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  1. Artikel ; Online: Psychosis Treatment During COVID-19 Pandemic and the Potential Role of Phenothiazines: A Call for Research Studies.

    Ruiz de Pellón Santamaría, Ángel

    Journal of clinical psychopharmacology

    2020  Band 40, Heft 6, Seite(n) 641–642

    Mesh-Begriff(e) Antipsychotic Agents/pharmacokinetics ; Antipsychotic Agents/therapeutic use ; Betacoronavirus/drug effects ; Betacoronavirus/physiology ; Biological Availability ; Biomedical Research ; COVID-19 ; Chlorpromazine/pharmacokinetics ; Chlorpromazine/therapeutic use ; Coronavirus Infections/drug therapy ; Coronavirus Infections/metabolism ; Drug Repositioning/methods ; Humans ; Lung/drug effects ; Lung/metabolism ; Maximum Allowable Concentration ; Needs Assessment ; Pandemics ; Phenothiazines/pharmacokinetics ; Phenothiazines/therapeutic use ; Pneumonia, Viral/drug therapy ; Pneumonia, Viral/metabolism ; Psychotic Disorders/drug therapy ; SARS-CoV-2 ; Tissue Distribution
    Chemische Substanzen Antipsychotic Agents ; Phenothiazines ; Chlorpromazine (U42B7VYA4P)
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-11-01
    Erscheinungsland United States
    Dokumenttyp Letter
    ZDB-ID 604631-9
    ISSN 1533-712X ; 0271-0749
    ISSN (online) 1533-712X
    ISSN 0271-0749
    DOI 10.1097/JCP.0000000000001310
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel: Psychosis Treatment During COVID-19 Pandemic and the Potential Role of Phenothiazines: A Call for Research Studies

    Ruiz de Pellón Santamaría, Ángel

    J Clin Psychopharmacol

    Schlagwörter covid19
    Verlag WHO
    Dokumenttyp Artikel
    Anmerkung WHO #Covidence: #900622
    Datenquelle COVID19

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  3. Artikel ; Online: Psychosis Treatment During COVID-19 Pandemic and the Potential Role of Phenothiazines ; A Call for Research Studies

    Ruiz de Pellón Santamaría, Ángel

    Journal of Clinical Psychopharmacology

    2020  Band 40, Heft 6, Seite(n) 641–642

    Schlagwörter Pharmacology (medical) ; Psychiatry and Mental health ; covid19
    Sprache Englisch
    Verlag Ovid Technologies (Wolters Kluwer Health)
    Erscheinungsland us
    Dokumenttyp Artikel ; Online
    ZDB-ID 604631-9
    ISSN 1533-712X ; 0271-0749
    ISSN (online) 1533-712X
    ISSN 0271-0749
    DOI 10.1097/jcp.0000000000001310
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  4. Artikel ; Online: An overall protective effect of antipsychotic drugs against COVID-19 seems implausible.

    Ruiz de Pellón-Santamaría, Ángel / Sarasqueta-Eizaguirre, Cristina / Basterrechea-Peña, Francisco Javier

    Schizophrenia research

    2021  Band 243, Seite(n) 486–488

    Mesh-Begriff(e) Antipsychotic Agents/therapeutic use ; Bipolar Disorder/drug therapy ; COVID-19 ; Delayed-Action Preparations/therapeutic use ; Humans ; Schizophrenia/drug therapy
    Chemische Substanzen Antipsychotic Agents ; Delayed-Action Preparations
    Sprache Englisch
    Erscheinungsdatum 2021-12-22
    Erscheinungsland Netherlands
    Dokumenttyp Letter ; Comment
    ZDB-ID 639422-x
    ISSN 1573-2509 ; 0920-9964
    ISSN (online) 1573-2509
    ISSN 0920-9964
    DOI 10.1016/j.schres.2021.12.020
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel: Catatonia in older adults: A systematic review.

    Jaimes-Albornoz, Walter / Ruiz de Pellon-Santamaria, Angel / Nizama-Vía, Ayar / Isetta, Marco / Albajar, Ines / Serra-Mestres, Jordi

    World journal of psychiatry

    2022  Band 12, Heft 2, Seite(n) 348–367

    Abstract: Background: Catatonia is a complex psychomotor syndrome that often goes unrecognized and untreated, even though its classification has evolved in recent years. Prompt and correct identification of catatonia allows for highly effective treatment and ... ...

