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  1. Artikel ; Online: Perspectives on plant flavonoid quercetin-based drugs for novel SARS-CoV-2.

    Saakre, Manjesh / Mathew, Deepu / Ravisankar, V

    Beni-Suef University journal of basic and applied sciences

    2021  Band 10, Heft 1, Seite(n) 21

    Sprache Englisch
    Erscheinungsdatum 2021-03-24
    Erscheinungsland England
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2768279-1
    ISSN 2314-8543 ; 2314-8535 ; 2314-8543
    ISSN (online) 2314-8543
    ISSN 2314-8535 ; 2314-8543
    DOI 10.1186/s43088-021-00107-w
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Bis(benzo-15-crown-5-κ

    Ravisankar, V / Ramesh, V / Krishnamohan, M / Gunasekaran, B / Girisun, T C Sabari

    IUCrData

    2021  Band 6, Heft Pt 1, Seite(n) x210024

    Abstract: The title compound, [Ba( ... ...

    Abstract The title compound, [Ba(C
    Sprache Englisch
    Erscheinungsdatum 2021-01-12
    Erscheinungsland England
    Dokumenttyp Journal Article
    ISSN 2414-3146
    ISSN (online) 2414-3146
    DOI 10.1107/S2414314621000249
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel: Genome-wide microsatellites and species specific markers in genus

    Mathew, Deepu / Anju, P S / Tom, Amala / Johnson, Neethu / Lidia George, M / Davis, Sangeetha P / Ravisankar, V / Asha, K N

    3 Biotech

    2020  Band 10, Heft 10, Seite(n) 442

    Abstract: Genome wide microsatellite maps shall ... ...

    Abstract Genome wide microsatellite maps shall support
    Sprache Englisch
    Erscheinungsdatum 2020-09-18
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 2600522-0
    ISSN 2190-5738 ; 2190-572X
    ISSN (online) 2190-5738
    ISSN 2190-572X
    DOI 10.1007/s13205-020-02430-y
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  4. Artikel ; Online: Optimization of Friction Surfacing Process Parameters for AA1100 Aluminum Alloy Coating with Mild Steel Substrate Using Response Surface Methodology (RSM) Technique

    sugandhi veerasamy / Ravisankar v

    Modern Applied Science, Vol 6, Iss

    2012  Band 2

    Abstract: Friction surfacing was attempted with aluminum on a mild steel substrate. This paper focuses on the development of empirical relationship for the prediction of coating width, coating thickness of friction surfaced materials. Experimental part of the ... ...

    Abstract Friction surfacing was attempted with aluminum on a mild steel substrate. This paper focuses on the development of empirical relationship for the prediction of coating width, coating thickness of friction surfaced materials. Experimental part of the study is based on five level central composite designs of three process parameters. In order to investigate the effects of input parameters on coating width and coating thickness, an empirical relationship is constructed by multiple regression analysis. Optimization of the model is carried out to study the coating width and thickness using design-expert software. Deposit geometry measurements for all the specimens space carried out and compared with the relative impact of input parameters on coating width and thickness in order to verify the measurement errors on the values of the uncertainty in estimated parameters. The results obtained show that the developed empirical relationship can be applied to estimate the effectiveness of process parameters for a given coating width and thickness.
    Schlagwörter Science (General) ; Q1-390 ; Science ; Q
    Thema/Rubrik (Code) 620
    Sprache Englisch
    Erscheinungsdatum 2012-01-01T00:00:00Z
    Verlag Canadian Center of Science and Education
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  5. Artikel: Molecular evolution of the EGF–CFC protein family

    Ravisankar, V / Singh, Taran P / Manoj, Narayanan

    Gene. 2011 Aug. 15, v. 482, no. 1-2

    2011  

    Abstract: The epidermal growth factor-Cripto-1/FRL-1/Cryptic (EGF–CFC) proteins, characterized by the highly conserved EGF and CFC domains, are extracellular membrane associated growth factor-like glycoproteins. These proteins are essential components of the Nodal ...

