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  1. Artikel ; Online: Positive impact of lockdown on COVID-19 outbreak in Thailand.

    Dechsupa, Sinsuda / Assawakosri, Suvichada / Phakham, Suphattra / Honsawek, Sittisak

    Travel medicine and infectious disease

    2020  Band 36, Seite(n) 101802

    Mesh-Begriff(e) Betacoronavirus ; COVID-19 ; Centers for Disease Control and Prevention, U.S. ; China ; Coronavirus ; Coronavirus Infections/epidemiology ; Humans ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2 ; Thailand ; United States
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-06-20
    Erscheinungsland Netherlands
    Dokumenttyp Letter ; Comment
    ZDB-ID 2170891-5
    ISSN 1873-0442 ; 1477-8939
    ISSN (online) 1873-0442
    ISSN 1477-8939
    DOI 10.1016/j.tmaid.2020.101802
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Volltext online

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    Verfügbar in ZB MED Köln/Königswinter

    Zs.A 6236: Hefte anzeigen Standort:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  3. Artikel ; Online: Positive impact of lockdown on COVID-19 outbreak in Thailand

    Dechsupa, Sinsuda / Assawakosri, Suvichada / Phakham, Suphattra / Honsawek, Sittisak

    Travel Medicine and Infectious Disease

    2020  Band 36, Seite(n) 101802

    Schlagwörter Public Health, Environmental and Occupational Health ; Infectious Diseases ; covid19
    Sprache Englisch
    Verlag Elsevier BV
    Erscheinungsland us
    Dokumenttyp Artikel ; Online
    ZDB-ID 2170891-5
    ISSN 1873-0442 ; 1477-8939
    ISSN (online) 1873-0442
    ISSN 1477-8939
    DOI 10.1016/j.tmaid.2020.101802
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Volltext online

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    Verfügbar in ZB MED Köln/Königswinter

    Zs.A 6236: Hefte anzeigen Standort:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  4. Artikel ; Online: Cytokine Profiling and Intra-Articular Injection of Autologous Platelet-Rich Plasma in Knee Osteoarthritis.

    Riewruja, Kanyakorn / Phakham, Suphattra / Sompolpong, Patlapa / Reantragoon, Rangsima / Tanavalee, Aree / Ngarmukos, Srihatach / Udomsinprasert, Wanvisa / Suantawee, Tanyawan / Dechsupa, Sinsuda / Honsawek, Sittisak

    International journal of molecular sciences

    2022  Band 23, Heft 2

    Abstract: Osteoarthritis (OA) is a degenerative joint disease leading to joint pain and stiffness. Due to lack of effective treatments, physical and psychological disabilities caused by OA have a detrimental impact on the patient's quality of life. Emerging ... ...

    Abstract Osteoarthritis (OA) is a degenerative joint disease leading to joint pain and stiffness. Due to lack of effective treatments, physical and psychological disabilities caused by OA have a detrimental impact on the patient's quality of life. Emerging evidence suggests that intra-articular injection of platelet-rich plasma (PRP) may provide favorable results since PRP comprises not only a high level of platelets but also a huge amount of cytokines, chemokines, and growth factors. However, the precise mechanism and standardization method remain uncertain. This study aimed to examine cytokine profiling in both PRP and platelet-poor plasma (PPP) of knee OA patients and to determine the effects of PRP on OA chondrocytes and knee OA patients. PRP contained a wide variety of cytokines, chemokines, growth factors, and autologous intra-articular PRP injection resulted in favorable outcomes in knee OA patients. Significant increases in levels of IL-1, IL-2, IL-7, IL-8, IL-9, IL-12, TNF-α, IL-17, PDGF-BB, bFGF, and MIP-1β were detected in PRP compared to PPP (
    Mesh-Begriff(e) Aged ; Biomarkers ; Cell Movement ; Cell Proliferation ; Chondrocytes/metabolism ; Cytokines/metabolism ; Disease Management ; Disease Susceptibility ; Female ; Humans ; Inflammation Mediators ; Male ; Middle Aged ; Osteoarthritis, Knee/diagnosis ; Osteoarthritis, Knee/etiology ; Osteoarthritis, Knee/metabolism ; Osteoarthritis, Knee/therapy ; Platelet-Rich Plasma ; Treatment Outcome
    Chemische Substanzen Biomarkers ; Cytokines ; Inflammation Mediators
    Sprache Englisch
    Erscheinungsdatum 2022-01-14
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms23020890
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Two or four injections of platelet-rich plasma for osteoarthritic knee did not change synovial biomarkers but similarly improved clinical outcomes.

    Ngarmukos, Srihatach / Tanavalee, Chotetawan / Amarase, Chavarin / Phakham, Suphattra / Mingsiritham, Warayapa / Reantragoon, Rangsima / Leearamwat, Nitigorn / Kongkaew, Thidarat / Tharakhet, Kittipan / Honsawek, Sittisak / Dechsupa, Sinsuda / Tanavalee, Aree

    Scientific reports

    2021  Band 11, Heft 1, Seite(n) 23603

    Abstract: We compared two and four intra-articular injections of platelet-rich plasma (PRP) in terms of changes of synovial cytokines and clinical outcomes. One hundred twenty-five patients having knee osteoarthritis (OA) underwent PRP injections at a 6-week ... ...

    Abstract We compared two and four intra-articular injections of platelet-rich plasma (PRP) in terms of changes of synovial cytokines and clinical outcomes. One hundred twenty-five patients having knee osteoarthritis (OA) underwent PRP injections at a 6-week interval. Before each PRP injection, synovial fluid aspiration was collected for investigation. Patients were divided into two or four intra-articular PRP injections (group A and B, respectively). Changes in synovial biomarkers were compared with the baseline levels of both groups, and clinical outcomes were evaluated until one year. Ninety-four patients who had completed synovial fluid collection were included for final evaluation, 51 in group A and 43 in group B. There were no differences in mean age, gender, body mass index (BMI), and radiographic OA grading. The average platelet count and white blood cell count in PRP were 430,000/µL and 200/ µL, respectively. There were no changes of synovial inflammatory cytokines (IL-1β, IL-6, IA-17A, and TNF-alpha), anti-inflammatory cytokines (IL-4, IL-10, IL-13, and IL-1RA), and growth factors (TGF-B1, VEGF, PDGF-AA, and PDGF-BB) between baseline levels and six weeks in group A, and 18 weeks in group B. Both groups had significantly improved clinical outcomes from six weeks including visual analog scale (VAS), patient-reported outcome measures [PROMs; Western Ontario and McMaster Universities Osteoarthritis (WOMAC) Index and Short Form-12 (SF-12)], with a significant delayed improvement of performance-based measures [PBMs; time up and go (TUG), 5-time sit to stand test (5 × SST), and 3-min walk test (3-min WT)]. In conclusion, two- or four-PRP intra-articular injection at a 6-week interval for knee OA demonstrated no changes of synovial cytokines and growth factors but similarly improved clinical outcomes from 6 weeks until 1 year.
    Mesh-Begriff(e) Aged ; Biomarkers/metabolism ; Female ; Humans ; Injections, Intra-Articular ; Male ; Middle Aged ; Osteoarthritis, Knee/therapy ; Platelet-Rich Plasma ; Synovial Membrane/metabolism ; Treatment Outcome
    Chemische Substanzen Biomarkers
    Sprache Englisch
    Erscheinungsdatum 2021-12-08
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-021-03081-6
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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