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  1. Artikel: A generalized deep learning network for fractional anisotropy reconstruction: Application to epilepsy and multiple sclerosis.

    Gaviraghi, Marta / Ricciardi, Antonio / Palesi, Fulvia / Brownlee, Wallace / Vitali, Paolo / Prados, Ferran / Kanber, Baris / Gandini Wheeler-Kingshott, Claudia A M

    Frontiers in neuroinformatics

    2022  Band 16, Seite(n) 891234

    Abstract: Fractional anisotropy (FA) is a quantitative map sensitive to microstructural properties of ... ...

    Abstract Fractional anisotropy (FA) is a quantitative map sensitive to microstructural properties of tissues
    Sprache Englisch
    Erscheinungsdatum 2022-08-05
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2452979-5
    ISSN 1662-5196
    ISSN 1662-5196
    DOI 10.3389/fninf.2022.891234
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  2. Artikel ; Online: What contributes to disability in progressive MS? A brain and cervical cord-matched quantitative MRI study.

    Tur, Carmen / Battiston, Marco / Yiannakas, Marios C / Collorone, Sara / Calvi, Alberto / Prados, Ferran / Kanber, Baris / Grussu, Francesco / Ricciardi, Antonio / Pajak, Patrizia / Martinelli, Daniele / Schneider, Torben / Ciccarelli, Olga / Samson, Rebecca S / Wheeler-Kingshott, Claudia Am Gandini

    Multiple sclerosis (Houndmills, Basingstoke, England)

    2024  Band 30, Heft 4-5, Seite(n) 516–534

    Abstract: Background: We assessed the ability of a brain-and-cord-matched quantitative magnetic resonance imaging (qMRI) protocol to differentiate patients with progressive multiple sclerosis (PMS) from controls, in terms of normal-appearing (NA) tissue ... ...

    Abstract Background: We assessed the ability of a brain-and-cord-matched quantitative magnetic resonance imaging (qMRI) protocol to differentiate patients with progressive multiple sclerosis (PMS) from controls, in terms of normal-appearing (NA) tissue abnormalities, and explain disability.
    Methods: A total of 27 patients and 16 controls were assessed on the Expanded Disability Status Scale (EDSS), 25-foot timed walk (TWT), 9-hole peg (9HPT) and symbol digit modalities (SDMT) tests. All underwent 3T brain and (C2-C3) cord structural imaging and qMRI (relaxometry, quantitative magnetisation transfer, multi-shell diffusion-weighted imaging), using a fast brain-and-cord-matched protocol with brain-and-cord-unified imaging readouts. Lesion and NA-tissue volumes and qMRI metrics reflecting demyelination and axonal loss were obtained. Random forest analyses identified the most relevant volumetric/qMRI measures to clinical outcomes. Confounder-adjusted linear regression estimated the actual MRI-clinical associations.
    Results: Several qMRI/volumetric differences between patients and controls were observed (
    Conclusion: Fast brain-and-cord-matched qMRI protocols are feasible and identify demyelination - combined with other mechanisms - as key for disability accumulation in PMS.
    Mesh-Begriff(e) Humans ; Cervical Cord/pathology ; Multiple Sclerosis/pathology ; Brain/pathology ; Magnetic Resonance Imaging/methods ; Multiple Sclerosis, Chronic Progressive/pathology ; Gray Matter/pathology
    Sprache Englisch
    Erscheinungsdatum 2024-02-19
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 1290669-4
    ISSN 1477-0970 ; 1352-4585
    ISSN (online) 1477-0970
    ISSN 1352-4585
    DOI 10.1177/13524585241229969
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4428: Hefte anzeigen Standort:
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  3. Artikel: Patterns of inflammation, microstructural alterations, and sodium accumulation define multiple sclerosis subtypes after 15 years from onset.

    Ricciardi, Antonio / Grussu, Francesco / Kanber, Baris / Prados, Ferran / Yiannakas, Marios C / Solanky, Bhavana S / Riemer, Frank / Golay, Xavier / Brownlee, Wallace / Ciccarelli, Olga / Alexander, Daniel C / Gandini Wheeler-Kingshott, Claudia A M

    Frontiers in neuroinformatics

    2023  Band 17, Seite(n) 1060511

    Abstract: Introduction: Conventional MRI is routinely used for the characterization of pathological changes in multiple sclerosis (MS), but due to its lack of specificity is unable to provide accurate prognoses, explain disease heterogeneity and reconcile the gap ...