    Abstract The epidermal growth factor-Cripto-1/FRL-1/Cryptic (EGF–CFC) proteins, characterized by the highly conserved EGF and CFC domains, are extracellular membrane associated growth factor-like glycoproteins. These proteins are essential components of the Nodal signaling pathway during early vertebrate embryogenesis. Homologs of the EGF–CFC family have also been implicated in tumorigenesis in humans. Yet, little is known about the mode of molecular evolution in this family. Here we investigate the origin, extent of conservation and evolutionary relationships of EGF–CFC proteins across the metazoa. The results suggest that the first appearance of the EGF–CFC gene occurred in the ancestor of the deuterostomes. Phylogenetic analysis supports the classification of the family into distinct subfamilies that appear to have evolved through lineage-specific duplication and divergence. Site-specific analyses of evolutionary rate shifts between the two major mammalian paralogous subfamilies, Cripto and Cryptic, reveal critical amino acid sites that may account for the observed functional divergence. Furthermore, estimates of functional divergence suggest that rapid change of evolutionary rates at sites located mainly in the CFC domain may contribute towards distinct functional properties of the two paralogs.
    Schlagwörter amino acids ; carcinogenesis ; embryogenesis ; genes ; glycoproteins ; humans ; phylogeny ; signal transduction
    Sprache Englisch
    Erscheinungsverlauf 2011-0815
    Umfang p. 43-50.
    Erscheinungsort Elsevier B.V.
    Dokumenttyp Artikel
    ZDB-ID 391792-7
    ISSN 1879-0038 ; 0378-1119
    ISSN (online) 1879-0038
    ISSN 0378-1119
    DOI 10.1016/j.gene.2011.05.007
    Datenquelle NAL Katalog (AGRICOLA)

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  6. Artikel ; Online: Molecular evolution of the EGF-CFC protein family.

    Ravisankar, V / Singh, Taran P / Manoj, Narayanan

    Gene

    2011  Band 482, Heft 1-2, Seite(n) 43–50

    Abstract: The epidermal growth factor-Cripto-1/FRL-1/Cryptic (EGF-CFC) proteins, characterized by the highly conserved EGF and CFC domains, are extracellular membrane associated growth factor-like glycoproteins. These proteins are essential components of the Nodal ...

    Abstract The epidermal growth factor-Cripto-1/FRL-1/Cryptic (EGF-CFC) proteins, characterized by the highly conserved EGF and CFC domains, are extracellular membrane associated growth factor-like glycoproteins. These proteins are essential components of the Nodal signaling pathway during early vertebrate embryogenesis. Homologs of the EGF-CFC family have also been implicated in tumorigenesis in humans. Yet, little is known about the mode of molecular evolution in this family. Here we investigate the origin, extent of conservation and evolutionary relationships of EGF-CFC proteins across the metazoa. The results suggest that the first appearance of the EGF-CFC gene occurred in the ancestor of the deuterostomes. Phylogenetic analysis supports the classification of the family into distinct subfamilies that appear to have evolved through lineage-specific duplication and divergence. Site-specific analyses of evolutionary rate shifts between the two major mammalian paralogous subfamilies, Cripto and Cryptic, reveal critical amino acid sites that may account for the observed functional divergence. Furthermore, estimates of functional divergence suggest that rapid change of evolutionary rates at sites located mainly in the CFC domain may contribute towards distinct functional properties of the two paralogs.
    Mesh-Begriff(e) Amino Acid Sequence ; Animals ; Conserved Sequence/genetics ; Epidermal Growth Factor/chemistry ; Evolution, Molecular ; Exons/genetics ; Genetic Variation ; Genome/genetics ; Humans ; Introns/genetics ; Molecular Sequence Data ; Multigene Family ; Phylogeny ; Protein Structure, Tertiary ; Sequence Alignment ; Sequence Homology, Amino Acid
    Chemische Substanzen Epidermal Growth Factor (62229-50-9)
    Sprache Englisch
    Erscheinungsdatum 2011-08-15
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 391792-7
    ISSN 1879-0038 ; 0378-1119
    ISSN (online) 1879-0038
    ISSN 0378-1119
    DOI 10.1016/j.gene.2011.05.007
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  7. Artikel ; Online: Process optimization using response surface methodology for the removal of thorium from aqueous solutions using rice-husk.

