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  1. Artikel ; Online: 30 years with the Knee injury and Osteoarthritis Outcome Score (KOOS).

    Roos, Ewa M

    Osteoarthritis and cartilage

    2023  Band 32, Heft 4, Seite(n) 421–429

    Abstract: This narrative review describes the development and use of patient-reported outcomes over 30 years, focusing on the Knee injury and Osteoarthritis Outcome Score (KOOS). KOOS is a five-subscale patient-reported instrument intended for use from the time of ...

    Abstract This narrative review describes the development and use of patient-reported outcomes over 30 years, focusing on the Knee injury and Osteoarthritis Outcome Score (KOOS). KOOS is a five-subscale patient-reported instrument intended for use from the time of knee injury to the development of osteoarthritis. Numerous studies have confirmed that the psychometric properties of the KOOS and its short-form KOOS-12 are acceptable. More recent research has focused on the use and interpretation of KOOS scores in clinical trials using thresholds, such as minimal important differences, patient-acceptable symptom states, and treatment failure. As an indication of KOOS's popularity, the total 3854 PubMed results for KOOS have increased exponentially since the first KOOS paper was published 25 years ago and now seem to have plateaued at around 650 annually. The selected articles are not based on a systematic search, but on the author's own publications, reading, and literature search that grew organically from that.
    Mesh-Begriff(e) Humans ; Osteoarthritis, Knee/diagnosis ; Knee Injuries/diagnosis ; Treatment Failure ; Patient Reported Outcome Measures ; Psychometrics ; Quality of Life ; Treatment Outcome
    Sprache Englisch
    Erscheinungsdatum 2023-10-12
    Erscheinungsland England
    Dokumenttyp Journal Article ; Review
    ZDB-ID 1167809-4
    ISSN 1522-9653 ; 1063-4584
    ISSN (online) 1522-9653
    ISSN 1063-4584
    DOI 10.1016/j.joca.2023.10.002
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: 3 steps to improve reporting and interpretation of patient-reported outcome scores in orthopedic studies.

    Roos, Ewa M

    Acta orthopaedica

    2018  Band 89, Heft 1, Seite(n) 1–2

    Mesh-Begriff(e) Confidence Intervals ; Humans ; Knee Injuries/therapy ; Orthopedic Procedures/methods ; Orthopedic Procedures/standards ; Patient Reported Outcome Measures ; Quality Improvement ; Surveys and Questionnaires ; Treatment Outcome
    Sprache Englisch
    Erscheinungsdatum 2018
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2180677-9
    ISSN 1745-3682 ; 1745-3674
    ISSN (online) 1745-3682
    ISSN 1745-3674
    DOI 10.1080/17453674.2017.1407058
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  3. Artikel: Calculate Patient-Reported Scores as Recommended so as Not to Threaten the Validity of the Measure: Letter to the Editor.

    Roos, Ewa M

    Orthopaedic journal of sports medicine

    2018  Band 6, Heft 12, Seite(n) 2325967118816987

    Sprache Englisch
    Erscheinungsdatum 2018-12-31
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Comment
    ZDB-ID 2706251-X
    ISSN 2325-9671
    ISSN 2325-9671
    DOI 10.1177/2325967118816987
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  4. Artikel ; Online: Do self-reported knee instability, difficulty twisting, and knee confidence change after exercise and education in patients with knee osteoarthritis?

    Selçuk, Halit / Roos, Ewa M / Grønne, Dorte T / Thorlund, Jonas B / Sarı, Zübeyir / Skou, Søren T

    Musculoskeletal care

    2024  Band 22, Heft 2, Seite(n) e1884

    Mesh-Begriff(e) Humans ; Osteoarthritis, Knee/therapy ; Self Report ; Knee Joint ; Exercise ; Joint Instability ; Exercise Therapy
    Sprache Englisch
    Erscheinungsdatum 2024-04-18
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2171452-6
    ISSN 1557-0681 ; 1478-2189
    ISSN (online) 1557-0681
    ISSN 1478-2189
    DOI 10.1002/msc.1884
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  5. Artikel ; Online: Treatment for Acute Anterior Cruciate Ligament Tear in Young Active Adults.

    Lohmander, L Stefan / Roemer, Frank W / Frobell, Richard B / Roos, Ewa M

    NEJM evidence

    2023  Band 2, Heft 8, Seite(n) EVIDoa2200287

    Abstract: BACKGROUND: Anterior cruciate ligament (ACL) injury of the knee is common in young active adults and often has severe and sometimes lifelong consequences. The clinical management of this injury remains debated. A prior trial of early versus delayed ... ...

