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  1. Buch ; Dissertation / Habilitation: Expressionsanalyse Interferon-α-positiver und -negativer humaner plasmacytoider dendritischer Zellen

    Schneider, Linda

    (Edition Scientifique)

    2014  

    Verfasserangabe vorgelegt von Linda Schneider
    Serientitel Edition Scientifique
    Schlagwörter Dendritische Zelle ; Immunreaktion ; Cytokine ; Interferon ; Genexpression
    Schlagwörter Abwehrreaktion ; Immunantwort ; Immunoreaktivität ; Immunabwehr ; Zytokine
    Sprache Deutsch
    Ausgabenhinweis 1. Aufl.
    Verlag VVB Laufersweiler Verlag
    Erscheinungsort Gießen, Lahn
    Erscheinungsland Deutschland
    Dokumenttyp Buch ; Dissertation / Habilitation
    Dissertation / Habilitation Gießen, Univ., Diss., 2014
    HBZ-ID HT018195708
    ISBN 978-3-8359-6117-3 ; 3-8359-6117-9
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  2. Artikel ; Online: Made for TV, A Student Role-Playing Activity.

    Schneider, Linda

    Nurse educator

    2023  Band 49, Heft 1, Seite(n) 59

    Mesh-Begriff(e) Humans ; Nursing Education Research ; Television ; Students
    Sprache Englisch
    Erscheinungsdatum 2023-05-10
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 1034267-9
    ISSN 1538-9855 ; 0363-3624
    ISSN (online) 1538-9855
    ISSN 0363-3624
    DOI 10.1097/NNE.0000000000001452
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Buch ; Dissertation / Habilitation: Retrospektive Untersuchung freier mikrovaskulärer Lappenplastiken

    Schneider, Linda Sarah

    2009  

    Verfasserangabe vorgelegt von Linda Sarah Schneider
    Sprache Deutsch
    Umfang 88 Bl. : graph. Darst.
    Ausgabenhinweis [Mikrofiche-Ausg.]
    Erscheinungsland Deutschland
    Dokumenttyp Buch ; Dissertation / Habilitation
    Dissertation / Habilitation Freiburg (Breisgau), Univ., Diss., 2010
    HBZ-ID HT016830756
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  4. Buch ; Online: A 2D Sinogram-Based Approach to Defect Localization in Computed Tomography

    Zhou, Yuzhong / Schneider, Linda-Sophie / Fan, Fuxin / Maier, Andreas

    2024  

    Abstract: The rise of deep learning has introduced a transformative era in the field of image processing, particularly in the context of computed tomography. Deep learning has made a significant contribution to the field of industrial Computed Tomography. However, ...

    Abstract The rise of deep learning has introduced a transformative era in the field of image processing, particularly in the context of computed tomography. Deep learning has made a significant contribution to the field of industrial Computed Tomography. However, many defect detection algorithms are applied directly to the reconstructed domain, often disregarding the raw sensor data. This paper shifts the focus to the use of sinograms. Within this framework, we present a comprehensive three-step deep learning algorithm, designed to identify and analyze defects within objects without resorting to image reconstruction. These three steps are defect segmentation, mask isolation, and defect analysis. We use a U-Net-based architecture for defect segmentation. Our method achieves the Intersection over Union of 92.02% on our simulated data, with an average position error of 1.3 pixels for defect detection on a 512-pixel-wide detector.
    Schlagwörter Computer Science - Computer Vision and Pattern Recognition ; Electrical Engineering and Systems Science - Image and Video Processing
    Thema/Rubrik (Code) 006
    Erscheinungsdatum 2024-01-29
    Erscheinungsland us
    Dokumenttyp Buch ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  5. Buch ; Konferenzbeitrag: The psychology of human eating disorders

    Schneider, Linda H.

    preclinical and clinical perspectives ; [result of a Conference Entitled the Psychobiology of Human Eating Disorders, which was held in New York City on October 13 - 15, 1988]

    (Annals of the New York Academy of Sciences ; 575)