    Varala, Sayanasri / Ravisankar, Vivek / Al-Ali, Maha / Pownceby, Mark I / Parthasarathy, Rajarathinam / Bhargava, Suresh K

    Chemosphere

    2019  Band 237, Seite(n) 124488

    Abstract: The adsorptive capability of rice-husk for the sorption of thorium ions from aqueous solutions in batch mode was studied. The key process variables (initial metal ion concentration, initial solution pH and S/L (solid-to-liquid ratio) were optimized for ... ...

    Abstract The adsorptive capability of rice-husk for the sorption of thorium ions from aqueous solutions in batch mode was studied. The key process variables (initial metal ion concentration, initial solution pH and S/L (solid-to-liquid ratio) were optimized for achieving maximum bioremoval efficiency (B%) by employing the Box-Behnken design (33) in response surface methodology (RSM). A quadratic model developed by fitting the experimental data predicted 93% of the responses and estimated the local maximum of B% as >99% for an initial ThIV concentration of 150  g/L, S/L ratio of 5, and an initial pH of 4, and the reported biosorption capacity (qe) is 15.95 mg/g for the same conditions. Freundlich isotherm (R
    Mesh-Begriff(e) Adsorption ; Diffusion ; Hydrogen-Ion Concentration ; Kinetics ; Metals ; Oryza ; Solutions ; Thorium/analysis ; Thorium/chemistry ; Water ; Water Pollutants, Chemical/analysis ; Water Pollutants, Chemical/chemistry
    Chemische Substanzen Metals ; Solutions ; Water Pollutants, Chemical ; Water (059QF0KO0R) ; Thorium (60YU5MIG9W)
    Sprache Englisch
    Erscheinungsdatum 2019-07-30
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2019.124488
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  8. Artikel: Genome-wide microsatellites and species specific markers in genus Phytophthora revealed through whole genome analysis

    Mathew, Deepu / Anju, P. S / Tom, Amala / Johnson, Neethu / Lidia George, M / Davis, Sangeetha P / Ravisankar, V / Asha, K. N

    3 Biotech. 2020 Oct., v. 10, no. 10

    2020  

    Abstract: Genome wide microsatellite maps shall support Phytophthora systematics through the development of reliable markers, enabling species discrimination and variability analyses. Whole genome sequences of 17 Phytophthora accessions belonging to 14 species ... ...

    Abstract Genome wide microsatellite maps shall support Phytophthora systematics through the development of reliable markers, enabling species discrimination and variability analyses. Whole genome sequences of 17 Phytophthora accessions belonging to 14 species were retrieved from GenBank and the genome-wide microsatellites in each species were mined. A total of 51,200 microsatellites, including dinucleotide to decanucleotide motifs, have been identified across all the species and each one was characterized for uniqueness and repeat number. The P. infestans T30-4 genome had the highest (6873) and P. multivora 3378 had the lowest number of microsatellites (1802). Dinucleotide motifs (63.6%) followed by trinucleotide motifs (30.1%) were most abundant in all the genome. From 14 species, 250 microsatellites which are unique for the respective genomes are detailed along with their primer combinations and product sizes. P. sojae had the highest number of unique microsatellite motifs. Genome wide microsatellite maps for all the 14 Phytophthora species including the chromosome, position, motif, repeat number, forward and reverse primer sequences and expected PCR product size, for every microsatellite are presented. Markers based on the unique microsatellites could be used to identify each species, whereas the ones common to all species could be used to identify the genetic variability. Furthermore, to confirm the results, pure cultures of P. capsici, P. nicotianae and P. palmivora were procured from the Phytophthora Repository, DNA was isolated and the unique markers were screened across the species. The characteristic markers developed have confirmed the genome analysis results.
    Schlagwörter DNA ; chromosomes ; genetic variation ; genome ; microsatellite repeats ; sequence analysis
    Sprache Englisch
    Erscheinungsverlauf 2020-10
    Umfang p. 442.
    Erscheinungsort Springer International Publishing
    Dokumenttyp Artikel
    Anmerkung NAL-AP-2-clean
    ZDB-ID 2600522-0
    ISSN 2190-5738 ; 2190-572X
    ISSN (online) 2190-5738
    ISSN 2190-572X
    DOI 10.1007/s13205-020-02430-y
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  9. Artikel: Acute angle closure glaucoma after hypospadias surgery: A vision-threatening complication of oxybutynin.