    Abstract BACKGROUND: Anterior cruciate ligament (ACL) injury of the knee is common in young active adults and often has severe and sometimes lifelong consequences. The clinical management of this injury remains debated. A prior trial of early versus delayed optional ACL repair showed no differences in outcomes at 2 years. METHODS: We present the 11-year follow-up of a randomized clinical trial involving 121 young active adults (mean age 26yo, 74% male) with an acute sports-related ACL tear. We compared patient-reported and radiographic outcomes between those randomized to receive early ACL reconstruction (ACLR) followed by exercise therapy (N=62) and those treated with early exercise therapy plus optional delayed ACLR (N=59). The primary end point at 11 years was change from baseline in the mean of four subscales of the Knee Injury and Osteoarthritis Outcome Score (KOOS) — pain, symptoms, function in sports and recreation, and knee-related quality of life (KOOS4; range of scores, 0 [worst] to 100 [best]; minimal important change=9). RESULTS: In all, 88% of the cohort followed up at 11 years (53/62 in the early vs. 54/59 in the optional late ACL repair groups), and 52% of those assigned to optional delayed ACLR underwent ACLR. Mean improvement in KOOS4 from baseline to 11 years was 46 points for those assigned to early ACLR plus exercise therapy and 45 points for those assigned to exercise therapy plus optional delayed ACLR (between-group difference, 1.6 points; 95% confidence interval [CI], −8.8 to 5.6; P=0.67 after adjustment for baseline score, full analysis set). About two thirds of the full cohort reported meeting the case definition for a “patient-acceptable symptom state” (KOOS4 patient-acceptable symptom state threshold value=79), whereas 44% had developed radiographic osteoarthritis of their injured knee. Mean summed incident radiographic osteoarthritis feature scores, scores range from 0 to 30 where higher scores indicate more severe joint damage, were 2.4 for the group assigned to early ACLR and 1.0 for the group assigned to exercise therapy plus optional delayed ACLR (mean difference, 1.0; 95% CI, 0.1 to 1.9). CONCLUSIONS: At 11-year follow-up, among young active adults with acute ACL tears assigned to early ACLR plus exercise versus initial exercise therapy with the option of delayed ACLR, there were no differences in patient-reported outcomes. (Funded by the Swedish Research Council; ISRCTN number, ISRCTN84752559.)
    Mesh-Begriff(e) Adult ; Humans ; Anterior Cruciate Ligament Injuries/surgery ; Anterior Cruciate Ligament/surgery ; Anterior Cruciate Ligament Reconstruction
    Sprache Englisch
    Erscheinungsdatum 2023-06-26
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 2766-5526
    ISSN (online) 2766-5526
    DOI 10.1056/EVIDoa2200287
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Foot and Ankle Outcome Score (FAOS): Reference Values From a National Representative Sample.

    Larsen, Peter / Rathleff, Michael S / Roos, Ewa M / Elsoe, Rasmus

    Foot & ankle orthopaedics

    2023  Band 8, Heft 4, Seite(n) 24730114231213369

    Abstract: Background: The Foot and Ankle Outcome Score (FAOS) is widely used in clinical practice and research. However, FAOS reference values are missing to aid interpretation. This study aimed to establish national record-based reference values for the FAOS.: ...

    Abstract Background: The Foot and Ankle Outcome Score (FAOS) is widely used in clinical practice and research. However, FAOS reference values are missing to aid interpretation. This study aimed to establish national record-based reference values for the FAOS.
    Methods: A national representative sample of 9996 adult Danish citizens was derived from the Danish Civil Registration System. The FAOS questionnaire was sent to all participants, including 2 supplemental questions regarding previous foot and ankle problems and body mass index (BMI). A threshold of 10 FAOS points was predefined as a clinically relevant difference across all 5 subscales.
    Results: A total of 2759 participants completed the FAOS. Mean age of participants was 60.5 years, and 51% were women. The mean FAOS subscale scores were as follows: pain, 87.1 (95% CI 86.4-87.8); symptoms, 85.1 (95% CI 84.5-85.8); activity of daily living (ADL), 88.9 (95% CI 88.2-89.6); sport and recreation function 78.5 (95% CI 77.4-79.6); and quality of life (QOL), 79.9 (95% CI 79.0-80.9). The mean difference between men and women was small and not clinically relevant (ranged from 0.9 in ADL to 3.4 in QOL). The largest differences in mean scores between age groups ranged from 4.3 in symptoms to 16.4 in sport/rec. Except for the subscale sport/rec, all age-related differences were below the predefined threshold of 10 for clinical relevance. The difference in mean subscale scores between the lowest BMI group (<24.7) and the obese group (>30) ranged from 19.6 in ADL to 39.1 in sport/rec.
    Conclusion: We found in our population that BMI severely impacted FAOS scores. We recommend using BMI-specific reference FAOS values. Separate FAOS reference values for men and women appear not needed. Stratifying reference values for age is likely not needed except for the subscale sport and recreation function.
    Level of evidence: Level III, cohort study.
    Sprache Englisch
    Erscheinungsdatum 2023-12-04
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 2473-0114
    ISSN (online) 2473-0114
    DOI 10.1177/24730114231213369
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  7. Artikel ; Online: National population-based reference data for the Hip Disability and Osteoarthritis Outcome Score (HOOS).

