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  1. Artikel ; Online: The relationship between the upper aerodigestive microbiome axis and head and neck cancers: it is time to bet on it?

    De Luca, Pietro / Radici, Marco / Camaioni, Angelo

    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

    2023  Band 280, Heft 9, Seite(n) 4299–4301

    Mesh-Begriff(e) Humans ; Head and Neck Neoplasms ; Laryngeal Neoplasms
    Sprache Englisch
    Erscheinungsdatum 2023-06-13
    Erscheinungsland Germany
    Dokumenttyp Letter ; Comment
    ZDB-ID 1017359-6
    ISSN 1434-4726 ; 0937-4477
    ISSN (online) 1434-4726
    ISSN 0937-4477
    DOI 10.1007/s00405-023-08037-2
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  2. Artikel ; Online: 3-D virtual reality surgery training to improve muscle memory and surgical skills in head and neck residents/young surgeons.

    De Luca, Pietro / Di Stadio, Arianna / Scarpa, Alfonso / Ricciardiello, Filippo / Viola, Pasquale / Radici, Marco / Camaioni, Angelo

    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

    2024  Band 281, Heft 5, Seite(n) 2767–2770

    Mesh-Begriff(e) Humans ; Virtual Reality ; Surgeons ; Muscles ; Clinical Competence ; Internship and Residency ; Computer Simulation ; Otolaryngology/education
    Sprache Englisch
    Erscheinungsdatum 2024-03-04
    Erscheinungsland Germany
    Dokumenttyp Letter
    ZDB-ID 1017359-6
    ISSN 1434-4726 ; 0937-4477
    ISSN (online) 1434-4726
    ISSN 0937-4477
    DOI 10.1007/s00405-024-08573-5
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  3. Artikel ; Online: First Extraction of Transversity from a Global Analysis of Electron-Proton and Proton-Proton Data.

    Radici, Marco / Bacchetta, Alessandro

    Physical review letters

    2018  Band 120, Heft 19, Seite(n) 192001

    Abstract: We present the first extraction of the transversity distribution in the framework of collinear factorization based on the global analysis of pion-pair production in deep-inelastic scattering and in proton-proton collisions with a transversely polarized ... ...

    Abstract We present the first extraction of the transversity distribution in the framework of collinear factorization based on the global analysis of pion-pair production in deep-inelastic scattering and in proton-proton collisions with a transversely polarized proton. The extraction relies on the knowledge of dihadron fragmentation functions, which are taken from the analysis of electron-positron annihilation data. For the first time, the transversity is extracted from a global analysis similar to what is usually done for the spin-averaged and helicity distributions. The knowledge of transversity is important for, among other things, detecting possible signals of new physics in high-precision low-energy experiments.
    Sprache Englisch
    Erscheinungsdatum 2018-05-11
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.120.192001
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  4. Artikel ; Online: Fitostimoline® in fibro-endoscopic and trans-nasal trans-speculum septoplasty as a beneficial tool to improve post-surgical outcome: Preliminary results of a case-control study.

    De Luca, Pietro / La Mantia, Ignazio / Gioacchini, Federico Maria / Re, Massimo / Radici, Marco / Camaioni, Angelo / Di Stadio, Arianna

    American journal of otolaryngology

    2023  Band 45, Heft 1, Seite(n) 104107

    Abstract: Objectives: Topic treatment can be useful to improve short and long-term nasal outcomes after nasal surgery, reducing discomfort and risk of synechia. This study aimed at evaluating the effect on clinical outcomes of nasal packaging using Fitostimoline® ...

    Abstract Objectives: Topic treatment can be useful to improve short and long-term nasal outcomes after nasal surgery, reducing discomfort and risk of synechia. This study aimed at evaluating the effect on clinical outcomes of nasal packaging using Fitostimoline® gauze in FESS and septoplasty.
    Methods: A case-control study on hospitalized patients was performed in a tertiary referral center. The control group included 20 patients treated with the standard surgical protocol for septoplasty and standard nasal packaging; treatment group included 21 patients underwent same surgical procedure but in whom the nasal tampon was wrapped with a gauze containing Fitostimoline® before being placed into the nose.
    Results: Patients in treatment group had better outcomes than control; nasal mucosa showed better healing - recovery of normal color- in those patients in whom we applied the Fitostimoline® gauze around tampons. Moreover, 100 % patients in the treatment group did not refer discomfort during at tampon removal versus 60 % subjects in the control group who referred pain, tension or tearing during the same action.
    Conclusion: Our results, although preliminary because of the small cohort of subjects included, suggest that the apposition of a gauze with Fitostimoline® after nasal surgery might improve the mucosal healing with consequent reduction of patients discomfort during the post-surgical period.
    Mesh-Begriff(e) Humans ; Case-Control Studies ; Nasal Septum/surgery ; Rhinoplasty/methods ; Endoscopy/adverse effects ; Surgical Instruments/adverse effects ; Treatment Outcome ; Nasal Obstruction/surgery
    Sprache Englisch
    Erscheinungsdatum 2023-11-03
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 604541-8
    ISSN 1532-818X ; 0196-0709
    ISSN (online) 1532-818X
    ISSN 0196-0709
    DOI 10.1016/j.amjoto.2023.104107
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  5. Artikel ; Online: Tissue expression of miR-449a as risk factor for occult neck metastasis in patients with cT3-T4 N0 laryngeal cancer. A pilot study.