    Abstract Introduction: Conventional MRI is routinely used for the characterization of pathological changes in multiple sclerosis (MS), but due to its lack of specificity is unable to provide accurate prognoses, explain disease heterogeneity and reconcile the gap between observed clinical symptoms and radiological evidence. Quantitative MRI provides measures of physiological abnormalities, otherwise invisible to conventional MRI, that correlate with MS severity. Analyzing quantitative MRI measures through machine learning techniques has been shown to improve the understanding of the underlying disease by better delineating its alteration patterns.
    Methods: In this retrospective study, a cohort of healthy controls (HC) and MS patients with different subtypes, followed up 15 years from clinically isolated syndrome (CIS), was analyzed to produce a multi-modal set of quantitative MRI features encompassing relaxometry, microstructure, sodium ion concentration, and tissue volumetry. Random forest classifiers were used to train a model able to discriminate between HC, CIS, relapsing remitting (RR) and secondary progressive (SP) MS patients based on these features and, for each classification task, to identify the relative contribution of each MRI-derived tissue property to the classification task itself.
    Results and discussion: Average classification accuracy scores of 99 and 95% were obtained when discriminating HC and CIS vs. SP, respectively; 82 and 83% for HC and CIS vs. RR; 76% for RR vs. SP, and 79% for HC vs. CIS. Different patterns of alterations were observed for each classification task, offering key insights in the understanding of MS phenotypes pathophysiology: atrophy and relaxometry emerged particularly in the classification of HC and CIS vs. MS, relaxometry within lesions in RR vs. SP, sodium ion concentration in HC vs. CIS, and microstructural alterations were involved across all tasks.
    Sprache Englisch
    Erscheinungsdatum 2023-03-23
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2452979-5
    ISSN 1662-5196
    ISSN 1662-5196
    DOI 10.3389/fninf.2023.1060511
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  4. Buch: Il distretto della pesca di Mazara del Vallo

    Fazio, Vincenzo / Ricciardi, Antonio

    una buona pratica di cooperazione tra aziende internazionali

    (Economia : Ricerche ; 688)

    2008  

    Verfasserangabe a cura di Vincenzo Fazio, Antonio Ricciardi
    Serientitel Economia : Ricerche ; 688
    Schlagwörter Fischwirtschaft ; Regionales Cluster ; Internationale Unternehmenskooperation ; Fischereipolitik ; Mittelmeerraum ; Italien ; Sizilien
    Sprache Italienisch
    Umfang 169 p., ill., 23 cm
    Verlag F. Angeli
    Erscheinungsort Milano
    Dokumenttyp Buch
    Anmerkung Enth. 5 Beitr. ; Half title: Unione europea; Regione siciliana, Assessorato ; Includes bibliographical references ; Mazara del Vallo, near Trapani (Sicily)
    ISBN 9788856813593 ; 8856813599
    Datenquelle ECONomics Information System

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  5. Buch: Relazioni di cooperazione e reti di imprese

    Izzo, Francesco / Ricciardi, Antonio

    il caso della Campania

    (Economia : Sez. 5 ; 448)

    2006  

    Verfasserangabe a cura di Francesco Izzo; Antonio Ricciardi; introduzione di Vincenzo Maggioni
    Serientitel Economia : Sez. 5 ; 448
    Schlagwörter Industriestruktur ; Unternehmenskooperation ; Unternehmensnetzwerk ; Regionales Cluster ; Kampanien ; 60#39
    Sprache Italienisch
    Umfang XIV, 374 S., graph. Darst., 23 cm
    Verlag F. Angeli
    Erscheinungsort Milano
    Dokumenttyp Buch
    Anmerkung Contains bibliography, bibliographical references and notes ; Enth. 6 Beitr. ; On cover: IPE, Istituto per ricerche e attività educative ; On t.p.: SUN, Seconda Università degli studi di Napoli
    ISBN 8846476360 ; 9788846476364
    Datenquelle ECONomics Information System

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  6. Artikel ; Online: Integrating hazard, exposure, vulnerability and resilience for risk and emergency management in a volcanic context: the ADVISE model.