    Larsen, Peter / Rathleff, Michael S / Roos, Ewa M / Elsoe, Rasmus

    Archives of orthopaedic and trauma surgery

    2023  Band 143, Heft 11, Seite(n) 6865–6874

    Abstract: Introduction: Interpretation of patient-reported outcome scores such as the Hip Disability and Osteoarthritis Outcome Score (HOOS) can be improved with use of reference values. The aim of the study was to establish population-based reference values for ... ...

    Abstract Introduction: Interpretation of patient-reported outcome scores such as the Hip Disability and Osteoarthritis Outcome Score (HOOS) can be improved with use of reference values. The aim of the study was to establish population-based reference values for the HOOS' five subscales and its short-form HOOS-12.
    Materials and methods: A representative sample of 9997 Danish citizens 18 years and older were identified. The population record-based sample was based on seven predefined age groups and an equal sex distribution within each age group. A national secure electronic system was used to send the HOOS questionnaire and one supplementary question regarding previous hip complaints to all participants.
    Results: 2277 participants completed the HOOS, 947 women (42%) and 1330 men (58%). The mean HOOS subscale scores were: pain 86.9 (95% CI 86.1-87.7), symptoms 83.7 (95% CI 82.9-84.5), ADL 88.2 (95% CI 87.5-89.0), sport and recreation function 83.1 (95% CI 82.0-84.1), QOL 82.7 (95% CI 81.8-83.6). The youngest age group reported better mean scores in four subscales compared to the oldest age group (pain 91.7 vs. 84.5, mean difference 7.2 95% CI 0.4-14.0), (ADL 94.6 points vs. 83.2, mean difference 11.4 95% CI 4.9-17.8), (sport and recreation function 91.5 points vs. 73.8 points, mean difference 17.7 95% CI 9.0-26.4), (QOL 88.9 points vs. 78.8, mean difference 10.1 points 95% CI 2.0-18.2). Participants with a self-reported hip complaint had worse HOOS scores across all subscales (mean difference range 22.1-34.6). Super obese patients (BMI > 40) had > 12.5 points worse scores across the five HOOS subscales. Results were similar for the HOOS-12.
    Conclusion: This study provides reference values for the HOOS and its short form HOOS-12. Results show that older patients and patients with a BMI over 40 have worse HOOS and HOOS-12 scores that may be of clinical importance in the interpretation of scores both when evaluating potential for improvement and post-treatment results.
    Mesh-Begriff(e) Male ; Humans ; Female ; Osteoarthritis, Hip/surgery ; Quality of Life ; Pain ; Surveys and Questionnaires ; Patient Reported Outcome Measures ; Arthroplasty, Replacement, Hip/methods
    Sprache Englisch
    Erscheinungsdatum 2023-06-06
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 80407-1
    ISSN 1434-3916 ; 0003-9330 ; 0344-8444
    ISSN (online) 1434-3916
    ISSN 0003-9330 ; 0344-8444
    DOI 10.1007/s00402-023-04915-w
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  8. Artikel ; Online: Knee injury and osteoarthritis outcome score (KOOS) - National record-based reference values.

    Larsen, Peter / Rathleff, Michael S / Roos, Ewa M / Elsoe, Rasmus

    The Knee

    2023  Band 43, Seite(n) 144–152

    Abstract: Background: Knee Injury and Osteoarthritis Outcome Score (KOOS) and the short form KOOS-12 are commonly used in clinical practice and research but there are no national record-based reference values to aid interpretation. The aim of this study was to ... ...