    Ricciardiello, Filippo / Falco, Michela / Scarpa, Alfonso / Motta, Giovanni / Viola, Pasquale / Bocchetti, Marco / Caraglia, Michele / Alfieri, Nello / Oliva, Flavia / Tammaro, Chiara / Tortoriello, Giuseppe / Radici, Marco / Camaioni, Angelo / Misso, Gabriella / De Luca, Pietro

    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

    2024  

    Abstract: Objective: To explore the potential role of miR-449a as biomarker for laryngeal squamous cell carcinoma (LSCC), especially in the decision strategy of neck dissection (ND).: Methods: Each patient underwent total laryngectomy and bilateral ND (levels ... ...

    Abstract Objective: To explore the potential role of miR-449a as biomarker for laryngeal squamous cell carcinoma (LSCC), especially in the decision strategy of neck dissection (ND).
    Methods: Each patient underwent total laryngectomy and bilateral ND (levels II-IV); during surgery, tissue samples of around 1 × 0.5 cm were extracted from both healthy tissue adjacent to the tumor and the visibly affected tumor tissue. The extraction of total RNA, encompassing miRNA, was performed using a mirVana PARIS kit. To detect miR449a, cDNA was synthesized from 200 ng of RNA using a TaqMan miRNA reverse transcription kit.
    Results: The study group was formed of 66 patients (62 males, and 4 females) with LSCC, aged between 39 and 77 years (mean 60 + 14.56 yr). MiR-449a was up-regulated in twenty-eight tumors (42%), while it was down-regulated in 38 samples (58%). In the present study, there was a statistical relevance for miR-449a tissue expression for pN staging (p = 0.017), and PNI (p = 0.005). Eight tumors (12%) cN0 became pN + showing occult cervical lymph node metastases at the final histopathological examination, and all of these patients showed miR-449a downregulation.
    Conclusion: Super-selective ND (sparing the sub evels IIb and IV) might be the approach to cT3-T4 N0 LSCCs with upregulation of miR-449a; on the other hand, to ensure and effective control of occult neck metastases it would be appropriate to reserve elective ND (including sublevels IIb and IV) for cT3-T4 N0 LSCCs with miR-449a downregulation. Although promising, due to the small size of the cohort, the results of this work can be considered preliminary and need to be confirmed by prospective and larger studies.
    Sprache Englisch
    Erscheinungsdatum 2024-05-21
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 1017359-6
    ISSN 1434-4726 ; 0937-4477
    ISSN (online) 1434-4726
    ISSN 0937-4477
    DOI 10.1007/s00405-024-08743-5
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  6. Artikel ; Online: Prevention of withdrawal symptoms in alcoholic patients with head and neck cancer.

    Laus, Melissa / Trignani, Marianna / Crescenzi, Domenico / Radici, Marco / Croce, Adelchi

    Minerva chirurgica

    2020  Band 75, Heft 6, Seite(n) 430–435

    Abstract: Background: The role of alcohol abuse is common in the onset of cancer of the upper aerodigestive tract, especially that affecting the tongue, floor of the mouth, palatine tonsil and piriform sinus. The consequences of the abuse of alcohol immediately ... ...