    Bonadonna, Costanza / Frischknecht, Corine / Menoni, Scira / Romerio, Franco / Gregg, Chris E / Rosi, Mauro / Biass, Sebastien / Asgary, Ali / Pistolesi, Marco / Guobadia, Dehrick / Gattuso, Alessandro / Ricciardi, Antonio / Cristiani, Chiara

    Journal of applied volcanology

    2021  Band 10, Heft 1, Seite(n) 7

    Abstract: Risk assessments in volcanic contexts are complicated by the multi-hazard nature of both unrest and eruption phases, which frequently occur over a wide range of spatial and temporal scales. As an attempt to capture the multi-dimensional and dynamic ... ...

    Abstract Risk assessments in volcanic contexts are complicated by the multi-hazard nature of both unrest and eruption phases, which frequently occur over a wide range of spatial and temporal scales. As an attempt to capture the multi-dimensional and dynamic nature of volcanic risk, we developed an
    Supplementary information: The online version contains supplementary material available at 10.1186/s13617-021-00108-5.
    Sprache Englisch
    Erscheinungsdatum 2021-11-08
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ISSN 2191-5040
    ISSN (online) 2191-5040
    DOI 10.1186/s13617-021-00108-5
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  7. Artikel: Comparison of Neurite Orientation Dispersion and Density Imaging and Two-Compartment Spherical Mean Technique Parameter Maps in Multiple Sclerosis.

    Johnson, Daniel / Ricciardi, Antonio / Brownlee, Wallace / Kanber, Baris / Prados, Ferran / Collorone, Sara / Kaden, Enrico / Toosy, Ahmed / Alexander, Daniel C / Gandini Wheeler-Kingshott, Claudia A M / Ciccarelli, Olga / Grussu, Francesco

    Frontiers in neurology

    2021  Band 12, Seite(n) 662855

    Abstract: Background: ...

    Abstract Background:
    Sprache Englisch
    Erscheinungsdatum 2021-06-14
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2564214-5
    ISSN 1664-2295
    ISSN 1664-2295
    DOI 10.3389/fneur.2021.662855
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Cardiovascular risk factors in secondary progressive multiple sclerosis: A cross-sectional analysis from the MS-STAT2 randomized controlled trial.

    Williams, Thomas / John, Nevin / Calvi, Alberto / Bianchi, Alessia / De Angelis, Floriana / Doshi, Anisha / Wright, Sarah / Shatila, Madiha / Yiannakas, Marios C / Chowdhury, Fatima / Stutters, Jon / Ricciardi, Antonio / Prados, Ferran / MacManus, David / Braisher, Marie / Blackstone, James / Ciccarelli, Olga / Gandini Wheeler-Kingshott, Claudia A M / Barkhof, Frederik /
    Chataway, Jeremy

    European journal of neurology

    2023  Band 30, Heft 9, Seite(n) 2769–2780

    Abstract: Background and purpose: There is increasing evidence that cardiovascular risk (CVR) contributes to disability progression in multiple sclerosis (MS). CVR is particularly prevalent in secondary progressive MS (SPMS) and can be quantified through ... ...

