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Artikel ; Online: Cortical astrocyte N-methyl-D-aspartate receptors influence whisker barrel activity and sensory discrimination in mice.

Ahmadpour, Noushin / Kantroo, Meher / Stobart, Michael J / Meza-Resillas, Jessica / Shabanipour, Shahin / Parra-Nuñez, Jesus / Salamovska, Tetiana / Muzaleva, Anna / O'Hara, Finnegan / Erickson, Dustin / Di Gaetano, Bruno / Carrion-Falgarona, Sofia / Weber, Bruno / Lamont, Alana / Lavine, Natalie E / Kauppinen, Tiina M / Jackson, Michael F / Stobart, Jillian L

Nature communications

2024  Band 15, Heft 1, Seite(n) 1571

Abstract: Astrocytes express ionotropic receptors, including N-methyl-D-aspartate receptors (NMDARs). However, the contribution of NMDARs to astrocyte-neuron interactions, particularly in vivo, has not been elucidated. Here we show that a knockdown approach to ... ...

Abstract Astrocytes express ionotropic receptors, including N-methyl-D-aspartate receptors (NMDARs). However, the contribution of NMDARs to astrocyte-neuron interactions, particularly in vivo, has not been elucidated. Here we show that a knockdown approach to selectively reduce NMDARs in mouse cortical astrocytes decreases astrocyte Ca
Mesh-Begriff(e) Mice ; Animals ; Astrocytes/metabolism ; Receptors, N-Methyl-D-Aspartate/metabolism ; Vibrissae/metabolism ; Neurons/metabolism ; Signal Transduction
Chemische Substanzen Receptors, N-Methyl-D-Aspartate
Sprache Englisch
Erscheinungsdatum 2024-02-21
Erscheinungsland England
Dokumenttyp Journal Article
ZDB-ID 2553671-0
ISSN 2041-1723 ; 2041-1723
ISSN (online) 2041-1723
ISSN 2041-1723
DOI 10.1038/s41467-024-45989-3
Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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