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  1. Book: Polyneuropathien in der Praxis (mit Fallbeispielen)

    Wiethölter, Horst / Sommer, Norbert

    (UNI-MED science)

    2015  

    Author's details Prof. Dr. Horst Wiethölter, Prof. Dr. Norbert Sommer
    Series title UNI-MED science
    Keywords Polyneuropathie
    Subject Polyneuropathia ; PNP
    Subject code 616.856
    Language German
    Size 110 Seiten, Illustrationen, 25 cm
    Edition 1. Auflage
    Publisher UNI-MED Verlag AG
    Publishing place Bremen
    Publishing country Germany
    Document type Book
    HBZ-ID HT018914425
    ISBN 978-3-8374-2244-3 ; 3-8374-2244-5
    Database Catalogue ZB MED Medicine, Health

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  2. Book ; Thesis: Serumantikörper bei experimentell allergischer Neuritis

    Sommer, Norbert

    fluoreszenzopt. Unters

    1986  

    Size 77 S. : Ill., graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Tübingen, Univ., Diss., 1986
    HBZ-ID HT002898060
    Database Catalogue ZB MED Medicine, Health

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  3. Book: SPONTANE ODONTOGENE DYSPLASIE DER INCISIVI BEIM EUROPAEISCHEN FELDHAMSTER (CRICETUS CRICETUS LINNE)

    Sommer, Norbert

    1983  

    Title variant SPONTANE ODONTOGENE DYSPLASIE DER INCISIVI BEIM EUROPAEISCHEN FELDHAMSTER, CRICETUS CRICETUS LINNE
    Size 122 BL.
    Document type Book
    Note HANNOVER, MED. HOCHSCH., DISS., 1984
    HBZ-ID HT002679816
    Database Catalogue ZB MED Medicine, Health

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  4. Book ; Thesis: Einfluß von Geburtsgewicht und körperlicher Entwicklung auf Dentition und Gebißzustand

    Sommer, Birgit / Sommer, Norbert

    1983  

    Author's details vorgelegt von Birgit Sommer u. Norbert Sommer
    Size 144 Bl : graph. Darst.
    Publishing country XA-DDDE
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Jena, Univ., Diss., 1983
    HBZ-ID HT003090350
    Database Catalogue ZB MED Medicine, Health

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  5. Article: Coping as a resource to allow for psychosocial adjustment in fatal disease: results from patients with amyotrophic lateral sclerosis.

    Finsel, Julia / Rosenbohm, Angela / Peter, Raphael S / Bäzner, Hansjörg / Börtlein, Axel / Dempewolf, Silke / Schabet, Martin / Hecht, Martin / Kohler, Andreas / Opherk, Christian / Nägele, Andrea / Sommer, Norbert / Lindner, Alfred / Rothenbacher, Dietrich / Ludolph, Albert C / Nagel, Gabriele / Lulé, Dorothée E

    Frontiers in psychology

    2024  Volume 15, Page(s) 1361767

    Abstract: Background: Amyotrophic lateral sclerosis (ALS) is a fatal disorder, which imposes a severe emotional burden on patients. Appropriate coping mechanisms may alleviate this burden and facilitate wellbeing, with social support known to be a successful ... ...

    Abstract Background: Amyotrophic lateral sclerosis (ALS) is a fatal disorder, which imposes a severe emotional burden on patients. Appropriate coping mechanisms may alleviate this burden and facilitate wellbeing, with social support known to be a successful coping strategy. This observational study aimed to determine the interplay of general coping traits of hope for success and fear of failure, coping behavior of social activity, and patients' wellbeing.
    Methods: In this cross-sectional study, patients with ALS from a clinical-epidemiological registry in Southwestern Germany were interviewed regarding coping traits (achievement-motivated behavior: hope for success and fear of failure), coping behavior of social activity, and psychosocial adjustment, determined using measures of depressiveness, anxiety [both measured by Hospital Anxiety and Depression Scale (HADS)], and quality of life [Anamnestic Comparative Self-Assessment (ACSA)]. Demographics, clinical [ALS Functional Rating Scale revised version (ALSFRS-R)], and survival data were recorded.
    Results: A total of 868 patients [60.70% male patients, mean age: 64.70 (±10.83) years, mean ALSFRS-R: 37.36 ± 7.07] were interviewed. Anxiety in patients was found to be associated with a high fear of failure. In contrast, a generally positive attitude in patients exemplified in high hopes for success was associated with better wellbeing. Finally, coping behavior of social activity explained up to 65% of the variance of depressiveness among the patients with ALS.
    Conclusion: In this study, we present evidence that the wellbeing of patients with ALS is not an immediate fatalistic consequence of physical degradation but rather determined by coping traits and behavior, which may be trained to substantially increase the wellbeing of patients with ALS.
    Language English
    Publishing date 2024-04-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2024.1361767
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Multiple Sklerose — eine neuroimmunendokrine Erkrankung

