Artikel ; Online: Discovering Associations Between Acoustic Emission and Magnetic Resonance Imaging Biomarkers From 10 Osteoarthritic Knees.
IEEE transactions on bio-medical engineering
2022 Band 69, Heft 11, Seite(n) 3494–3503
Abstract: Objective: Acoustic emission (AE) sensed from knee joints during weight-bearing movements greatly increases with joint deterioration, but the relationship between AE patterns and specific anatomical damage, as seen for example in magnetic resonance ... ...
Abstract | Objective: Acoustic emission (AE) sensed from knee joints during weight-bearing movements greatly increases with joint deterioration, but the relationship between AE patterns and specific anatomical damage, as seen for example in magnetic resonance imaging (MRI), is unknown. This knowledge is essential to validate AE biomarkers for the evaluation of knee joints, and forms the objective of this exploratory work to associate knee AE and MRI. Methods: A novel processing framework is proposed to enable direct correlation between static 3D MRI of knees and their dynamic 1D AE during sit-stand-sit movements. It comprises a method to estimate articular cartilage thickness according to joint angle from knee MRI, and a method to derive statistically representative waveform features according to joint angle from movement and load-dependent knee AE. Results: In 10 subjects diagnosed with knee osteoarthritis, age 55∼79 years and body mass index 25∼35 kg/m Conclusion: AE provides promising quantitative biomarkers in knee joint disease. Significance: These findings provide impetus for the further development of AE as a low-cost non-invasive biomarker modality to improve the management of knee joint disease. |
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Mesh-Begriff(e) | Humans ; Aged ; Knee Joint/diagnostic imaging ; Osteoarthritis, Knee/diagnostic imaging ; Cartilage, Articular/diagnostic imaging ; Cartilage, Articular/pathology ; Magnetic Resonance Imaging/methods ; Acoustics ; Biomarkers |
Chemische Substanzen | Biomarkers |
Sprache | Englisch |
Erscheinungsdatum | 2022-10-19 |
Erscheinungsland | United States |
Dokumenttyp | Journal Article ; Research Support, Non-U.S. Gov't |
ZDB-ID | 160429-6 |
ISSN | 1558-2531 ; 0018-9294 |
ISSN (online) | 1558-2531 |
ISSN | 0018-9294 |
DOI | 10.1109/TBME.2022.3171493 |
Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
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