    1989  

    Titelvarianten The psychobiology of human eating disorders
    Veranstaltung/Kongress Conference Entitled the Psychobiology of Human Eating Disorders (1988, NewYorkNY)
    Verfasserangabe ed. by Linda H. Schneider
    Serientitel Annals of the New York Academy of Sciences ; 575
    Überordnung
    Schlagwörter Eating Disorders / psychology / congresses ; Essstörung ; Psychobiologie
    Schlagwörter Biologische Psychologie ; Essgewohnheit ; Essstörungen
    Sprache Englisch
    Umfang XII, 626 S. : Ill., graph. Darst.
    Erscheinungsort New York, NY
    Erscheinungsland Vereinigte Staaten
    Dokumenttyp Buch ; Konferenzbeitrag
    HBZ-ID HT003504393
    ISBN 0-89766-541-4 ; 0-89766-542-2 ; 978-0-89766-541-4 ; 978-0-89766-542-1
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  6. Artikel: Microglia-Derived Interleukin 23: A Crucial Cytokine in Alzheimer's Disease?

    Nitsch, Louisa / Schneider, Linda / Zimmermann, Julian / Müller, Marcus

    Frontiers in neurology

    2021  Band 12, Seite(n) 639353

    Abstract: Neuronal cell death, amyloid β plaque formation and development of neurofibrillary tangles are among the characteristics of Alzheimer's disease (AD). In addition to neurodegeneration, inflammatory processes such as activation of microglia and astrocytes ... ...

    Abstract Neuronal cell death, amyloid β plaque formation and development of neurofibrillary tangles are among the characteristics of Alzheimer's disease (AD). In addition to neurodegeneration, inflammatory processes such as activation of microglia and astrocytes are crucial in the pathogenesis and progression of AD. Cytokines are essential immune mediators of the immune response in AD. Recent data suggest a role of interleukin 23 (IL-23) and its p40 subunit in the pathogenesis of AD and corresponding animal models, in particular concerning microglia activation and amyloid β plaque formation. Moreover, in animal models, the injection of anti-p40 antibodies resulted in reduced amyloid β plaque formation and improved cognitive performance. Here, we discuss the pathomechanism of IL-23 mediated inflammation and its role in AD.
    Sprache Englisch
    Erscheinungsdatum 2021-04-07
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2564214-5
    ISSN 1664-2295
    ISSN 1664-2295
    DOI 10.3389/fneur.2021.639353
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Buch ; Online ; Dissertation / Habilitation: Expressionsanalyse Interferon-alpha-positiver und -negativer humaner plasmacytoider dendritischer Zellen

    Schneider, Linda

    (Edition scientifique)

    2014  

    Verfasserangabe Linda Schneider
    Serientitel Edition scientifique
    Sprache Deutsch
    Umfang Online-Ressource
    Verlag Universitätsbibliothek
    Erscheinungsort Gießen
    Dokumenttyp Buch ; Online ; Dissertation / Habilitation
    Dissertation / Habilitation Gießen, Justus-Liebig-Universität, Diss., 2014
    Anmerkung In: Giessen : VVB Laufersweiler
    Datenquelle Ehemaliges Sondersammelgebiet Küsten- und Hochseefischerei

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  8. Artikel ; Online: β-adrenergic signaling triggers enteric glial reactivity and acute enteric gliosis during surgery.

    Leven, Patrick / Schneider, Reiner / Schneider, Linda / Mallesh, Shilpashree / Vanden Berghe, Pieter / Sasse, Philipp / Kalff, Jörg C / Wehner, Sven

    Journal of neuroinflammation

    2023  Band 20, Heft 1, Seite(n) 255

    Abstract: Background: Enteric glia contribute to the pathophysiology of various intestinal immune-driven diseases, such as postoperative ileus (POI), a motility disorder and common complication after abdominal surgery. Enteric gliosis of the intestinal muscularis ...