    Sommer, Norbert

    Gehirn und Geschlecht

    Abstract: Die Multiple Sklerose (MS) ist eine chronische, entzündlich-demyelinisierende Erkrankung des Zentralnervensystems (ZNS), betrifft also Gehirn und Rückenmark, wobei heute eine autoimmune Ätiologie allgemein angenommen wird. Sie ist die häufigste ... ...

    Abstract Die Multiple Sklerose (MS) ist eine chronische, entzündlich-demyelinisierende Erkrankung des Zentralnervensystems (ZNS), betrifft also Gehirn und Rückenmark, wobei heute eine autoimmune Ätiologie allgemein angenommen wird. Sie ist die häufigste Entmarkungserkrankung des ZNS in Nordeuropa und Nordamerika (Prävalenz 1:1000) und die häufigste chronisch-neurologische Erkrankung, die bei jungen Erwachsenen zu bleibender Behinderung führt.
    Keywords covid19
    Publisher PMC
    Document type Article ; Online
    DOI 10.1007/978-3-540-71628-0_15
    Database COVID19

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  7. Article ; Online: Cystatin C based estimation of chronic kidney disease and amyotrophic lateral sclerosis in the ALS registry Swabia: associated risk and prognostic value.

    Nagel, Gabriele / Kurz, Deborah / Peter, Raphael S / Rosenbohm, Angela / Koenig, Wolfgang / Dupuis, Luc / Bäzner, Hansjörg / Börtlein, Axel / Dempewolf, Silke / Schabet, Martin / Hecht, Martin / Kohler, Andreas / Opherk, Christian / Naegele, Andrea / Sommer, Norbert / Lindner, Alfred / Tumani, Hayrettin / Ludolph, Albert C / Rothenbacher, Dietrich

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 19594

    Abstract: Kidney function as part of metabolic changes could be associated with amyotrophic lateral-sclerosis (ALS). We investigated the associations between estimated chronic kidney disease (CKD), based on the Chronic Kidney Disease Epidemiology Collaboration ( ... ...

    Abstract Kidney function as part of metabolic changes could be associated with amyotrophic lateral-sclerosis (ALS). We investigated the associations between estimated chronic kidney disease (CKD), based on the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) cystatin C equation, and the risk at onset and prognostic value of CKD for ALS. Between October 2010 and June 2014, 362 ALS cases (59.4% men, mean age 65.7 years) and 681 controls (59.5% men, means age 66.3 years) were included in a population-based case-control study based on the ALS registry Swabia in Southern Germany. All ALS cases were followed-up (median 89.7 months), 317 died. Serum samples were measured for cystatin C to estimate the glomerular filtration rate (eGFR) according to the CKD-EPI equation. Information on covariates were assessed by an interview-based standardized questionnaire. Conditional logistic regression models were applied to calculate odds ratios (OR) for risk of ALS associated with eGFR/CKD stages. Time-to-death associated with renal parameters at baseline was assessed in ALS cases only. ALS cases were characterized by lower body mass index, slightly lower smoking prevalence, more intense occupational work and lower education than controls. Median serum cystatin-C based eGFR concentrations were lower in ALS cases than in controls (54.0 vs. 59.5 mL/min pro 1.73 m
    MeSH term(s) Male ; Humans ; Aged ; Female ; Prognosis ; Amyotrophic Lateral Sclerosis ; Case-Control Studies ; Prospective Studies ; Cystatin C ; Renal Insufficiency, Chronic/complications ; Glomerular Filtration Rate ; Registries ; Creatinine ; Biomarkers
    Chemical Substances Cystatin C ; Creatinine (AYI8EX34EU) ; Biomarkers
    Language English
    Publishing date 2023-11-10
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-46179-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book: Überall Hass

