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  1. Buch: Differential diagnoses in surgical pathology: Breast

    Simpson, Jean F. / Sanders, Melinda E.

    (Differential diagnoses in surgical pathology)

    2017  

    Titelvarianten Breast
    Verfasserangabe Jean F. Simpson, Melinda E. Sanders
    Serientitel Differential diagnoses in surgical pathology
    Schlagwörter Breast Neoplasms / diagnosis ; Breast Neoplasms / pathology ; Diagnosis, Differential ; Pathology, Surgical / methods
    Sprache Englisch
    Umfang ix, 270 Seiten, Illustrationen
    Verlag Wolters Kluwer
    Erscheinungsort Philadelphia
    Erscheinungsland Vereinigte Staaten
    Dokumenttyp Buch
    Anmerkung Includes bibliographical references and index ; Zugang zur Online-Ausgabe über Code
    HBZ-ID HT019640041
    ISBN 978-1-4963-0065-2 ; 9781496375391 ; 1-4963-0065-3 ; 1496375394
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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    SignaturLeihstatusStandort
    2018 A 485 ausleihbar (Lesesaal) Lesesaal EG
    Zugang zur Online-Ausgabe über Code aus lizenzrechtlichen Gründen nicht verfügbar

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  2. Buch: Breast specimen radiography

    Rubin, Eva / Simpson, Jean F.

    needle localization and radiographic pathologic correlation

    1998  

    Verfasserangabe Eva Rubin ; Jean F. Simpson
    Sprache Englisch
    Umfang XII, 206 S. : zahlr. Ill.
    Verlag Lippincott-Raven
    Erscheinungsort Philadelphia u.a.
    Erscheinungsland Vereinigte Staaten
    Dokumenttyp Buch
    HBZ-ID HT008745367
    ISBN 0-3975-1667-3 ; 978-0-3975-1667-4
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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    Verfügbar in ZB MED Köln/Königswinter

    SignaturLeihstatusStandort
    1998 A 4821 bestellbar zur Ausleihe Magazin

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  3. Buch: Breast

    Simpson, Jean F / Sanders, Melinda E

    (Differential diagnoses in surgical pathology)

    2017  

    Verfasserangabe Jean F. Simpson, Melinda E. Sanders
    Serientitel Differential diagnoses in surgical pathology
    Mesh-Begriff(e) Breast Neoplasms/diagnosis ; Breast Neoplasms/pathology ; Diagnosis, Differential ; Pathology, Surgical/methods
    Sprache Englisch
    Umfang ix, 270 pages :, illustrations
    Dokumenttyp Buch
    ISBN 9781496300652 ; 1496300653
    Datenquelle Katalog der US National Library of Medicine (NLM)

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  4. Artikel: Update on atypical epithelial hyperplasia and ductal carcinoma in situ.

    Simpson, Jean F

    Pathology

    2008  Band 41, Heft 1, Seite(n) 36–39

    Abstract: Atypical ductal hyperplasia (ADH) as an indicator of increased risk for developing breast cancer is well established. Refinement in its molecular characterisation, especially as it relates to risk, continues to be challenging, largely because of its ... ...

    Abstract Atypical ductal hyperplasia (ADH) as an indicator of increased risk for developing breast cancer is well established. Refinement in its molecular characterisation, especially as it relates to risk, continues to be challenging, largely because of its small and very focal nature. Also a challenge is appropriate management of ADH when present on core biopsy. Additional support for ductal carcinoma in situ (DCIS) as a precursor to invasive cancer, as well as recent molecular characterisation of DCIS are presented. The importance of margin assessment in cases of DCIS and the limited role for sentinel lymph node biopsy in this setting are reviewed.
    Mesh-Begriff(e) Biopsy, Needle ; Breast Neoplasms/diagnosis ; Breast Neoplasms/epidemiology ; Breast Neoplasms/pathology ; Carcinoma, Intraductal, Noninfiltrating/diagnosis ; Carcinoma, Intraductal, Noninfiltrating/pathology ; Diagnosis, Differential ; Female ; Humans ; Hyperplasia/diagnosis ; Hyperplasia/pathology ; Risk Factors ; Sentinel Lymph Node Biopsy
    Sprache Englisch
    Erscheinungsdatum 2008-11-19
    Erscheinungsland England
    Dokumenttyp Journal Article ; Review
    ZDB-ID 7085-3
    ISSN 1465-3931 ; 0031-3025
    ISSN (online) 1465-3931
    ISSN 0031-3025
    DOI 10.1080/00313020802568097
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Volltext online

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  5. Artikel ; Online: Using hospital discharge data for injury research or surveillance? An observational study illustrating the impact of administrative change.

