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  1. Buch ; Online ; E-Book: Handbook of HER2-targeted agents in breast cancer

    Alvarez, Ricardo / Cortes, Javier / Falzon, Mary / Gianni, Luca / Harbeck, Nadia / Piccart, Martine

    2016  

    Verfasserangabe Ricardo H. Alvarez, Javier Cortés, Mary Falzon, Michael Gandy, Luca Gianni, Nadia Harbeck, Martine Piccart
    Schlagwörter Breast Neoplasms / drug therapy ; Breast Neoplasms / genetics ; Genes, erbB-2 ; Gene Targeting ; Breast cancer ; Cancer ; HER2 ; HER2-positive ; Oncology ; Pertuzumab ; Trastuzumab
    Thema/Rubrik (Code) 610
    Sprache Englisch
    Umfang 1 Online-Ressource (110 Seiten), Illustrationen
    Ausgabenhinweis Second edition
    Verlag Springer
    Erscheinungsort Cham
    Erscheinungsland Deutschland
    Dokumenttyp Buch ; Online ; E-Book
    Anmerkung Lizenzpflichtig
    Bemerkung Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019455877
    ISBN 978-3-319-28216-9 ; 9783319282145 ; 3-319-28216-6 ; 331928214X
    DOI 10.1007/978-3-319-28216-9
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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  2. Artikel ; Online: Molecular Imaging in Breast Cancer: Martine Piccart and Géraldine Gebhart Talk with David Mankoff About 2 Generations of Research.

    Gebhart, Géraldine / Piccart, Martine / Mankoff, David

    Journal of nuclear medicine : official publication, Society of Nuclear Medicine

    2024  

    Sprache Englisch
    Erscheinungsdatum 2024-02-08
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 80272-4
    ISSN 1535-5667 ; 0097-9058 ; 0161-5505 ; 0022-3123
    ISSN (online) 1535-5667
    ISSN 0097-9058 ; 0161-5505 ; 0022-3123
    DOI 10.2967/jnumed.124.267461
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Emerging treatments in HER2-positive advanced breast cancer: Keep raising the bar.

    Agostinetto, Elisa / Curigliano, Giuseppe / Piccart, Martine

    Cell reports. Medicine

    2024  , Seite(n) 101575

    Abstract: Patients with human epidermal receptor 2 (HER2)-positive breast cancer are experiencing a consistent shift toward better survival across the years, thanks to tremendous advancements in treatment strategies. The consistent improvements of outcomes set a ... ...

    Abstract Patients with human epidermal receptor 2 (HER2)-positive breast cancer are experiencing a consistent shift toward better survival across the years, thanks to tremendous advancements in treatment strategies. The consistent improvements of outcomes set a high bar for new drug development and the need to explore new ways to overcome resistance mechanisms. Emerging treatments in HER2-positive breast cancer aim to tackle the disease by acting on different targets, including not only HER2 (both at the extra- and intracellular level), but also HER3, PD-(L)1, CTLA4, NKG2A, AKT, PI3K, and, in triple-positive tumors, the estrogen receptors and the cyclin-dependent kinases 4/6. This review describes the evolving treatment landscape of HER2-positive breast cancer, from the current approved therapies to the future perspectives, with a focus on the new agents which are likely to get approved in the next future.
    Sprache Englisch
    Erscheinungsdatum 2024-05-10
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ISSN 2666-3791
    ISSN (online) 2666-3791
    DOI 10.1016/j.xcrm.2024.101575
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Buch: Triple negative breast cancer in focus

    Piccart-Gebhart, Martine J.

    from biology to novel therapeutics

    (Annals of oncology ; 23, Suppl. 6)

    2012  

    Titelvarianten Triple-negative breast cancer in focus
    Verfasserangabe guest ed.: M. Piccart
    Serientitel Annals of oncology ; 23, Suppl. 6
    Überordnung
    Sprache Englisch
    Umfang 65 S. : Ill., graph. Darst.
    Verlag Oxford Univ. Press
    Erscheinungsort Oxford
    Erscheinungsland Vereinigtes Königreich
    Dokumenttyp Buch
    HBZ-ID HT017437797
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  5. Buch: Breast cancer: progress and promise / 1 / guest ed. Martine J. Piccart-Gebhart ...

    Piccart-Gebhart, Martine J.

