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  1. Book ; Online ; Thesis: Wiederverwertung von behandeltem Abwasser in der Landwirtschaft

    Riemenschneider, Christina

    Untersuchungen zum Verbleib von organischen Spurenstoffen in Nutzpflanzen mittels LC-MS

    (Dissertation / Helmholtz Zentrum für Umweltforschung - UFZ ; 10/2017)

    2017  

    Institution Universität Leipzig
    Author's details Christina Riemenschneider
    Series title Dissertation / Helmholtz Zentrum für Umweltforschung - UFZ ; 10/2017
    UFZ-Dissertation
    Collection UFZ-Dissertation
    Subject code 630
    Language English
    Size 1 Online-Ressource (177 Seiten), Illustrationen
    Publisher Helmholtz Zentrum für Umweltforschung - UFZ
    Publishing place Leipzig
    Publishing country Germany
    Document type Book ; Online ; Thesis
    Thesis / German Habilitation thesis Dissertation, Universität Leipzig, 2017
    Remark Elektronischer Volltext
    HBZ-ID HT019655384
    DOI 10.4126/FRL01-006407780
    Database Repository for Life Sciences

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  2. Book ; Thesis: Wiederverwendung von behandeltem Abwasser in der Landwirtschaft

    Riemenschneider, Christina

    Untersuchungen zum Verbleib von organischen Spurenstoffen in Nutzpflanzen mittels LC-MS

    (Dissertation ; 2017,10)

    2017  

    Institution Universität Leipzig / Fakultät für Chemie und Mineralogie
    Author's details vorgelegt von Christina Riemenschneider
    Series title Dissertation ; 2017,10
    Dissertation / Helmholtz-Zentrum für Umweltforschung, UFZ
    Collection Dissertation / Helmholtz-Zentrum für Umweltforschung, UFZ
    Language German
    Size XI, 160, V, 10 Seiten, Illustrationen, Diagramme
    Publisher Helmholtz Zentrum für Umweltforschung - UFZ
    Publishing place Leipzig
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Universität Leipzig, Fakultät für Chemie und Mineralogie, 2017
    HBZ-ID HT019484342
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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  3. Book ; Online ; Thesis: Wiederverwertung von behandeltem Abwasser in der Landwirtschaft

    Riemenschneider, Christina

    Untersuchungen zum Verbleib von organischen Spurenstoffen in Nutzpflanzen mittels LC-MS

    (Dissertation / Helmholtz Zentrum für Umweltforschung - UFZ ; 10/2017)

    2017  

    Institution Universität Leipzig
    Author's details Christina Riemenschneider
    Series title Dissertation / Helmholtz Zentrum für Umweltforschung - UFZ ; 10/2017
    UFZ-Dissertation
    Collection UFZ-Dissertation
    Subject code 630
    Language English
    Size 1 Online-Ressource (177 Seiten), Illustrationen
    Publisher Helmholtz Zentrum für Umweltforschung - UFZ
    Publishing place Leipzig
    Publishing country Germany
    Document type Book ; Online ; Thesis
    Thesis / German Habilitation thesis Dissertation, Universität Leipzig, 2017
    Remark Elektronischer Volltext
    HBZ-ID HT019655384
    DOI 10.4126/FRL01-006407780
    Database Repository for Life Sciences

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  4. Book: Wiederverwendung von behandeltem Abwasser in der Landwirtschaft

    Riemenschneider, Christina

    Untersuchungen zum Verbleib von organischen Spurenstoffen in Nutzpflanzen mittels LC-MS

    (Dissertation / Helmholtz-Zentrum für Umweltforschung - UFZ ; 2017,10)

    2017  

    Institution UFZ-Umweltforschungszentrum Leipzig-Halle
    Universität Leipzig
    Author's details vorgelegt von Christina Riemenschneider, M. Sc
    Series title Dissertation / Helmholtz-Zentrum für Umweltforschung - UFZ ; 2017,10
    Keywords Spurenstoff ; Nutzpflanzen ; Abwasser
    Language German ; English
    Size circa 190 Seiten, Illustrationen, Diagramme
    Publisher Helmholtz-Zentrum für Umweltforschung - UFZ
    Publishing place Leipzig
    Document type Book
    Note Text teilweise in deutscher, teilweise in englischer Sprache ; Enthält außerdem 2 Originalpublikationen und 1 Manuskript
    Database Julius Kühn-Institute

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  5. Article: Rückstände von Chlorat und quartären Ammoniumverbindungen in Pangasiusfilet

    Dambacher, Benjamin / Riemenschneider, Christina / Hardebusch, Björn

    MTA- Dialog

    2020  Volume 21, Issue 5, Page(s) 18–21

    Abstract: Fischprodukte sind sehr empfindliche Lebensmittel. Um die Qualität und Frische der Fischprodukte im tiefgefrorenen Zustand zu erhalten, wird ihre Oberfläche häufig mit einer Schutzschicht aus Wasser überzogen, indem das tiefgefrorene Erzeugnis kurzzeitig ...