    Davie, Gabrielle / Barson, Dave / Simpson, Jean C / Lilley, Rebbecca / Gulliver, Pauline / Cryer, Colin

    Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention

    2019  Band 25, Heft 6, Seite(n) 540–545

    Abstract: Introduction: Hospital discharge data provide an important basis for determining priorities for injury prevention and monitoring trends in incidence. This study aims to illustrate the impact of a recent change in administrative practice on estimates of ... ...

    Abstract Introduction: Hospital discharge data provide an important basis for determining priorities for injury prevention and monitoring trends in incidence. This study aims to illustrate the impact of a recent change in administrative practice on estimates of hospitalised injury incidence and to investigate the extent to which different case selection affects trends in injury incidence rates.
    Methods: New Zealand (NZ) hospital discharges (2000-2014) with a primary diagnosis of injury were identified. Additional case selection criteria included first admissions only, and for serious injury, a high threat-to-life estimate. Comparisons were made, over time and by District Health Board, between hospitalised injury incidence estimates that included, or not, short-stay emergency department (SSED) discharges.
    Results: Of the 1 229 772 injury hospital discharges, 365 114 were SSED; 16% of the annual total in 2000, 38% in 2014. Identification of readmissions prior to the exclusion of SSED discharges resulted in 30 724 cases being erroneously removed. Age-standardised rates of hospitalised injury over the 15-year period increased by, on average, 2.7% per year when SSED discharges were included; there was minimal secular change (-0.2%) when SSEDs were excluded. For serious hospitalised injury, the annual increase was 2.3% when SSED was included compared with 1.1% when SSEDs were excluded.
    Conclusion: Spurious trends in hospitalised injury incidence can result when administrative practices are not appropriately accounted for. Exclusion of SSED discharges before the identification of readmissions and the use of a severity threshold are recommended to minimise the reporting bias in NZ hospitalised injury incidence estimates.
    Mesh-Begriff(e) Data Collection/statistics & numerical data ; Emergency Service, Hospital/statistics & numerical data ; Health Services Research ; Hospital Records/standards ; Hospitalization/statistics & numerical data ; Humans ; Incidence ; New Zealand/epidemiology ; Patient Discharge/statistics & numerical data ; Wounds and Injuries/epidemiology
    Sprache Englisch
    Erscheinungsdatum 2019-05-09
    Erscheinungsland England
    Dokumenttyp Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 1433667-4
    ISSN 1475-5785 ; 1353-8047
    ISSN (online) 1475-5785
    ISSN 1353-8047
    DOI 10.1136/injuryprev-2019-043201
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Artifactual Displacement of Ductal Carcinoma In Situ (ADDCIS) (Toothpaste Effect): A Mimicker of Invasive Ductal Carcinoma.

    Shabihkhani, Maryam / Simpson, Jean F / White, Marissa J / Cimino-Mathews, Ashley / Argani, Pedram

    The American journal of surgical pathology

    2019  Band 44, Heft 1, Seite(n) 120–128

    Abstract: Needle tract displacement is a recognized mimicker of invasive ductal carcinoma (IDC). Artifactual displacement of ductal carcinoma in situ (ADDCIS) unassociated with needle tracts may occur secondary to mechanical compression of breast specimens but has ...