    Abstract Background: Catatonia is a complex psychomotor syndrome that often goes unrecognized and untreated, even though its classification has evolved in recent years. Prompt and correct identification of catatonia allows for highly effective treatment and prevention of possible complications. The underrecognition of catatonia in older patients is also frequent, and research in this population is scarce.
    Aim: To conduct a systematic review of the literature on catatonia in older people to ascertain its clinical characteristics across settings.
    Methods: Following the PRISMA guidelines, MEDLINE, EMBASE, and PsycINFO databases were searched from inception to December 2021, with a strategy aimed at identifying all articles published on catatonia in older adults. Titles and abstracts were scanned and selected independently by two authors. Papers investigating issues related to catatonia and/or catatonic symptoms in older people, with English abstracts available, were included. References of selected articles were revised to identify other relevant studies.
    Results: In total, 1355 articles were retrieved. After removing duplicates, 879 remained. Of the 879 identified abstracts, 669 were excluded because they did not meet the inclusion criteria. A total of 210 articles underwent full text review, and 51 were eliminated for various reasons. Fourteen more articles were selected from the references. Overall, 173 articles were reviewed: 108 case reports, 35 case series, 11 prospective cohort studies, 6 case-control studies, 3 retrospective cohort studies and 10 reviews. We found several particular aspects of catatonia in this population. Catatonia in older patients is highly prevalent and tends to have a multifactorial etiology. Older patients, compared to younger patients, have a higher risk of developing catatonia with benzodiazepine (BZD) withdrawal, in bipolar disorder, and in the general hospital. Age, together with other risk factors, was significantly associated with the incidence of deep venous thrombosis, neuroleptic malignant syndrome poor outcome, other complications and mortality. Treatment with BZDs and electroconvulsive therapy is safe and effective. Prompt treatment of its cause is essential to ensure a good prognosis.
    Conclusion: Catatonia in older patients is highly prevalent and tends to have a multifactorial etiology. The risk of developing catatonia in some settings and conditions, as well as of developing complications, is high in this population. Symptomatic treatment is safe and effective, and timely etiologic treatment is fundamental.
    Sprache Englisch
    Erscheinungsdatum 2022-02-19
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 2220-3206
    ISSN 2220-3206
    DOI 10.5498/wjp.v12.i2.348
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Antihistamine and cationic amphiphilic drugs, old molecules as new tools against the COVID-19?

    Gitahy Falcao Faria, Clara / Weiner, Luisa / Petrignet, Julien / Hingray, Coraline / Ruiz De Pellon Santamaria, Ángel / Villoutreix, Bruno O / Beaune, Philippe / Leboyer, Marion / Javelot, Hervé

    Medical hypotheses

    2021  Band 148, Seite(n) 110508

    Abstract: Several studies have reported that certain psychoactive drugs could have a protective effect against SARS-CoV-2. Herein, we propose that antihistamines (anti-H1) and cationic amphiphilic drugs (CAD), specifically, have the capacity to disrupt virus entry ...

    Abstract Several studies have reported that certain psychoactive drugs could have a protective effect against SARS-CoV-2. Herein, we propose that antihistamines (anti-H1) and cationic amphiphilic drugs (CAD), specifically, have the capacity to disrupt virus entry and replication. In addition, several of these molecules have limited side effects and as such could be promising prophylactic candidates against SARS-CoV-2 infection.
    Mesh-Begriff(e) COVID-19/drug therapy ; COVID-19/virology ; Drug Repositioning ; Histamine H1 Antagonists/pharmacology ; Humans ; Models, Biological ; Pandemics ; SARS-CoV-2/drug effects ; SARS-CoV-2/physiology ; Surface-Active Agents/pharmacology ; Virus Internalization/drug effects ; Virus Replication/drug effects
    Chemische Substanzen Histamine H1 Antagonists ; Surface-Active Agents
    Sprache Englisch
    Erscheinungsdatum 2021-01-24
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 193145-3
    ISSN 1532-2777 ; 0306-9877
    ISSN (online) 1532-2777
    ISSN 0306-9877
    DOI 10.1016/j.mehy.2021.110508
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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