    Abstract Background: Knee Injury and Osteoarthritis Outcome Score (KOOS) and the short form KOOS-12 are commonly used in clinical practice and research but there are no national record-based reference values to aid interpretation. The aim of this study was to establish national record-based reference values for the KOOS and its short form KOOS-12.
    Patients and methods: A national record-based representative sample of 9996 adult citizens were derived from the Danish Civil Registration System. The selection of citizens was based on seven predefined age groups with an equal sex distribution across each age strata. The KOOS questionnaire was sent to all participants, together with two supplemental questions regarding previous knee problems and body mass index (BMI).
    Results: A total of 2842 participants completed the KOOS, 1463 women (51.4%) and 1379 men (48.6%). The mean KOOS subscale scores were: pain 85.3 (95% confidence interval (CI): 84.6-85.9), symptoms 85.1 (95% CI: 84.5-85.8), activities of daily living (ADL) 86.7 (95% CI: 86.0-87.3), sport and recreation function 70.9 (95% CI: 69.8-72.0), quality of life (QOL) 74.9 (95% CI: 73.9-75.8).Age- and sex-specific reference values showed small differences in mean scores between the five KOOS subscales and all were below the threshold for clinically relevant improvement (10 points).Knee problems were associated with worse KOOS scores across all subscales. The difference in the mean subscale scores between the lowest (<24.9) and highest (>40) BMI groups ranged from 12.9 to 24.1. Comparable results were observed for KOOS-12.
    Conclusion: KOOS and KOOS-12 reference values can, in most situations, be used without stratification for age and sex. Sport/recreation reference values stratified for age and BMI may be of importance.
    Mesh-Begriff(e) Adult ; Male ; Humans ; Female ; Quality of Life ; Osteoarthritis, Knee/diagnosis ; Osteoarthritis, Knee/epidemiology ; Activities of Daily Living ; Reference Values ; Knee Injuries/diagnosis ; Knee Injuries/epidemiology
    Sprache Englisch
    Erscheinungsdatum 2023-07-04
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 1200476-5
    ISSN 1873-5800 ; 0968-0160
    ISSN (online) 1873-5800
    ISSN 0968-0160
    DOI 10.1016/j.knee.2023.06.004
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  9. Artikel ; Online: Online and onsite supervised exercise therapy and education for individuals with knee osteoarthritis - A before and after comparison of two different care delivery models.

    Holm, Paetur M / Roos, Ewa M / Grønne, Dorte T / Skou, Søren T

    Musculoskeletal care

    2023  Band 21, Heft 3, Seite(n) 878–889

    Abstract: Objective: To compare the 3 and 12-month changes on pain, function and quality of life between online and onsite delivery of Good Life with Osteoarthritis in Denmark (GLA:D: Design: Non-inferior comparison of individuals with knee OA receiving ... ...

    Abstract Objective: To compare the 3 and 12-month changes on pain, function and quality of life between online and onsite delivery of Good Life with Osteoarthritis in Denmark (GLA:D
    Design: Non-inferior comparison of individuals with knee OA receiving physiotherapist-supervised online (TeleGLA:D) or onsite (GLA:D®) (12 exercise and 2 education sessions). The primary outcome was the baseline-to-3-month change on KOOS-12 summary score. Secondary outcomes were changes in KOOS-12 subscales pain, function and quality of life and pain intensity (Visual Analog Scale (VAS 0-100)) at 3 and 12 months; 40 m fast-paced walk and 30 s chair-stand at 3 months. Using mixed linear regressions, comparisons were adjusted for age, sex, BMI, comorbidities and number of knees and hips with OA.
    Results: Over a 1-year period (May 2020-May 2021), we included data from 3789 participants (3701 GLA:D®; 88 TeleGLA:D). At 3 months, TeleGLA:D showed non-inferior change-scores to GLA:D® on KOOS-12 summary score; adjusted mean difference (90% Confidence Intervals (CI)) -2.40 (-5.55 to 0.75). For secondary outcomes, there was a statistically significant difference in change-scores, favouring TeleGLA:D in gait speed; adjusted mean difference (90%CI) 0.23 m/s (0.18-0.27). TeleGLA:D remained non-inferior to GLA:D® at 12 months.
    Conclusions: Online delivery of physiotherapist-supervised neuromuscular exercise and education for individuals with knee OA may be non-inferior to traditional onsite delivery in reducing pain and improving function and quality of life. The wide confidence intervals, baseline imbalance, loss to follow-up and the non-randomized design highlight the need for a confirmatory randomized controlled trial.
    Mesh-Begriff(e) Humans ; Osteoarthritis, Knee/therapy ; Quality of Life ; Exercise Therapy ; Exercise ; Pain
    Sprache Englisch
    Erscheinungsdatum 2023-04-04
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2171452-6
    ISSN 1557-0681 ; 1478-2189
    ISSN (online) 1557-0681
    ISSN 1478-2189
    DOI 10.1002/msc.1765
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  10. Artikel: Physical therapy for patients with knee and hip osteoarthritis: supervised, active treatment is current best practice study.

    Skou, Søren T / Roos, Ewa M

    Clinical and experimental rheumatology

    2020  Band 38, Heft 5, Seite(n) 1036

    Sprache Englisch
    Erscheinungsdatum 2020-10-02
    Erscheinungsland Italy
    Dokumenttyp Journal Article ; Published Erratum
    ZDB-ID 605886-3
    ISSN 1593-098X ; 0392-856X
    ISSN (online) 1593-098X
    ISSN 0392-856X
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