Artikel ; Online: Titanium-Catalyzed Exhaustive Reduction of Oxo-Chemicals.
Angewandte Chemie (International ed. in English)
2022 Band 61, Heft 46, Seite(n) e202209232
Abstract: Catalytic reduction of carboxylic acids and derivatives all the way to their corresponding methyl-compounds is very rare and still challenging for homogeneous transition-metal catalysis. Herein, we report an unprecedented and general catalytic exhaustive ...
Abstract | Catalytic reduction of carboxylic acids and derivatives all the way to their corresponding methyl-compounds is very rare and still challenging for homogeneous transition-metal catalysis. Herein, we report an unprecedented and general catalytic exhaustive reduction of carboxylic functional group straightforwardly to a methyl group. This reaction was achieved using earth-abundant and readily available titanium as a catalyst. Our system has broad functional group tolerance and works for various other types of oxo-chemicals such as alcohols, aldehydes, ketones, lactones, and carboxylates (>100 examples). Preliminary mechanistic studies revealed that the in situ-generated Ti |
---|---|
Sprache | Englisch |
Erscheinungsdatum | 2022-10-17 |
Erscheinungsland | Germany |
Dokumenttyp | Journal Article |
ZDB-ID | 2011836-3 |
ISSN | 1521-3773 ; 1433-7851 |
ISSN (online) | 1521-3773 |
ISSN | 1433-7851 |
DOI | 10.1002/anie.202209232 |
Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
Volltext online
Zusatzmaterialien
Kategorien
Über subito bestellen
Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.