    Abstract Background: The role of alcohol abuse is common in the onset of cancer of the upper aerodigestive tract, especially that affecting the tongue, floor of the mouth, palatine tonsil and piriform sinus. The consequences of the abuse of alcohol immediately after surgery in these patients are less known. But they are very important to achieve good final results.
    Methods: To try to understand the best treatment for withdrawal symptoms in a group of Italian patient with head and neck cancers, we administered a 10-item questionnaire. Subsequently, we decided to send the questionnaire to the main Italian centers of head and neck oncology using the platform of online surveys SurveyMonkey.
    Results: The results show clearly that it is not easy, within the Italian "latin" culture and lifestyle to correctly identify the alcoholic patient (patients in the last stage of the of the disease with a "behavioral dependency") and that the centers which address these problems mostly use a drug treatment, employing in particular two classes of drugs, associated or not with thiamine, with a varying quantity of other vitamins.
    Conclusions: It is important to know the early withdrawal syndrome to assess the ideal treatment. We propose a personal protocol to present this complication.
    Mesh-Begriff(e) Alcoholism/complications ; Alcoholism/diagnosis ; Alcoholism/epidemiology ; Antipsychotic Agents/therapeutic use ; Cancer Care Facilities/statistics & numerical data ; Cultural Characteristics ; Head and Neck Neoplasms/surgery ; Health Care Surveys/statistics & numerical data ; Humans ; Hypnotics and Sedatives/therapeutic use ; Italy ; Postoperative Complications/prevention & control ; Substance Withdrawal Syndrome/prevention & control ; Thiamine/therapeutic use ; Vitamin B Complex/therapeutic use ; Vitamins/therapeutic use
    Chemische Substanzen Antipsychotic Agents ; Hypnotics and Sedatives ; Vitamins ; Vitamin B Complex (12001-76-2) ; Thiamine (X66NSO3N35)
    Sprache Englisch
    Erscheinungsdatum 2020-08-06
    Erscheinungsland Italy
    Dokumenttyp Journal Article ; Multicenter Study
    ZDB-ID 123603-9
    ISSN 1827-1626 ; 0026-4733
    ISSN (online) 1827-1626
    ISSN 0026-4733
    DOI 10.23736/S0026-4733.20.08316-9
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  7. Artikel: Bilateral and Ipsilateral Central Neck Dissection in Total Thyroidectomy: a Long Term Comparison of Complications.

    Rosati, Davide / Bononi, Marco / Ruscito, Paolo / Radici, Marco / Cavaliere, Carlo / Minni, Antonio

    Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India

    2021  Band 74, Heft Suppl 3, Seite(n) 6206–6212

    Abstract: The role of prophylactic central compartment neck dissection (CCND) in total thyroidectomy (TT) is controversial in patients without clinically evident lymph nodes metastasis (cN0) because of association with transient and permanent hypoparathyroidism ( ... ...

    Abstract The role of prophylactic central compartment neck dissection (CCND) in total thyroidectomy (TT) is controversial in patients without clinically evident lymph nodes metastasis (cN0) because of association with transient and permanent hypoparathyroidism (HPT) as well as transient and permanent recurrent laryngeal nerve (RLN) injury. Instead of bilateral central neck dissection (bCCND), ipsilateral central compartment neck dissection (iCCND) has recently been proposed as a safer, alternative treatment for selected patients. The aim of this study is to characterize the morbidity that CCND (ipsilateral and bilateral) adds to TT. We enrolled 453 patients: Group A (316 patients) underwent TT alone, Group B (86 patients) underwent TT + iCCND, Group C (51 patients) underwent TT + bCCND. We compared the rates of RLN injury and HPT in three groups and data analysis showed that iCCND was associated with increased rate of transient HPT but not permanent HPT and bCCND was associated with increased rate of transient and permanent HPT, when compared with TT alone. Further studies are needed to evaluate the clear advantages of CCND (both ipsilateral and bilateral), but this should be considered in the context of an higher risk of surgical complications (especially transient and permanent hypoparathyroidism), in comparison with TT alone.
    Sprache Englisch
    Erscheinungsdatum 2021-10-07
    Erscheinungsland India
    Dokumenttyp Journal Article
    ZDB-ID 1471137-0
    ISSN 0973-7707 ; 2231-3796 ; 0019-5421
    ISSN (online) 0973-7707
    ISSN 2231-3796 ; 0019-5421
    DOI 10.1007/s12070-021-02904-2
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  8. Artikel ; Online: Dihadron Fragmentation Functions and Transversity

    Radici Marco / Courtoy A. / Bacchetta Alessandro

    EPJ Web of Conferences, Vol 85, p

    2015  Band 02025

    Abstract: We present preliminary results for an updated extraction of the transversity parton distribution based on the analysis of pion-pair production in deep-inelastic scattering off transversely polarized targets in collinear factorization. Data for proton and ...

