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Artikel ; Online: The presence of extra chromosomes leads to genomic instability

Verena Passerini / Efrat Ozeri-Galai / Mirjam S. de Pagter / Neysan Donnelly / Sarah Schmalbrock / Wigard P. Kloosterman / Batsheva Kerem / Zuzana Storchová

Nature Communications, Vol 7, Iss 1, Pp 1-

2016  Band 12

Abstract: One of the hallmarks of cancer cells is aneuploidy, however the molecular effects are poorly understood. Here the authors show that trisomic and tetrasomic cells display increased genomic instability and reduced levels of the helicase MCM2-7. ...

Abstract One of the hallmarks of cancer cells is aneuploidy, however the molecular effects are poorly understood. Here the authors show that trisomic and tetrasomic cells display increased genomic instability and reduced levels of the helicase MCM2-7.
Schlagwörter Science ; Q
Sprache Englisch
Erscheinungsdatum 2016-02-01T00:00:00Z
Verlag Nature Portfolio
Dokumenttyp Artikel ; Online
Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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