    Jain, Divya / Dhua, Anjan / Ravisankar, Venkateshwar / Chellam, Lavanya / Joshi, Manoj

    Journal of Indian Association of Pediatric Surgeons

    2014  Band 20, Heft 3, Seite(n) 161–162

    Sprache Englisch
    Erscheinungsdatum 2014-05-29
    Erscheinungsland India
    Dokumenttyp Journal Article
    ZDB-ID 2164528-0
    ISSN 1998-3891 ; 0971-9261
    ISSN (online) 1998-3891
    ISSN 0971-9261
    DOI 10.4103/0971-9261.154662
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  10. Artikel ; Online: Design, characterization and antimalarial efficacy of PEGylated galactosylated nano lipid carriers of primaquine phosphate.

    Baruah, Uday Krishna / Gowthamarajan, Kuppusamy / Ravisankar, Vanka / Karri, Veera Venkata Satyanarayana Reddy / Simhadri, Praveen Kumar / Singh, Vineeta / Babu, Phanithi Prakash

    Artificial cells, nanomedicine, and biotechnology

    2017  Band 46, Heft 8, Seite(n) 1809–1829

    Abstract: This study was aimed to design and optimize primaquine phosphate (PQ) loaded nanostructured lipid carriers (NLCs) using response surface methodology. The optimized NLCs were evaluated for various physical and morphological characterizations. The in vitro ...

    Abstract This study was aimed to design and optimize primaquine phosphate (PQ) loaded nanostructured lipid carriers (NLCs) using response surface methodology. The optimized NLCs were evaluated for various physical and morphological characterizations. The in vitro studies for drug release showed that PQ loaded NLCs had a sustained release up to 72 h and the stability studies confirmed that the PQ-NLCs were stable for 90 d at 4 °C and 25 °C. In vitro erythrocyte toxicity revealed that PQ-NLCs were less toxic than the pure drug. In vitro parasite growth inhibition assay showed an IC
    Mesh-Begriff(e) Animals ; Antimalarials/chemistry ; Antimalarials/pharmacokinetics ; Antimalarials/pharmacology ; Drug Carriers/chemistry ; Drug Carriers/pharmacokinetics ; Drug Carriers/pharmacology ; Humans ; Lipids/chemistry ; Lipids/pharmacokinetics ; Lipids/pharmacology ; Malaria, Falciparum/drug therapy ; Malaria, Falciparum/metabolism ; Malaria, Falciparum/pathology ; Mice ; Nanoparticles/chemistry ; Plasmodium falciparum/growth & development ; Polyethylene Glycols/chemistry ; Polyethylene Glycols/pharmacokinetics ; Polyethylene Glycols/pharmacology ; Primaquine/chemistry ; Primaquine/pharmacokinetics ; Primaquine/pharmacology
    Chemische Substanzen Antimalarials ; Drug Carriers ; Lipids ; Polyethylene Glycols (3WJQ0SDW1A) ; Primaquine (MVR3634GX1)
    Sprache Englisch
    Erscheinungsdatum 2017-10-31
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2723095-8
    ISSN 2169-141X ; 2169-1401
    ISSN (online) 2169-141X
    ISSN 2169-1401
    DOI 10.1080/21691401.2017.1394870
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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