Artikel ; Online: First case of Oropouche fever detected in the international border region of the Colombian Amazon: clinical characteristics and molecular diagnosis.
Memorias do Instituto Oswaldo Cruz
2024 Band 119, Seite(n) e230221
Abstract: Objectives: We report the first case of Oropouche fever detected in the border region of Colombia.: Methods: Using a multiplex real-time polymerase chain reaction (PCR), genetic sequencing and clinical characteristics during the dengue epidemic in ... ...
| Abstract | Objectives: We report the first case of Oropouche fever detected in the border region of Colombia. Methods: Using a multiplex real-time polymerase chain reaction (PCR), genetic sequencing and clinical characteristics during the dengue epidemic in 2019, a total of 175 samples were analysed, from cases notified to the system epidemiological surveillance such as dengue. Findings: The Oropouche virus (OROV) isolate from Leticia belongs to lineage 2 according to both M and S genome segments maximum likelihood (ML) analysis, shares a common ancestor with samples obtained in Esmeraldas, Ecuador and Turbaco, Colombia. The patient: a woman resident in the border neighbourhood of the municipality of Leticia had the following symptoms: fever, headache, retro-orbital pain and myalgias. Main conclusion: This cross-border surveillance can be useful to give an alert about the entry or exit of arboviruses circulation in the region, which are often underreported in public health surveillance systems. |
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| Mesh-Begriff(e) | Humans ; Female ; Colombia/epidemiology ; Orthobunyavirus/genetics ; Orthobunyavirus/isolation & purification ; Bunyaviridae Infections/diagnosis ; Bunyaviridae Infections/epidemiology ; Bunyaviridae Infections/virology ; Adult ; Real-Time Polymerase Chain Reaction ; Phylogeny |
| Sprache | Englisch |
| Erscheinungsdatum | 2024-05-13 |
| Erscheinungsland | Brazil |
| Dokumenttyp | Case Reports ; Journal Article |
| ZDB-ID | 953293-6 |
| ISSN | 1678-8060 ; 0074-0276 |
| ISSN (online) | 1678-8060 |
| ISSN | 0074-0276 |
| DOI | 10.1590/0074-02760230221 |
| Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
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