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Article ; Online: Clinical Characteristics of Coronavirus Disease (COVID-19) in Mexican Children and Adolescents.

Flores-Alanis, Alejandro / Saldaña-Ahuactzi, Zeus / Parra-Ortega, Israel / López-Ramírez, Pablo / Salazar-García, Marcela / Alemán-García, Yolanda P / Cruz-Rangel, Armando / Moreno-Paredes, Alba / Diaz-Rojas, Adrián / Maldonado-Bernal, Carmen / Quevedo-Moran, Jessica / Luna-Pineda, Victor M

Viruses

2022  Volume 14, Issue 10

Abstract: Background: We analyzed the demographic, clinical, and diagnostic data of children and adolescents in Mexico, from the first case of coronavirus disease (COVID-19) to 28 February 2022.: Methods: Using the open databases of the Ministry of Health and ... ...

Abstract Background: We analyzed the demographic, clinical, and diagnostic data of children and adolescents in Mexico, from the first case of coronavirus disease (COVID-19) to 28 February 2022.
Methods: Using the open databases of the Ministry of Health and a tertiary pediatric hospital, we obtained demographic and clinical data from the beginning of the COVID-19 pandemic until 28 February 2022. In addition, quantitative reverse-transcription polymerase chain reaction outputs were used to determine the viral load, and structural protein-based serology was performed to evaluate IgG antibody levels.
Results: Of the total 437,832 children and adolescents with COVID-19, 1187 died. Of these patients, 1349 were admitted to the Hospital Infantil de Mexico Federico Gómez, and 11 died. Obesity, asthma, and immunosuppression were the main comorbidities, and fever, cough, and headache were the main symptoms. In this population, many patients have a low viral load and IgG antibody levels.
Conclusion: During the first 2 years of the COVID-19 pandemic in Mexico, children and adolescents had low incidence and mortality. They are a heterogeneous population, but many patients had comorbidities such as obesity, asthma, and immunosuppression; symptoms such as fever, cough, and headache; and low viral load and IgG antibodies.
MeSH term(s) Humans ; Adolescent ; Child ; Pandemics ; COVID-19/diagnosis ; COVID-19/epidemiology ; Cough ; Mexico/epidemiology ; SARS-CoV-2 ; Immunoglobulin G ; Fever ; Headache ; Obesity ; Asthma/epidemiology
Chemical Substances Immunoglobulin G
Language English
Publishing date 2022-09-30
Publishing country Switzerland
Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID 2516098-9
ISSN 1999-4915 ; 1999-4915
ISSN (online) 1999-4915
ISSN 1999-4915
DOI 10.3390/v14102162
Database MEDical Literature Analysis and Retrieval System OnLINE

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