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  1. Buch ; Online: Gleaming Coffins

    Sousa, Rogerio

    2018  

    Abstract: Egyptian coffin decoration is a complex and multidimensional phenomenon with its own history and evolution. 'Yellow' coffins were crafted in Thebes during a particular critical period in the Egyptian History, witnessing to a situation of political unrest ...

    Abstract Egyptian coffin decoration is a complex and multidimensional phenomenon with its own history and evolution. 'Yellow' coffins were crafted in Thebes during a particular critical period in the Egyptian History, witnessing to a situation of political unrest and severe economic scarcity affecting Egypt, the Near East and the Mediterranean. And yet, there is no evidence for a decline in the production of these outstanding funerary artefacts. On the contrary, the corpus of 'yellow' coffins outnumbers the previous types of Egyptian anthropoid containers and stands out among the most complex and sophisticated objects ever crafted in the Ancient World. Besides this historical paradox, the 'yellow' corpus presents important epistemological challenges for our understanding of Egyptian material culture: what kind of space is created within the walls and forms of an anthropoid coffin? What role plays variability and change in this process? Last but not the least, can we understand the meaning behind the multiple shapes and endless variations adopted in coffin decoration during this period? This book addresses these questions presenting the results of a comparative study on coffin decoration involving an extensive sample of objects from the 'yellow' corpus dispersed in museums around the world. The results of this study reveal the principles of composition that ruled the work of the ancient Theban craftsmen and show how important coffin decoration was for the Theban priesthood of Amun to convey their own corporative values
    Schlagwörter Agriculture
    Umfang 1 electronic resource (280 p.)
    Verlag Coimbra University Press
    Dokumenttyp Buch ; Online
    Anmerkung Portuguese ; Open Access
    HBZ-ID HT020103029
    ISBN 9789892615882 ; 9892615883
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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  2. Buch ; Online: Arbuscular Mycorrhizal Fungi in Agriculture

    Nogueira de Sousa, Rodrigo

    New Insights

    2023  

    Schlagwörter Medical microbiology & virology ; sustainable agriculture ; symbiosis ; biofertilizer ; diversity ; drought ; salinity
    Sprache Englisch
    Umfang 1 electronic resource (272 pages)
    Verlag IntechOpen
    Dokumenttyp Buch ; Online
    Anmerkung English
    HBZ-ID HT030381012
    ISBN 9781837680917 ; 1837680914
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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  3. Buch ; Online: Medicina à Cabeceira do Doente & Comunicação Clínica

    Sousa, Rita / Silva, Rui / Almeida, Marta / Pereira, Vitor Hugo / Sousa, Nuno

    2020  

    Schlagwörter Doctor/patient relationship ; Medicina clínica ; comunicação clínica
    Umfang 1 electronic resource (62 pages)
    Erscheinungsort Braga
    Dokumenttyp Buch ; Online
    Anmerkung Portuguese ; Open Access
    HBZ-ID HT021233278
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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  4. Artikel: Who Needs Values When We Have Valuing? Comments on Jean Moritz Müller,

    de Sousa, Ronald

    Emotion review : journal of the International Society for Research on Emotion

    2022  Band 14, Heft 4, Seite(n) 257–261

    Abstract: Müller argues that the perceptual or "Axiological Receptivity" (AR) model of emotions is incoherent, because it requires an emotion to apprehend and respond to its formal object at the same time. He defends a contrasting view of emotions as "Position- ... ...

    Abstract Müller argues that the perceptual or "Axiological Receptivity" (AR) model of emotions is incoherent, because it requires an emotion to apprehend and respond to its formal object at the same time. He defends a contrasting view of emotions as "Position-Takings" (PT) towards "formal objects", aspects of an emotion's target pertinent to the subject's concerns. I first cast doubt on the cogency of Müller's attack on AR as begging questions about the temporal characteristics of perceptual events. I then argue that Müller's version of PT is not radical enough. On my attitudinal view, formal objects are not values but natural properties that justify specific affective or behavioral responses. Values are constituted only by a negotiated social aggregation of individual evaluative attitudes.
    Sprache Englisch
    Erscheinungsdatum 2022-03-07
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2474844-4
    ISSN 1754-0747 ; 1754-0739
    ISSN (online) 1754-0747
    ISSN 1754-0739
    DOI 10.1177/17540739221085575
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: A Rare Presentation of Pica Disorder in Soap Ingestion Variant: Case Report and Review.

    Sousa, Rui / Cunha, Francisco / Abreu, Joana / Cunha, Nuno

    The Journal of nervous and mental disease

    2024  Band 212, Heft 2, Seite(n) 117–119

    Abstract: Abstract: Pica indicates the persistent ingestion of inedible substances over a period of at least 1 month, being discordant to the individual's cognitive development level and not directly attributable to cultural or social normative practices. The ... ...