    Abstract Fischprodukte sind sehr empfindliche Lebensmittel. Um die Qualität und Frische der Fischprodukte im tiefgefrorenen Zustand zu erhalten, wird ihre Oberfläche häufig mit einer Schutzschicht aus Wasser überzogen, indem das tiefgefrorene Erzeugnis kurzzeitig in Trinkwasser eingetaucht oder mit Trinkwasser...
    Keywords Fischprodukte ; Kontaminationsquellen ; Untersuchungsergebnisse
    Language German
    Document type Article
    ZDB-ID 2021212-4
    ISSN 1439-071X
    ISSN 1439-071X
    Database bibnet.org

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  6. Book ; Online ; Thesis: Reacquisition and maintenance of pluripotency

    Riemenschneider, Christina [Verfasser] / Meissner, Alexander [Akademischer Betreuer] / Bartfel, Sina [Gutachter] / Meissner, Alexander [Gutachter]

    2023  

    Author's details Christina Riemenschneider ; Gutachter: Sina Bartfel, Alexander Meissner ; Betreuer: Alexander Meissner
    Keywords Biowissenschaften, Biologie ; Life Science, Biology
    Subject code sg570
    Language English
    Publisher Technische Universität Berlin
    Publishing place Berlin
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  7. Article ; Online: Reconstructing axial progenitor field dynamics in mouse stem cell-derived embryoids.

    Bolondi, Adriano / Law, Benjamin K / Kretzmer, Helene / Gassaloglu, Seher Ipek / Buschow, René / Riemenschneider, Christina / Yang, Dian / Walther, Maria / Veenvliet, Jesse V / Meissner, Alexander / Smith, Zachary D / Chan, Michelle M

    Developmental cell

    2024  

    Abstract: Embryogenesis requires substantial coordination to translate genetic programs to the collective behavior of differentiating cells, but understanding how cellular decisions control tissue morphology remains conceptually and technically challenging. Here, ... ...

    Abstract Embryogenesis requires substantial coordination to translate genetic programs to the collective behavior of differentiating cells, but understanding how cellular decisions control tissue morphology remains conceptually and technically challenging. Here, we combine continuous Cas9-based molecular recording with a mouse embryonic stem cell-based model of the embryonic trunk to build single-cell phylogenies that describe the behavior of transient, multipotent neuro-mesodermal progenitors (NMPs) as they commit into neural and somitic cell types. We find that NMPs show subtle transcriptional signatures related to their recent differentiation and contribute to downstream lineages through a surprisingly broad distribution of individual fate outcomes. Although decision-making can be heavily influenced by environmental cues to induce morphological phenotypes, axial progenitors intrinsically mature over developmental time to favor the neural lineage. Using these data, we present an experimental and analytical framework for exploring the non-homeostatic dynamics of transient progenitor populations as they shape complex tissues during critical developmental windows.
    Language English
    Publishing date 2024-04-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2054967-2
    ISSN 1878-1551 ; 1534-5807
    ISSN (online) 1878-1551
    ISSN 1534-5807
    DOI 10.1016/j.devcel.2024.03.024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Extensive Transformation of the Pharmaceutical Carbamazepine Following Uptake into Intact Tomato Plants.

    Riemenschneider, Christina / Seiwert, Bettina / Moeder, Monika / Schwarz, Dietmar / Reemtsma, Thorsten

    Environmental science & technology

    2017  Volume 51, Issue 11, Page(s) 6100–6109

    Abstract: Carbamazepine (CBZ) is an antiepileptic drug which is persistent in wastewater treatment plants and the environment. It has been frequently detected in plant material after irrigation with treated wastewater. To date, little information is, however, ... ...

    Abstract Carbamazepine (CBZ) is an antiepileptic drug which is persistent in wastewater treatment plants and the environment. It has been frequently detected in plant material after irrigation with treated wastewater. To date, little information is, however, available on the transformation of CBZ in plants. In the present study, the uptake, translocation, and transformation of CBZ was studied in hydroponically grown tomato plants. After 35 days of exposure >80% of the total spiked amount of CBZ was taken by the tomato plants and mainly stored in the leaves. A total of 11 transformation products (TP) (mainly phase-I) were quantified by liquid chromatography-tandem mass spectrometry (LC-MS/MS) and their total amount corresponded to 33% of the CBZ taken up. The ratio of CBZ metabolites to CBZ was highest in fruits (up to 2.5) and leaves (0.5), suggesting an intensive transformation of CBZ in these compartments. Further 10 TPs (phase-I and II) were identified by LC-high resolution mass spectrometry screening, likely comprising another 12% of CBZ. On the basis of these experiments and on an experiment with CBZ-10,11-epoxide a transformation pathway of CBZ in intact tomato plants is proposed that involves epoxidation, hydrolysis, hydroxylation, ring contraction, or loss of the carbamoyl group, followed by conjugation to glucose or cysteine, but also reduction of CBZ. This transformation pathway and analytical data of CBZ transformation products allow for their determination also in field grown vegetable and for the generation of more accurate exposure data of consumers of vegetable irrigated with treated municipal wastewater.
    Language English
    Publishing date 2017-06-06
    Publishing country United States
    Document type Journal Article
    ISSN 1520-5851
    ISSN (online) 1520-5851
    DOI 10.1021/acs.est.6b06485
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Photochemically Induced Bound Residue Formation of Carbamazepine with Dissolved Organic Matter

    Raeke, Julia / Lechtenfeld Oliver J / Meier Till / Reemtsma Thorsten / Riemenschneider Christina / Seiwert Bettina

    Environmental Science & Technology. 2017 May 16, v. 51, no. 10

    2017  

    Abstract: More than 400 new nitrogen containing products were detected upon experimental sunlight photolysis of the pharmaceutical carbamazepine (CBZ) in the presence of dissolved organic matter (DOM) by Fourier transform ion cyclotron resonance mass spectrometry ( ...