    Abstract Background: Enteric glia contribute to the pathophysiology of various intestinal immune-driven diseases, such as postoperative ileus (POI), a motility disorder and common complication after abdominal surgery. Enteric gliosis of the intestinal muscularis externa (ME) has been identified as part of POI development. However, the glia-restricted responses and activation mechanisms are poorly understood. The sympathetic nervous system becomes rapidly activated by abdominal surgery. It modulates intestinal immunity, innervates all intestinal layers, and directly interfaces with enteric glia. We hypothesized that sympathetic innervation controls enteric glia reactivity in response to surgical trauma.
    Methods: Sox10
    Results: With ~ 4000 differentially expressed genes, the most substantial enteric glia response occurs early after intestinal manipulation. During POI, enteric glia switch into a reactive state and continuously shape their microenvironment by releasing inflammatory and migratory factors. Sympathetic denervation reduced the inflammatory response of enteric glia in the early postoperative phase. Optogenetic and pharmacological stimulation of β-adrenergic downstream signaling triggered enteric glial reactivity. Finally, distinct adrenergic agonists revealed β-1/2 adrenoceptors as the molecular targets of sympathetic-driven enteric glial reactivity.
    Conclusions: Enteric glia act as early responders during post-traumatic intestinal injury and inflammation. Intact sympathetic innervation and active β-adrenergic receptor signaling in enteric glia is a trigger of the immediate glial postoperative inflammatory response. With immune-activating cues originating from the sympathetic nervous system as early as the initial surgical incision, adrenergic signaling in enteric glia presents a promising target for preventing POI development.
    Mesh-Begriff(e) Animals ; Mice ; Gliosis ; Adrenergic Agents ; Neuroglia ; Signal Transduction ; Sympathetic Nervous System ; Enteric Nervous System
    Chemische Substanzen Adrenergic Agents
    Sprache Englisch
    Erscheinungsdatum 2023-11-08
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2156455-3
    ISSN 1742-2094 ; 1742-2094
    ISSN (online) 1742-2094
    ISSN 1742-2094
    DOI 10.1186/s12974-023-02937-0
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Buch ; Online: Data-Driven Filter Design in FBP

    Sun, Yipeng / Schneider, Linda-Sophie / Fan, Fuxin / Thies, Mareike / Gu, Mingxuan / Mei, Siyuan / Zhou, Yuzhong / Bayer, Siming / Maier, Andreas

    Transforming CT Reconstruction with Trainable Fourier Series

    2024  

    Abstract: In this study, we introduce a Fourier series-based trainable filter for computed tomography (CT) reconstruction within the filtered backprojection (FBP) framework. This method overcomes the limitation in noise reduction, inherent in conventional FBP ... ...

    Abstract In this study, we introduce a Fourier series-based trainable filter for computed tomography (CT) reconstruction within the filtered backprojection (FBP) framework. This method overcomes the limitation in noise reduction, inherent in conventional FBP methods, by optimizing Fourier series coefficients to construct the filter. This method enables robust performance across different resolution scales and maintains computational efficiency with minimal increment for the trainable parameters compared to other deep learning frameworks. Additionally, we propose Gaussian edge-enhanced (GEE) loss function that prioritizes the $L_1$ norm of high-frequency magnitudes, effectively countering the blurring problems prevalent in mean squared error (MSE) approaches. The model's foundation in the FBP algorithm ensures excellent interpretability, as it relies on a data-driven filter with all other parameters derived through rigorous mathematical procedures. Designed as a plug-and-play solution, our Fourier series-based filter can be easily integrated into existing CT reconstruction models, making it a versatile tool for a wide range of practical applications. Our research presents a robust and scalable method that expands the utility of FBP in both medical and scientific imaging.

    Comment: Preprint
    Schlagwörter Electrical Engineering and Systems Science - Image and Video Processing ; Computer Science - Computer Vision and Pattern Recognition ; Computer Science - Machine Learning
    Thema/Rubrik (Code) 006
    Erscheinungsdatum 2024-01-29
    Erscheinungsland us
    Dokumenttyp Buch ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  10. Artikel: Resolving Genotype-Phenotype Discrepancies of the Kidd Blood Group System Using Long-Read Nanopore Sequencing.

    Gueuning, Morgan / Thun, Gian Andri / Trost, Nadine / Schneider, Linda / Sigurdardottir, Sonja / Engström, Charlotte / Larbes, Naemi / Merki, Yvonne / Frey, Beat M / Gassner, Christoph / Meyer, Stefan / Mattle-Greminger, Maja P

    Biomedicines

    2024  Band 12, Heft 1

    Abstract: Due to substantial improvements in read accuracy, third-generation long-read sequencing holds great potential in blood group diagnostics, particularly in cases where traditional genotyping or sequencing techniques, primarily targeting exons, fail to ... ...

    Abstract Due to substantial improvements in read accuracy, third-generation long-read sequencing holds great potential in blood group diagnostics, particularly in cases where traditional genotyping or sequencing techniques, primarily targeting exons, fail to explain serological phenotypes. In this study, we employed Oxford Nanopore sequencing to resolve all genotype-phenotype discrepancies in the Kidd blood group system (JK, encoded by
    Sprache Englisch
    Erscheinungsdatum 2024-01-19
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines12010225
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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