    Abstract Abstract: Pica indicates the persistent ingestion of inedible substances over a period of at least 1 month, being discordant to the individual's cognitive development level and not directly attributable to cultural or social normative practices. The literature suggests that the prevalence of pica varies significantly according to the social and clinical context. It can co-occur with psychiatric disorders, with its etiology being poorly understood and most likely multifactorial. In this article, we report the case of a patient in her 50s with a clinical setting compatible with soap ingestion variant of pica disorder. In addition to the variety of ingested substances, pica can be associated with heterogeneous behavior, mainly of the obsessive-compulsive spectrum. Despite recent research, this condition is still a target of much speculation. This is a very rare and challenging presentation of a soap ingestion variant of pica with very few similar cases described to date.
    Mesh-Begriff(e) Female ; Humans ; Eating ; Pica/complications ; Pica/epidemiology ; Prevalence ; Soaps ; Middle Aged
    Chemische Substanzen Soaps
    Sprache Englisch
    Erscheinungsdatum 2024-01-30
    Erscheinungsland United States
    Dokumenttyp Case Reports ; Journal Article ; Review
    ZDB-ID 3020-x
    ISSN 1539-736X ; 0022-3018
    ISSN (online) 1539-736X
    ISSN 0022-3018
    DOI 10.1097/NMD.0000000000001716
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: A global synthesis of predation on bivalves.

    Meira, Alexandra / Byers, James E / Sousa, Ronaldo

    Biological reviews of the Cambridge Philosophical Society

    2024  Band 99, Heft 3, Seite(n) 1015–1057

    Abstract: Predation is a dominant structuring force in ecological communities. In aquatic environments, predation on bivalves has long been an important focal interaction for ecological study because bivalves have central roles as ecosystem engineers, basal ... ...

    Abstract Predation is a dominant structuring force in ecological communities. In aquatic environments, predation on bivalves has long been an important focal interaction for ecological study because bivalves have central roles as ecosystem engineers, basal components of food webs, and commercial commodities. Studies of bivalves are common, not only because of bivalves' central roles, but also due to the relative ease of studying predatory effects on this taxonomic group. To understand patterns in the interactions of bivalves and their predators we synthesised data from 52 years of peer-reviewed studies on bivalve predation. Using a systematic search, we compiled 1334 studies from 75 countries, comprising 61 bivalve families (N = 2259), dominated by Mytilidae (29% of bivalves), Veneridae (14%), Ostreidae (8%), Unionidae (7%), and Dreissenidae and Tellinidae (6% each). A total of 2036 predators were studied, with crustaceans the most studied predator group (34% of predators), followed by fishes (24%), molluscs (17%), echinoderms (10%) and birds (6%). The majority of studies (86%) were conducted in marine systems, in part driven by the high commercial value of marine bivalves. Studies in freshwater ecosystems were dominated by non-native bivalves and non-native predator species, which probably reflects the important role of biological invasions affecting freshwater biodiversity. In fact, while 81% of the studied marine bivalve species were native, only 50% of the freshwater species were native to the system. In terms of approach, most studies used predation trials, visual analysis of digested contents and exclusion experiments to assess the effects of predation. These studies reflect that many factors influence bivalve predation depending on the species studied, including (i) species traits (e.g. behaviour, morphology, defence mechanisms), (ii) other biotic interactions (e.g. presence of competitors, parasites or diseases), and (iii) environmental context (e.g. temperature, current velocity, beach exposure, habitat complexity). There is a lack of research on the effects of bivalve predation at the population and community and ecosystem levels (only 7% and 0.5% of studies respectively examined impacts at these levels). At the population level, the available studies demonstrate that predation can decrease bivalve density through consumption or the reduction of recruitment. At the community and ecosystem level, predation can trigger effects that cascade through trophic levels or effects that alter the ecological functions bivalves perform. Given the conservation and commercial importance of many bivalve species, studies of predation should be pursued in the context of global change, particularly climate change, acidification and biological invasions.
    Mesh-Begriff(e) Animals ; Bivalvia/physiology ; Predatory Behavior/physiology ; Food Chain ; Ecosystem
    Sprache Englisch
    Erscheinungsdatum 2024-01-31
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 1423558-4
    ISSN 1469-185X ; 0006-3231 ; 1464-7931
    ISSN (online) 1469-185X
    ISSN 0006-3231 ; 1464-7931
    DOI 10.1111/brv.13057
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Successful operational integration of healthcare analytics at Seattle Children's.