    Abstract Needle tract displacement is a recognized mimicker of invasive ductal carcinoma (IDC). Artifactual displacement of ductal carcinoma in situ (ADDCIS) unassociated with needle tracts may occur secondary to mechanical compression of breast specimens but has not been systematically studied. We identified 16 cases of ADDCIS unassociated with needle tract changes; the majority (75%) were internal referrals to the breast pathology service to rule out IDC, 19% were received as external diagnostic consultations to rule out IDC, and 6% were routine second review cases originally diagnosed as IDC at an outside hospital. The majority (62.5%) of ADDCIS occurred in lumpectomies, whereas 25% occurred in mastectomies and 12.5% in core biopsies. ADDCIS foci ranged from <1 to 5 mm; however, all ADDCIS spanning >4 mm demonstrated a linear pattern of displacement. In all cases, ADDCIS involved mammary stroma in a nonlobular distribution; in half, ADDCIS extended between benign lobules. Immunohistochemistry revealed no myoepithelial cells around the ADDCIS (n=7), adding to the concern for IDC. However, in contrast to most IDC, ADDCIS lacked stromal reaction and showed degenerative, smudged chromatin. None of the 9 patients with significant follow-up (mean, 7 y) developed metastasis. All received further local therapy for DCIS (5 radiation, 4 completion mastectomy); 1 received adjuvant systemic therapy (hormone therapy for contralateral IDC). In conclusion, ADDCIS mimics IDC, particularly given its permeative pattern and absence of myoepithelial cells. ADDCIS is most common in lumpectomies but can occur in mastectomies or core biopsies. Diagnostic clues include smudged nuclear chromatin, lack of stromal response, and linear pattern of displacement in larger lesions. The benign follow-up without systemic therapy supports our view that ADDCIS does not represent true IDC.
    Mesh-Begriff(e) Adult ; Aged ; Artifacts ; Breast Neoplasms/pathology ; Carcinoma, Ductal, Breast/pathology ; Carcinoma, Intraductal, Noninfiltrating/pathology ; Diagnosis, Differential ; Female ; Humans ; Middle Aged ; Neoplasm Invasiveness ; Prospective Studies
    Sprache Englisch
    Erscheinungsdatum 2019-09-09
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 752964-8
    ISSN 1532-0979 ; 0147-5185
    ISSN (online) 1532-0979
    ISSN 0147-5185
    DOI 10.1097/PAS.0000000000001370
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1356: Hefte anzeigen Standort:
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  7. Artikel ; Online: The pathologist as a teacher.

    Simpson, Jean F / Washington, Kay

    American journal of clinical pathology

    2012  Band 138, Heft 3, Seite(n) 320

    Mesh-Begriff(e) Education, Medical, Graduate ; Fellowships and Scholarships ; Humans ; Internship and Residency ; Pathology/education
    Sprache Englisch
    Erscheinungsdatum 2012-09
    Erscheinungsland England
    Dokumenttyp Editorial
    ZDB-ID 2944-0
    ISSN 1943-7722 ; 0002-9173
    ISSN (online) 1943-7722
    ISSN 0002-9173
    DOI 10.1309/AJCPDUMLZI2LT1SB
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Preventing unintentional childhood injury at home: injury circumstances and interventions.

    Simpson, Jean C / Nicholls, Jane

    International journal of injury control and safety promotion

    2012  Band 19, Heft 2, Seite(n) 141–151

    Abstract: New Zealand's (NZ) preschoolers carry the greatest injury burden among children aged 0-14 years. These injuries commonly occur at home. To identify how NZ addresses child injury the 1990s national injury datasets and associated free text were examined ... ...

    Abstract New Zealand's (NZ) preschoolers carry the greatest injury burden among children aged 0-14 years. These injuries commonly occur at home. To identify how NZ addresses child injury the 1990s national injury datasets and associated free text were examined retrospectively, NZ injury circumstances and interventions were compared to internationally recognised hazards and best practice, and whether NZ interventions addressed common circumstances of injury was assessed. Certain injuries, often associated with activities of daily living, were not addressed by interventions, although most interventions advocated internationally are implemented in NZ. Possible reasons for main injuries not being addressed were the specificity and variable effectiveness of interventions, normality of many injury circumstances, difficulties in evaluating complex environments, and the need for active intervention. There is considerable scope for NZ to improve its child safety. It is unlikely that simple solutions will be found for complex circumstances in which injury events occur. Strategies to address multifaceted problems requiring changes to personal, social and societal factors are required, with evaluation methods able to match their complexity.
    Mesh-Begriff(e) Accidental Falls/prevention & control ; Accidents, Home/prevention & control ; Asphyxia/epidemiology ; Asphyxia/prevention & control ; Burns/epidemiology ; Burns/prevention & control ; Child, Preschool ; Drowning/epidemiology ; Drowning/prevention & control ; Health Promotion ; Humans ; New Zealand/epidemiology ; Poisoning/epidemiology ; Poisoning/prevention & control ; Public Policy ; Retrospective Studies ; Safety/legislation & jurisprudence ; Safety/standards ; Wounds and Injuries/epidemiology ; Wounds and Injuries/prevention & control
    Sprache Englisch
    Erscheinungsdatum 2012
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2011468-0
    ISSN 1745-7319 ; 0929-8347 ; 1387-3059 ; 1566-0974 ; 1745-7300
    ISSN (online) 1745-7319
    ISSN 0929-8347 ; 1387-3059 ; 1566-0974 ; 1745-7300
    DOI 10.1080/17457300.2011.635208
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Motorcyclists' perceptions and experiences of riding and risk and their advice for safety.