    Abstract Background and purpose: There is increasing evidence that cardiovascular risk (CVR) contributes to disability progression in multiple sclerosis (MS). CVR is particularly prevalent in secondary progressive MS (SPMS) and can be quantified through validated composite CVR scores. The aim was to examine the cross-sectional relationships between excess modifiable CVR, whole and regional brain atrophy on magnetic resonance imaging, and disability in patients with SPMS.
    Methods: Participants had SPMS, and data were collected at enrolment into the MS-STAT2 trial. Composite CVR scores were calculated using the QRISK3 software. Prematurely achieved CVR due to modifiable risk factors was expressed as QRISK3 premature CVR, derived through reference to the normative QRISK3 dataset and expressed in years. Associations were determined with multiple linear regressions.
    Results: For the 218 participants, mean age was 54 years and median Expanded Disability Status Scale was 6.0. Each additional year of prematurely achieved CVR was associated with a 2.7 mL (beta coefficient; 95% confidence interval 0.8-4.7; p = 0.006) smaller normalized whole brain volume. The strongest relationship was seen for the cortical grey matter (beta coefficient 1.6 mL per year; 95% confidence interval 0.5-2.7; p = 0.003), and associations were also found with poorer verbal working memory performance. Body mass index demonstrated the strongest relationships with normalized brain volumes, whilst serum lipid ratios demonstrated strong relationships with verbal and visuospatial working memory performance.
    Conclusions: Prematurely achieved CVR is associated with lower normalized brain volumes in SPMS. Future longitudinal analyses of this clinical trial dataset will be important to determine whether CVR predicts future disease worsening.
    Mesh-Begriff(e) Humans ; Middle Aged ; Multiple Sclerosis/pathology ; Multiple Sclerosis, Chronic Progressive/diagnostic imaging ; Multiple Sclerosis, Chronic Progressive/pathology ; Cardiovascular Diseases/diagnostic imaging ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/etiology ; Cross-Sectional Studies ; Risk Factors ; Brain/diagnostic imaging ; Brain/pathology ; Magnetic Resonance Imaging/methods ; Memory, Short-Term ; Heart Disease Risk Factors ; Atrophy/pathology ; Disability Evaluation ; Disease Progression ; STAT2 Transcription Factor
    Chemische Substanzen STAT2 protein, human ; STAT2 Transcription Factor
    Sprache Englisch
    Erscheinungsdatum 2023-06-23
    Erscheinungsland England
    Dokumenttyp Randomized Controlled Trial ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1280785-0
    ISSN 1468-1331 ; 1351-5101 ; 1471-0552
    ISSN (online) 1468-1331
    ISSN 1351-5101 ; 1471-0552
    DOI 10.1111/ene.15924
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Verfügbar in ZB MED Köln/Königswinter

    Zs.A 4738: Hefte anzeigen Standort:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 592: Hefte anzeigen

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  9. Buch ; Online: Assessing the effectiveness and the economic impact of evacuation

    Bonadonna, Costanza / Asgary, Ali / Romerio, Franco / Zulemyan, Tais / Frischknecht, Corine / Cristiani, Chiara / Rosi, Mauro / Gregg, Chris E. / Biass, Sebastien / Pistolesi, Marco / Menoni, Scira / Ricciardi, Antonio

    eISSN: 1684-9981

    the case of Vulcano Island, Italy

    2021  

    Abstract: Evacuation planning and management represents a key aspect of volcanic crises because it can increase people protection as well as minimize the potential impact on the economy, properties, and infrastructure of the affected area. Assessment of evacuation ...

    Abstract Evacuation planning and management represents a key aspect of volcanic crises because it can increase people protection as well as minimize the potential impact on the economy, properties, and infrastructure of the affected area. Assessment of evacuation scenarios that consider human and economic impact is best done in a pre-disaster context as it helps authorities develop evacuation plans and make informed decisions outside the highly stressful time period that characterizes crises. We present an agent-based simulation tool that assesses the effectiveness of different evacuation scenarios using Vulcano island (Italy) as a case study. Simulation results show that the overall time needed to evacuate people should be analysed together with the percentage of people evacuated as a function of time and that a simultaneous evacuation on Vulcano is more efficient than a staged evacuation. We also present a model to assess the economic impact of evacuation as a function of evacuation duration and starting period that reveals that an evacuation of Vulcano would cause significant economic impact to the tourism industry if lasting more than 3 months (in case it was initiated at the beginning of the visitor season) to 1 year (in case it was initiated at the end of the visitor season).
    Thema/Rubrik (Code) 910
    Sprache Englisch
    Erscheinungsdatum 2021-10-15
    Erscheinungsland de
    Dokumenttyp Buch ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  10. Artikel: Concorrenza e integrazione fra banche e intermediari non bancari nella gestione dei servizi di pagamento

    Ricciardi, Antonio

    Rassegna economica : rivista internazionale di economia e territorio 59. 1995 ,4, S. 797-812

    1996  

    Verfasserangabe Antonio Ricciardi
    Schlagwörter Zahlungsverkehr ; Theorie ; Italien ; Bank
    Sprache Italienisch
    Erscheinungsort Napoli
    Dokumenttyp Artikel
    Anmerkung Sprache der Zusammenfassung: Englisch ; Competition and integration between banks and non-bank financial intermediaries in the management of payment systems
    ZDB-ID 861012-5 ; 2418418-4
    ISSN 0390-010X
    ISSN 0390-010X
    Datenquelle ECONomics Information System

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