    Frisbee, Kathleen L / Sousa, Ryan

    Learning health systems

    2022  Band 7, Heft 2, Seite(n) e10331

    Abstract: Introduction: As the quantity and complexity of health data grows, it is critical for healthcare organizations to devise analytic strategies that power data innovation so they can take advantage of new opportunities and improve outcomes. Seattle ... ...

    Abstract Introduction: As the quantity and complexity of health data grows, it is critical for healthcare organizations to devise analytic strategies that power data innovation so they can take advantage of new opportunities and improve outcomes. Seattle Children's Healthcare System (Seattle Children's) is an example of an organization that has built an operating model that integrates analytics into their business and daily operations. We present a roadmap for how Seattle Children's consolidated its fragmented analytics operations into a unified cohesive ecosystem capable of supporting advanced analytics capabilities and operational integration to transform care and accelerate research.
    Methods: In-depth interviews were conducted with ten leaders at Seattle Children's who have been instrumental in developing their enterprise analytics program. Interviews included the following leadership roles: Chief Data & Analytics Officer, Director of Research Informatics, Principal Systems Architect, Manager of Bioinformatics and High Throughput Analytics, Director of Neurocritical Care, Strategic Program Manager & Neuron Product Development Lead, Director of Dev Ops,Director of Clinical Analytics, Data Science Manager, and Advance Analytics Product Engineer. The interviews were unstructured and consisted of conversations intended to gather information from leadership about their experiences in building out Enterprise Analytics at Seattle Children's.
    Results: Seattle Children's has built an advanced enterprise analytics ecosystem that is integrated into its daily operations by applying an entrepreneurial mindset and agile development practices that are common in a startup environment. Analytics efforts were approached iteratively by selecting high-value projects that were delivered through Multidisciplinary Delivery Teams that were integrated into service lines. Service line leadership, in partnership with the Delivery Team leads, were responsible for the success of the team by setting project priorities, determining project budgets, and maintaining overall governance of their analytics endeavors. This organizational structure has led to the development of a wide range of analytic products that have been used to improve both operations and clinical care at Seattle Children's.
    Conclusions: Seattle Children's has demonstrated how a leading healthcare system can successfully create a robust, scalable, near real-time analytics ecosystem- one that delivers significant value to the organization from the ever-expanding volume of health data we see today.
    Sprache Englisch
    Erscheinungsdatum 2022-08-19
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 2379-6146
    ISSN (online) 2379-6146
    DOI 10.1002/lrh2.10331
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Status epilepticus-Therapeutic management at the pediatric emergency department.

    Pais-Cunha, I / Valente, D / Abreu, D B / Fonseca, J / Melo, C / Sampaio, M / Santos, L A / Sousa, R

    Neurologia

    2024  Band 39, Heft 5, Seite(n) 426–431

    Abstract: Introduction: Status epilepticus is an important cause of pediatric neurological emergency. Immediate treatment is essential to prevent definitive neurological damage. Several antiepileptic drugs are available for the management of status epilepticus.!## ...

    Abstract Introduction: Status epilepticus is an important cause of pediatric neurological emergency. Immediate treatment is essential to prevent definitive neurological damage. Several antiepileptic drugs are available for the management of status epilepticus.
    Methods: Retrospective study of patients admitted at the emergency department of a tertiary hospital for 5 years (2014-2019). We analyzed the compliance to the treatment guidelines for pediatric status epilepticus.
    Results: One hundred and seventeen admissions were identified, 23.9% of these were febrile status epilepticus. Among the other cases, the most frequent cause was genetic (22.2%). The majority were convulsive status epilepticus (93.1%), 58.7% of which were generalized tonic-clonic seizures. Benzodiazepines were the most used first and second line drug (98.2% and 94.8%). The most frequent third drug used was diazepam (56.4%) followed by phenytoin (18.2%). An infra-therapeutic antiepileptic drug dose was given in 48.7% of cases. 49.6% presented with a prolonged status epilepticus and 6.8% needed intensive care. Incorrect sequence of drugs and infra-therapeutic doses were associated with prolonged status (p<0.001 and p<0.05) and an increased number of antiepileptic drugs used (p<0.001 and p<0.05).
    Conclusions: Benzodiazepines were the most frequently first and second line drugs used for status epilepticus management. Surprisingly, the most frequently third line drugs used were also benzodiazepines. These findings were partially explained by the misuse of infra-therapeutic doses of these drugs. Noncompliance with the implemented guidelines was associated with unfavorable outcomes.
    Mesh-Begriff(e) Humans ; Status Epilepticus/drug therapy ; Anticonvulsants/therapeutic use ; Retrospective Studies ; Female ; Male ; Emergency Service, Hospital ; Child ; Child, Preschool ; Infant ; Benzodiazepines/therapeutic use ; Guideline Adherence ; Adolescent ; Diazepam/therapeutic use
    Chemische Substanzen Anticonvulsants ; Benzodiazepines (12794-10-4) ; Diazepam (Q3JTX2Q7TU)
    Sprache Englisch
    Erscheinungsdatum 2024-05-16
    Erscheinungsland Spain
    Dokumenttyp Journal Article
    ZDB-ID 2654369-2
    ISSN 2173-5808 ; 2173-5808
    ISSN (online) 2173-5808
    ISSN 2173-5808
    DOI 10.1016/j.nrleng.2021.09.014
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel: Ceftriaxone-Induced Encephalopathy in a Patient With Chronic Kidney Disease.

