Artikel ; Online: Epidemiologic Implication of the Association between Herpes Simplex Virus Infection and the Risk of Type 1 Diabetes Mellitus: A Nationwide Case-Control Study in Taiwan.
International journal of environmental research and public health
2022 Band 19, Heft 13
Abstract: Enterovirus infection is a known risk factor for type 1 diabetes (T1DM). Whether infection with other viruses induces T1DM remains undetermined. This study investigated the association between human herpesvirus (HHV) infection and the development of T1DM, ...
Abstract | Enterovirus infection is a known risk factor for type 1 diabetes (T1DM). Whether infection with other viruses induces T1DM remains undetermined. This study investigated the association between human herpesvirus (HHV) infection and the development of T1DM, using the data from Taiwan's National Health Insurance Research Database. Patients with T1DM and age- and sex-matched controls were included. Subjects with HHV infection were subgrouped into those with histories of varicella-zoster virus, herpes simplex virus (HSV), Epstein-Barr virus, and human cytomegalovirus infections. The odds ratio of the risk of T1DM was calculated using a multivariable conditional logistic regression model. Atopic diseases, autoimmune thyroid diseases, and history of enterovirus infection served as adjusted comorbidities. Our findings suggested a significant association between HSV infection and the risk of T1DM (adjusted odds ratio: 1.21; 95% CI: 1.01-1.47, |
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Mesh-Begriff(e) | Adolescent ; Case-Control Studies ; Diabetes Mellitus, Type 1/epidemiology ; Enterovirus Infections ; Epstein-Barr Virus Infections ; Herpes Simplex/complications ; Herpes Simplex/epidemiology ; Herpesviridae Infections ; Herpesvirus 1, Human ; Herpesvirus 4, Human ; Humans ; Taiwan/epidemiology |
Sprache | Englisch |
Erscheinungsdatum | 2022-06-26 |
Erscheinungsland | Switzerland |
Dokumenttyp | Journal Article ; Research Support, Non-U.S. Gov't |
ZDB-ID | 2175195-X |
ISSN | 1660-4601 ; 1661-7827 |
ISSN (online) | 1660-4601 |
ISSN | 1661-7827 |
DOI | 10.3390/ijerph19137832 |
Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
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