    Simpson, Jean C / Wilson, Suzanne / Currey, Nandika

    Traffic injury prevention

    2015  Band 16, Heft 2, Seite(n) 159–167

    Abstract: Objective: To examine the knowledge, observations, and perceptions of motorcycle riders on the risks of on-road motorcycling and potential safety measures to give insight and guidance in developing policies, programs, and legislation to improve the ... ...

    Abstract Objective: To examine the knowledge, observations, and perceptions of motorcycle riders on the risks of on-road motorcycling and potential safety measures to give insight and guidance in developing policies, programs, and legislation to improve the safety of motorcyclists.
    Methods: Individual and focus group interviews were conducted with dealers and a cross section of motorcyclists from selected regions across New Zealand. The interviews were analyzed and coded to identify common themes and diverse perspectives on why people rode motorcycles, riders' perceptions on risk, and possible safety strategies for on-road motorcycling.
    Findings and discussion: Motorcycling has major benefits for riders, although most riders perceived that the risks could be severe and they were susceptible to injury. Their observations on the threats and barriers to safety focused on 3 components: the rider, the motorcycle, and the environment. Risks included inexperience, not riding to the conditions, choice of motorcycle, protective clothing and conspicuity, and speed. The underlying risk of being on 2 wheels was accentuated by the availability of high-power motorcycles. The threats perceived in the environment included the behavior of other road users, especially car drivers, and the poor road conditions and surrounds encountered.
    Conclusions: Riders identified risks that have been recognized in the road safety literature as well as risks for which there are no engineering or scientific solutions. To effectively increase motorcyclist safety, recognition of the commonalities and the differences between motorcyclists' perspectives and proposed strategies is needed. This approach is more likely to engage riders and thus support positive behavior change among riders and drivers.
    Mesh-Begriff(e) Accidents, Traffic/prevention & control ; Focus Groups ; Humans ; Motorcycles ; New Zealand ; Qualitative Research ; Risk Assessment ; Risk-Taking ; Safety ; Wounds and Injuries/prevention & control
    Sprache Englisch
    Erscheinungsdatum 2015
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2089818-6
    ISSN 1538-957X ; 1538-9588
    ISSN (online) 1538-957X
    ISSN 1538-9588
    DOI 10.1080/15389588.2014.911852
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel: Can we know what to do when DCIS is diagnosed?

    Sanders, Melinda E / Simpson, Jean F

    Oncology (Williston Park, N.Y.)

    2011  Band 25, Heft 9, Seite(n) 852–856

    Abstract: Utilizing routine histopathologic parameters obtained from appropriately handled lumpectomy and mastectomy specimens, a rational therapeutic plan based on epidemiologic and outcome-based data can be devised for any patient diagnosed with ductal carcinoma ...

    Abstract Utilizing routine histopathologic parameters obtained from appropriately handled lumpectomy and mastectomy specimens, a rational therapeutic plan based on epidemiologic and outcome-based data can be devised for any patient diagnosed with ductal carcinoma in situ (DCIS). In order to make a sound decision when weighing the current treatment options for DCIS--which include excision alone, excision plus radiation, and mastectomy--the following are mandatory: 1) assurance of an accurate diagnosis, 2) assessment of DCIS size and grade, and 3) careful margin evaluation. Accurate grading of DCIS is critical, since high nuclear grade and the presence of necrosis are highly predictive of the inability to achieve adequate margins, of local recurrence, and of the probability of missed areas of invasion. Margin status is the single most important determinant of local control following breast conservation for DCIS; numerous studies have shown that as the margin width increases, the risk of local failure decreases. The pros and cons of irradiating conservatively treated patients with DCIS should be carefully weighed on a case-by-case basis. Despite the 20-year-old dogma that all patients treated with breast conservation should receive postoperative radiation, a subset of patients who can be successfully treated by excision alone has been identified.
    Mesh-Begriff(e) Biomarkers, Tumor/analysis ; Breast Neoplasms/diagnosis ; Breast Neoplasms/pathology ; Breast Neoplasms/therapy ; Carcinoma, Intraductal, Noninfiltrating/diagnosis ; Carcinoma, Intraductal, Noninfiltrating/pathology ; Carcinoma, Intraductal, Noninfiltrating/therapy ; Combined Modality Therapy ; Diagnosis, Differential ; Female ; Humans ; Sentinel Lymph Node Biopsy
    Chemische Substanzen Biomarkers, Tumor
    Sprache Englisch
    Erscheinungsdatum 2011-08
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 1067950-9
    ISSN 0890-9091
    ISSN 0890-9091
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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