    Martins, Ana Filipa / Dias, Mónica / Matos Sousa, Rita / Regadas, Maria João

    Cureus

    2024  Band 16, Heft 2, Seite(n) e54476

    Abstract: Neurotoxicity is an acknowledged side effect of third and fourth-generation cephalosporins, but its occurrence with ceftriaxone is not widely recognized. This article presents a case involving a 56-year-old woman with multiple comorbidities who sought ... ...

    Abstract Neurotoxicity is an acknowledged side effect of third and fourth-generation cephalosporins, but its occurrence with ceftriaxone is not widely recognized. This article presents a case involving a 56-year-old woman with multiple comorbidities who sought medical attention after experiencing lipothymia. The initial diagnosis suggested a urinary tract infection with acute kidney failure, leading to the initiation of ceftriaxone and hemodialysis. Subsequently, the patient exhibited a progressive deterioration of her neurological state, characterized by agitation and chorea. Metabolic encephalopathy, seizure/nonconvulsive status epilepticus, and acute central nervous system lesions were considered primary differential diagnoses, all of which were subsequently ruled out through thorough investigations. Days later, a remarkable recovery of the patient's neurological state was observed. A retrospective analysis revealed a correlation between the improvement and the fourth day of antimicrobial suspension. Consequently, a presumptive diagnosis of ceftriaxone-induced encephalopathy was made. This unusual case underscores the importance of recognizing the potential for pharmacological encephalopathy, particularly with ceftriaxone, and emphasizes its reversibility upon discontinuation of the implicated drug. Clinicians should remain vigilant to this uncommon adverse effect, promoting timely intervention and improved patient outcomes.
    Sprache Englisch
    Erscheinungsdatum 2024-02-19
    Erscheinungsland United States
    Dokumenttyp Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.54476
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel: Acute Encephalopathy in a 10-Year-Old Patient With Maple Syrup Urine Disease: A Challenging Diagnosis.

    Miragaia, Pedro / Grangeia, Ana / Rodrigues, Esmeralda / Sousa, Raquel / Ribeiro, Augusto

    Cureus

    2024  Band 16, Heft 1, Seite(n) e53043

    Abstract: Maple syrup urine disease (MSUD) is a rare autosomal recessive metabolic disorder characterized by a deficiency in the branched-chain alpha-keto acid dehydrogenase complex, leading to the toxic accumulation of leucine, isoleucine and valine. Acute ... ...

    Abstract Maple syrup urine disease (MSUD) is a rare autosomal recessive metabolic disorder characterized by a deficiency in the branched-chain alpha-keto acid dehydrogenase complex, leading to the toxic accumulation of leucine, isoleucine and valine. Acute encephalopathy (AE) is a severe neurological disorder with diverse etiologies, demanding prompt identification and intervention. We present a unique case of a previously healthy teenage patient who developed AE during an influenza infection. Despite initial inconclusive investigations, the patient's condition rapidly deteriorated, requiring pediatric intensive care unit (PICU) admission. Diagnostic challenges included fluctuating mental status and refractory intracranial hypertension, ultimately necessitating decompressive craniectomy. Empirical treatments, including corticosteroids, tocilizumab, and plasmapheresis, were administered. Finally, clinical exome analysis revealed a pathogenic variant in homozygosity in the BCKDHA gene associated with MSUD type Ia. Her adult sister, experiencing similar symptoms in the same time period, did not survive. This case underscores the importance of considering metabolic disorders in AE etiology, even accounting for its various associated syndromes and usual prolonged diagnostic investigation, as prompt treatment initiation is vital for improved outcomes. Management of AE involves addressing seizures, systemic support and neuromonitoring, namely, intracranial pressure monitoring. Inborn errors of metabolism, like MSUD, should be considered, even if universally screened, as delayed diagnosis can result in prolonged hospitalization and significant morbidity.
    Sprache Englisch
    Erscheinungsdatum 2024-01-27
    Erscheinungsland United States
    Dokumenttyp Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.53043
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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