    Sommer, Norbert

    Krisen, Kriege und Gewalt - Gründe und Auswege

    1994  

    Author's details hrsg. von Norbert Sommer
    Keywords Hass ; Gewalt
    Language German
    Size 530 S, 21 cm
    Publisher Wichern
    Publishing place Berlin
    Document type Book
    Note Includes bibliographical references and index
    ISBN 3889810640 ; 9783889810649
    Database Former special subject collection: coastal and deep sea fishing

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  9. Book: Der Traum aber bleibt

    Sommer, Norbert

    Sozialismus und christliche Hoffnung ; eine Zwischenbilanz

    1992  

    Author's details hrsg. von Norbert Sommer
    Keywords Christentum ; Sozialismus
    Language German
    Size 511 S., 21 cm
    Publisher Wichern
    Publishing place Berlin
    Document type Book
    ISBN 3889810535 ; 9783889810533
    Database Former special subject collection: coastal and deep sea fishing

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  10. Article ; Online: Stress, depression and antidepressant treatment options in patients suffering from multiple sclerosis.

    Schumann, Robert / Adamaszek, Michael / Sommer, Norbert / Kirkby, Kenneth C

    Current pharmaceutical design

    2012  Volume 18, Issue 36, Page(s) 5837–5845

    Abstract: Stress constitutes a risk factor for diseases where the immune system plays a significant role. Stress is recognized as a possible trigger for flare ups during the course of multiple sclerosis (MS). The disclosure to the patient of the diagnosis of MS, ... ...

    Abstract Stress constitutes a risk factor for diseases where the immune system plays a significant role. Stress is recognized as a possible trigger for flare ups during the course of multiple sclerosis (MS). The disclosure to the patient of the diagnosis of MS, the commencement of immunomodulatory therapy, and the unpredictability and vagaries of disease progression are all sources of stress. Biological stress systems such as the hypothalamic-pituitary-adrenal system and the sympathetic nervous system may influence the pathogenesis and the disease course of MS. The ability to cope with stress may also be impaired, mediated for example by cognitive deficits or loss of abilities and resources as disease progresses or by the high prevalence of concurrent mood disturbances such as depression and chronic fatigue. Psychiatric comorbidities of MS disease or therapy as well as impairments of coping strategies are underrecognized in clinical practice. Treatment plans for depression among MS patients, as the most common psychiatric comorbidity, should be individualized with integrated approaches. Antidepressants are effective for the treatment of depression in MS patients although further clinical research into the neurobiological and psychological bases of depressive disorders in MS patients is clearly needed. In therapy, coping strategies can be enhanced through multidisciplinary assessment of the various challenges and restrictions imposed by the disease and assisting and supporting the patient in addressing these. Exercise, as a form of positive stress (eustress), also has a role in therapy.
    MeSH term(s) Adaptation, Psychological ; Affect/drug effects ; Antidepressive Agents/adverse effects ; Antidepressive Agents/therapeutic use ; Cognition/drug effects ; Comorbidity ; Depression/diagnosis ; Depression/drug therapy ; Depression/epidemiology ; Depression/physiopathology ; Depression/psychology ; Exercise Therapy ; Humans ; Hypothalamo-Hypophyseal System/drug effects ; Hypothalamo-Hypophyseal System/physiopathology ; Multiple Sclerosis/epidemiology ; Multiple Sclerosis/physiopathology ; Multiple Sclerosis/psychology ; Pituitary-Adrenal System/drug effects ; Pituitary-Adrenal System/physiopathology ; Risk Factors ; Stress, Physiological/drug effects ; Stress, Psychological/epidemiology ; Stress, Psychological/physiopathology ; Stress, Psychological/psychology ; Sympathetic Nervous System/drug effects ; Sympathetic Nervous System/physiopathology ; Treatment Outcome
    Chemical Substances Antidepressive Agents
    Language English
    Publishing date 2012-05-24
    Publishing country United Arab Emirates
    Document type Journal Article ; Review
    ZDB-ID 1304236-1
    ISSN 1873-4286 ; 1381-6128
    ISSN (online) 1873-4286
    ISSN 1381-6128
    DOI 10.2174/138161212803523671
    Database MEDical Literature Analysis and Retrieval System OnLINE

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