture but were significantly elevated after exposure to IC |
|||||
|---|---|---|---|---|---|---|
| Mesh-Begriff(e) | Azacitidine/pharmacology ; Biomarkers, Tumor/genetics ; Cell-Free Nucleic Acids/drug effects ; Cell-Free Nucleic Acids/genetics ; DNA Methylation/genetics ; HeLa Cells ; Humans ; Kinetics ; MCF-7 Cells ; Neoplasms/genetics ; Neoplasms/pathology | |||||
| Chemische Substanzen | Biomarkers, Tumor ; Cell-Free Nucleic Acids ; Azacitidine (M801H13NRU) | |||||
| Sprache | Englisch | |||||
| Erscheinungsdatum | 2019-01-07 | |||||
| Erscheinungsland | United States | |||||
| Dokumenttyp | Journal Article ; Research Support, Non-U.S. Gov't | |||||
| ZDB-ID | 3116-1 | |||||
| ISSN | 1097-4652 ; 0021-9541 | |||||
| ISSN (online) | 1097-4652 | |||||
| ISSN | 0021-9541 | |||||
| DOI | 10.1002/jcp.28097 | |||||
| Signatur |
|
|||||
| Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
Volltext online
Zusatzmaterialien
Kategorien
Verfügbar in ZB MED Köln/Königswinter
| Uc I Zs.212: Hefte anzeigen | Standort: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
Über subito bestellen
Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.