    Abstract We present preliminary results for an updated extraction of the transversity parton distribution based on the analysis of pion-pair production in deep-inelastic scattering off transversely polarized targets in collinear factorization. Data for proton and deuteron targets by HERMES and COMPASS allow for a flavor separation of the valence components of transversity, while di-hadron fragmentation functions are taken from the semi-inclusive production of two pion pairs in back-to-back jets in e+e− annihilation. The latter data from Belle have been reanalyzed using the replica method and a more realistic estimate of the uncertainties on the chiral-odd interference fragmentation function has been obtained. After encoding this piece of information into the deep-inelastic scattering cross section, the transversity has been re-extracted by using the most recent and more precise COMPASS data for proton target. This picture represents the current most realistic estimate of the uncertainties on our knowledge of transversity. The preliminary results indicate that the valence up component seems smaller and with a narrower error band than in previous extraction.
    Schlagwörter Physics ; QC1-999 ; Science ; Q
    Sprache Englisch
    Erscheinungsdatum 2015-01-01T00:00:00Z
    Verlag EDP Sciences
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  9. Artikel ; Online: Phenomenology from SIDIS and e+e− multiplicities

    Bacchetta Alessandro / Echevarria Miguel G. / Radici Marco / Signori Andrea

    EPJ Web of Conferences, Vol 85, p

    multiplicities and phenomenology - part I

    2015  Band 02016

    Abstract: This study is part of a project to investigate the transverse momentum dependence in parton distribution and fragmentation functions, analyzing (semi-)inclusive high-energy processes within a proper QCD framework. We calculate the transverse-momentum- ... ...

    Abstract This study is part of a project to investigate the transverse momentum dependence in parton distribution and fragmentation functions, analyzing (semi-)inclusive high-energy processes within a proper QCD framework. We calculate the transverse-momentum-dependent (TMD) multiplicities for e+e− annihilation into two hadrons (considering different combinations of pions and kaons) aiming to investigate the impact of intrinsic and radiative partonic transverse momentum and their mixing with flavor. Different descriptions of the non-perturbative evolution kernel (see, e.g., Refs. [1–5]) are available on the market and there are 200 sets of flavor configurations for the unpolarized TMD fragmentation functions (FFs) resulting from a Monte Carlo fit of Semi-Inclusive Deep-Inelastic Scattering (SIDIS) data at Hermes (see Ref. [6]). We build our predictions of e+e− multiplicities relying on this rich phenomenology. The comparison of these calculations with future experimental data (from Belle and BaBar collaborations) will shed light on non-perturbative aspects of hadron structure, opening important insights into the physics of spin, flavor and momentum structure of hadrons.
    Schlagwörter Physics ; QC1-999 ; Science ; Q
    Thema/Rubrik (Code) 541
    Sprache Englisch
    Erscheinungsdatum 2015-01-01T00:00:00Z
    Verlag EDP Sciences
    Dokumenttyp Artikel ; Online
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  10. Artikel ; Online: TNM classification of the oral cavity carcinomas: some suggested modifications.

    Crescenzi, Domenico / Laus, Melissa / Radici, Marco / Croce, Adelchi

    Otolaryngologia polska = The Polish otolaryngology

    2015  Band 69, Heft 4, Seite(n) 18–27

    Abstract: TNM system is a universally recognized cancer classification. It's based on the assessment of anatomical extent of tumor (T), nodal (N) and distant metastases (M). The first edition of TNM was published in 1968 and has since been updated several times. ... ...

    Abstract TNM system is a universally recognized cancer classification. It's based on the assessment of anatomical extent of tumor (T), nodal (N) and distant metastases (M). The first edition of TNM was published in 1968 and has since been updated several times. Relevant characteristics that affect prognosis prognosis, such as depth of invasion, tumor volume, surgical margin infiltration, and the number of involved nodes as well as the presence of extracapsular spread (such data should be determined by the pathologist and included in pTNM staging – ed. note) are not included in the TNM classification. Following a discussion on most recent classification updates we will discuss the factors, which in our opinion and in concordance with the most recent literature, deserve special consideration and influence management of oral carcinomas.
    Mesh-Begriff(e) Carcinoma, Squamous Cell/classification ; Carcinoma, Squamous Cell/pathology ; Humans ; Lymphatic Metastasis ; Mouth Neoplasms/classification ; Mouth Neoplasms/pathology ; Nasopharyngeal Neoplasms/classification ; Nasopharyngeal Neoplasms/pathology ; Neoplasm Staging ; Oropharyngeal Neoplasms/classification ; Oropharyngeal Neoplasms/pathology ; Pharyngeal Neoplasms/classification ; Pharyngeal Neoplasms/pathology
    Sprache Englisch
    Erscheinungsdatum 2015
    Erscheinungsland Poland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 417458-6
    ISSN 2300-8423 ; 0030-6657
    ISSN (online) 2300-8423
    ISSN 0030-6657
    DOI 10.5604/00306657.1160919
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