    (The oncologist ; 15, Suppl. 5)

    2010  

    Serientitel The oncologist ; 15, Suppl. 5
    Breast cancer ; progress and promise
    Überordnung Breast cancer ; progress and promise
    Sprache Englisch
    Umfang 65 S. : Ill., graph. Darst.
    Verlag AlphaMed Press
    Erscheinungsort Durham, NC
    Erscheinungsland Vereinigte Staaten
    Dokumenttyp Buch
    HBZ-ID HT016674036
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  6. Artikel ; Online: Systemic therapy for early-stage breast cancer: learning from the past to build the future.

    Agostinetto, Elisa / Gligorov, Joseph / Piccart, Martine

    Nature reviews. Clinical oncology

    2022  Band 19, Heft 12, Seite(n) 763–774

    Abstract: The treatment of breast cancer has improved dramatically over the past century, from a strictly surgical approach to a coordinated one, including local and systemic therapies. Systemic therapies for early-stage disease were initially tested against ... ...

    Abstract The treatment of breast cancer has improved dramatically over the past century, from a strictly surgical approach to a coordinated one, including local and systemic therapies. Systemic therapies for early-stage disease were initially tested against observation or placebo only in adjuvant trials. Subsequent clinical trials focusing on treatment 'fine-tuning' had a marked increase in cohort size, duration and costs, leading to a growing interest in the neoadjuvant setting in the past decade. Neoadjuvant trial designs have the advantages of enabling the direct evaluation of treatment effects on tumour diameter and offer unique translational research opportunities through the comparative analysis of tumour biology before, during and after treatment. Current technologies enabling the identification of better predictive biomarkers are shaping the new era of (neo)adjuvant trials. An urgent need exists to reinforce collaboration between the pharmaceutical industry and academia to share data and thus establish large databases of biomarker data coupled with patient outcomes that are easily accessible to the scientific community. In this Review, we summarize the evolution of (neo)adjuvant trials from the pre-genomic to the post-genomic era and provide critical insights into how neoadjuvant studies are currently designed, discussing the need for better end points and treatment strategies that are more personalized, including in the post-neoadjuvant setting.
    Mesh-Begriff(e) Humans ; Female ; Breast Neoplasms/pathology ; Neoadjuvant Therapy ; Chemotherapy, Adjuvant
    Sprache Englisch
    Erscheinungsdatum 2022-10-17
    Erscheinungsland England
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2491410-1
    ISSN 1759-4782 ; 1759-4774
    ISSN (online) 1759-4782
    ISSN 1759-4774
    DOI 10.1038/s41571-022-00687-1
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel: International research to address the challenges of metastatic breast cancer: the AURORA Program (BIG 14-01).

    Caballero, Carmela / Irrthum, Alexandre / Goulioti, Theodora / Cameron, David / Norton, Larry / Piccart, Martine

    NPJ breast cancer

    2023  Band 9, Heft 1, Seite(n) 42

    Sprache Englisch
    Erscheinungsdatum 2023-05-23
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 2374-4677
    ISSN 2374-4677
    DOI 10.1038/s41523-023-00548-9
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Buch ; Online: Breast Cancer Management and Molecular Medicine: Towards Tailored Approaches

    Piccart, Martine J. / Cardoso, Fatima / Hung, Chie-Mien / Solin, Lawrence J. / Wood, William C.

    2006  

    Verfasserangabe edited by Martine J. PiccartWilliam C. Wood, Chie-Mien Hung, Lawrence J. Solin et al
    Schlagwörter Gynecology ; Oncology ; Radiotherapy ; Surgery
    Sprache Englisch
    Verlag Springer-Verlag GmbH
    Erscheinungsort Berlin Heidelberg
    Dokumenttyp Buch ; Online
    HBZ-ID TT050387627
    ISBN 978-3-540-28265-5 ; 978-3-540-28266-2 ; 3-540-28265-3 ; 3-540-28266-1
    DOI 10.1007/978-3-540-28266-2
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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  9. Buch: Breast cancer: progress and promise

    Piccart-Gebhart, Martine J. / Hudis, Clifford A.

    (The oncologist : European edition ; 16, Suppl. 1)

    2011  

    Verfasserangabe guest ed. Martine J. Piccart-Gebhart and Clifford A. Hudis
    Serientitel The oncologist : European edition ; 16, Suppl. 1
    The oncologist
    The oncologist ; European edition
    Überordnung The oncologist
    The oncologist ; European edition
    Sprache Englisch
    Umfang 90 S. : Ill., graph. Darst.
    Verlag AlphaMed Press
    Erscheinungsort Durham, NC
    Erscheinungsland Vereinigte Staaten
    Dokumenttyp Buch
    HBZ-ID HT017050994
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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