    Abstract More than 400 new nitrogen containing products were detected upon experimental sunlight photolysis of the pharmaceutical carbamazepine (CBZ) in the presence of dissolved organic matter (DOM) by Fourier transform ion cyclotron resonance mass spectrometry (FTICR-MS). These products were presumably formed through covalent binding of CBZ phototransformation products with DOM molecules. About 50% of these newly formed bound residues contained one nitrogen atom and had a molecular mass between 375 and 525 Da, which was 150 to 200 Da higher than for an average DOM molecule. In addition, a previously unknown CBZ phototransformation product, 3-quinolinecarboxylic acid (3-QCA), was identified by liquid chromatography high resolution tandem mass spectrometry (LC-HRMS/MS). 3-QCA was likely formed through oxidative ring cleavage and subsequent decarboxylation of acridine, a well-known phototransformation product of CBZ. Collision induced dissociation experiments and Kendrick mass defect analyses corroborated that about 160 of the new products were formed via covalent binding of 3-QCA with DOM molecules of above-average O/C and H/C ratios. Experiments at lower CBZ concentration suggested that the importance of bound residue formation increases with increasing DOM/CBZ ratios. Photochemically induced bound residue formation of polar contaminants with DOM in the aqueous phase is thus a disregarded pathway along which contaminants can be transformed in the environment. The method presented here offers a new possibility to study the formation of bound residues, which may be of relevance also for other transformation processes in natural waters where radical intermediates are generated.
    Keywords decarboxylation ; dissociation ; dissolved organic matter ; liquid chromatography ; molecular weight ; new products ; nitrogen ; photolysis ; solar radiation ; tandem mass spectrometry
    Language English
    Dates of publication 2017-0516
    Size p. 5523-5530.
    Publishing place American Chemical Society
    Document type Article
    ISSN 1520-5851
    DOI 10.1021%2Facs.est.7b00823
    Database NAL-Catalogue (AGRICOLA)

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  10. Article: Extensive Transformation of the Pharmaceutical Carbamazepine Following Uptake into Intact Tomato Plants

    Riemenschneider, Christina / Moeder Monika / Reemtsma Thorsten / Schwarz Dietmar / Seiwert Bettina

    Environmental Science & Technology. 2017 June 06, v. 51, no. 11

    2017  

    Abstract: Carbamazepine (CBZ) is an antiepileptic drug which is persistent in wastewater treatment plants and the environment. It has been frequently detected in plant material after irrigation with treated wastewater. To date, little information is, however, ... ...

    Abstract Carbamazepine (CBZ) is an antiepileptic drug which is persistent in wastewater treatment plants and the environment. It has been frequently detected in plant material after irrigation with treated wastewater. To date, little information is, however, available on the transformation of CBZ in plants. In the present study, the uptake, translocation, and transformation of CBZ was studied in hydroponically grown tomato plants. After 35 days of exposure >80% of the total spiked amount of CBZ was taken by the tomato plants and mainly stored in the leaves. A total of 11 transformation products (TP) (mainly phase-I) were quantified by liquid chromatography–tandem mass spectrometry (LC-MS/MS) and their total amount corresponded to 33% of the CBZ taken up. The ratio of CBZ metabolites to CBZ was highest in fruits (up to 2.5) and leaves (0.5), suggesting an intensive transformation of CBZ in these compartments. Further 10 TPs (phase-I and II) were identified by LC-high resolution mass spectrometry screening, likely comprising another 12% of CBZ. On the basis of these experiments and on an experiment with CBZ-10,11-epoxide a transformation pathway of CBZ in intact tomato plants is proposed that involves epoxidation, hydrolysis, hydroxylation, ring contraction, or loss of the carbamoyl group, followed by conjugation to glucose or cysteine, but also reduction of CBZ. This transformation pathway and analytical data of CBZ transformation products allow for their determination also in field grown vegetable and for the generation of more accurate exposure data of consumers of vegetable irrigated with treated municipal wastewater.
    Keywords cysteine ; fruits ; glucose ; hydrolysis ; hydroponics ; hydroxylation ; irrigation ; leaves ; liquid chromatography ; metabolites ; municipal wastewater ; screening ; tandem mass spectrometry ; tomatoes ; wastewater treatment
    Language English
    Dates of publication 2017-0606
    Size p. 6100-6109.
    Publishing place American Chemical Society
    Document type Article
    ISSN 1520-5851
    DOI 10.1021%2Facs.est.6b06485
    Database NAL-Catalogue (AGRICOLA)

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