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  1. Artikel ; Online: Health care utilization and outcomes in older adults after Traumatic Brain Injury: A CENTER-TBI study.

    van der Vlegel, Marjolein / Mikolić, Ana / Lee Hee, Quentin / Kaplan, Z L Rana / Retel Helmrich, Isabel R A / van Veen, Ernest / Andelic, Nada / Steinbuechel, Nicole V / Plass, Anne Marie / Zeldovich, Marina / Wilson, Lindsay / Maas, Andrew I R / Haagsma, Juanita A / Polinder, Suzanne

    Injury

    2022  Band 53, Heft 8, Seite(n) 2774–2782

    Abstract: Introduction: The incidence of Traumatic Brain Injury (TBI) is increasingly common in older adults aged ≥65 years, forming a growing public health problem. However, older adults are underrepresented in TBI research. Therefore, we aimed to provide an ... ...

    Abstract Introduction: The incidence of Traumatic Brain Injury (TBI) is increasingly common in older adults aged ≥65 years, forming a growing public health problem. However, older adults are underrepresented in TBI research. Therefore, we aimed to provide an overview of health-care utilization, and of six-month outcomes after TBI and their determinants in older adults who sustained a TBI.
    Methods: We used data from the prospective multi-center Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) study. In-hospital and post-hospital health care utilization and outcomes were described for patients aged ≥65 years. Ordinal and linear regression analyses were performed to identify determinants of the Glasgow Outcome Scale Extended (GOSE), health-related quality of life (HRQoL), and mental health symptoms six-months post-injury.
    Results: Of 1254 older patients, 45% were admitted to an ICU with a mean length of stay of 9 days. Nearly 30% of the patients received inpatient rehabilitation. In total, 554/1254 older patients completed the six-month follow-up questionnaires. The mortality rate was 9% after mild and 60% after moderate/severe TBI, and full recovery based on GOSE was reported for 44% of patients after mild and 6% after moderate/severe TBI. Higher age and increased injury severity were primarily associated with functional impairment, while pre-injury systemic disease, psychiatric conditions and lower educational level were associated with functional impairment, lower generic and disease-specific HRQoL and mental health symptoms.
    Conclusion: The rate of impairment and disability following TBI in older adults is substantial, and poorer outcomes across domains are associated with worse preinjury health. Nonetheless, a considerable number of patients fully or partially returns to their preinjury functioning. There should not be pessimism about outcomes in older adults who survive.
    Mesh-Begriff(e) Aged ; Brain Injuries, Traumatic ; Glasgow Outcome Scale ; Humans ; Patient Acceptance of Health Care ; Prospective Studies ; Quality of Life/psychology
    Sprache Englisch
    Erscheinungsdatum 2022-05-26
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 218778-4
    ISSN 1879-0267 ; 0020-1383
    ISSN (online) 1879-0267
    ISSN 0020-1383
    DOI 10.1016/j.injury.2022.05.009
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel: Cortical involvement in temporal reproduction: evidence for differential roles of the hemispheres.

    Kagerer, Florian A / Wittmann, Marc / Szelag, Elzbieta / Steinbüchel, Nicole v

    Neuropsychologia

    2001  Band 40, Heft 3, Seite(n) 357–366

    Abstract: Only few studies have addressed temporal processing for durations longer than 1 s, and even fewer studies have investigated cortical involvement in time perception, in particular temporal production and reproduction. The present study investigated ... ...

    Abstract Only few studies have addressed temporal processing for durations longer than 1 s, and even fewer studies have investigated cortical involvement in time perception, in particular temporal production and reproduction. The present study investigated temporal reproduction in healthy control subjects and patients with anterior or posterior cortical lesions in the left or right hemisphere, or with subcortical left-hemispheric lesions. The paradigm involved presentation of either auditory or visual stimuli of 10 different standard intervals ranging from 1 to 5.5 seconds duration. Participants were required to reproduce the duration of a stimulus. Our results show that: (1) temporal reproduction across this temporal range can be better described with two separate linear regressions (bilinear approach) than with one single linear regression, thus contrasting the scalar timing concept; (2) that patients can, regardless of the hemisphere lesioned, perform reproductions of durations smaller than 2-3 s with reasonable accuracy; and (3) that patients with right-hemispheric lesions appear to be impaired in reproductions of stimuli longer than 2-3 s. Since attention appeared not to be impaired in the patients tested, the findings suggest that the integrity of the right hemisphere seems to be critical for temporal reproduction of intervals longer than 2-3 s.
    Mesh-Begriff(e) Adult ; Aged ; Attention ; Brain Diseases/physiopathology ; Brain Diseases/psychology ; Cerebral Cortex/physiopathology ; Dominance, Cerebral ; Female ; Humans ; Male ; Middle Aged ; Task Performance and Analysis ; Time Perception
    Sprache Englisch
    Erscheinungsdatum 2001-09-11
    Erscheinungsland England
    Dokumenttyp Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 207151-4
    ISSN 1873-3514 ; 0028-3932
    ISSN (online) 1873-3514
    ISSN 0028-3932
    DOI 10.1016/s0028-3932(01)00111-7
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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