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  1. Buch ; Online ; Dissertation / Habilitation: Analyse von Frühveränderungen der Retina und ihre Assoziation zu diabetischen Veränderungen des kornealen Nervenfaserplexus bei Typ-2 Diabetes mellitus

    Steingrube, Nadine [Verfasser] / Guthoff, Rainer [Akademischer Betreuer] / Ringelstein, Marius [Gutachter]

    2024  

    Verfasserangabe Nadine Steingrube ; Gutachter: Marius Ringelstein ; Betreuer: Rainer Guthoff
    Schlagwörter Medizin, Gesundheit ; Medicine, Health
    Thema/Rubrik (Code) sg610
    Sprache Deutsch
    Verlag Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf
    Erscheinungsort Düsseldorf
    Dokumenttyp Buch ; Online ; Dissertation / Habilitation
    Datenquelle Digitale Dissertationen im Internet

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  2. Artikel ; Online: Immunoglobulin E-Selective Immunoadsorption Reduces Peripheral and Skin-Bound Immunoglobulin E and Modulates Cutaneous IL-13 Expression in Severe Atopic Dermatitis.

    Reich, Kristian / Hartjen, Anna / Reich, Jeremias / Schröder, Julie / Steingrube, Nadine / Bresch, Martina / Ertas, Beyhan / Falk, Thomas M / Blödorn-Schlicht, Norbert / Jäckle, Stefan / Meier, Markus

    The Journal of investigative dermatology

    2018  Band 139, Heft 3, Seite(n) 720–723

    Mesh-Begriff(e) Adult ; Aged ; Dermatitis, Atopic/therapy ; Disease Progression ; Female ; Humans ; Immunoglobulin E/immunology ; Immunoglobulin E/metabolism ; Immunomodulation ; Interleukin-13/genetics ; Interleukin-13/metabolism ; Male ; Middle Aged ; Pilot Projects ; Plasmapheresis/methods ; Severity of Illness Index ; Single-Chain Antibodies/genetics ; Single-Chain Antibodies/metabolism ; Skin/immunology ; T-Lymphocytes/immunology
    Chemische Substanzen Interleukin-13 ; Single-Chain Antibodies ; Immunoglobulin E (37341-29-0)
    Sprache Englisch
    Erscheinungsdatum 2018-10-24
    Erscheinungsland United States
    Dokumenttyp Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 80136-7
    ISSN 1523-1747 ; 0022-202X
    ISSN (online) 1523-1747
    ISSN 0022-202X
    DOI 10.1016/j.jid.2018.09.020
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: German Diabetes Study - Baseline data of retinal layer thickness measured by SD-OCT in early diabetes mellitus.

    Schröder, Katharina / Szendroedi, Julia / Benthin, Anna / Gontscharuk, Veronika / Ackermann, Philipp / Völker, Magdalena / Steingrube, Nadine / Nowotny, Bettina / Ziegler, Dan / Müssig, Karsten / Geerling, Gerd / Kuß, Oliver / Roden, Michael / Guthoff, Rainer

    Acta ophthalmologica

    2018  Band 97, Heft 2, Seite(n) e303–e307

    Abstract: Purpose: Recent studies highlighted that early diabetic neurodegeneration is present before microvascular changes are visible. Retinal neurodegeneration can decrease retinal layer thickness. We aimed to determine whether decreased retinal layer ... ...

    Abstract Purpose: Recent studies highlighted that early diabetic neurodegeneration is present before microvascular changes are visible. Retinal neurodegeneration can decrease retinal layer thickness. We aimed to determine whether decreased retinal layer thickness is present already in the early time course of disease.
    Methods: A cross-sectional analysis of patients and healthy adults from the German Diabetes Study (GDS, ClinicalTrials.gov Identifier number: CT01055093, https://clinicaltrials.gov/ct2/show/NCT01055093). Inclusion criteria were a diagnosis of diabetes mellitus (DM) within the last 12 months. Retinal layers thickness in the nasal pericentral segment was measured by spectral domain ocular coherence tomography (SD-OCT). For statistical analysis proc mixed (sas-version 9.4) was used.
    Results: One hundred and seventy-eight eyes of 89 patients with type 1 DM (58 males, age 36 ± 11 years, BMI 25.5 ± 4.2 kg/m²) and 242 eyes of 121 patients with type 2 DM (84 males, age 53 ± 10 years, BMI 31.9 ± 6.3 kg/m²) with a disease duration of less than 1 year were compared to 76 eyes of 38 controls (27 males, age 41 ± 16 years, BMI 27.3 ± 6.4 kg/m²). Analysis of retinal layer thickness and visual function did not reveal a significant difference between patients and controls.
    Conclusion: In the early course of DM potential, neurodegeneration does not relate to measureable changes of retinal layer thickness.
    Mesh-Begriff(e) Adolescent ; Adult ; Aged ; Cross-Sectional Studies ; Diabetes Mellitus, Type 1/complications ; Diabetes Mellitus, Type 1/epidemiology ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/epidemiology ; Diabetic Retinopathy/diagnosis ; Diabetic Retinopathy/epidemiology ; Diabetic Retinopathy/etiology ; Disease Progression ; Female ; Follow-Up Studies ; Germany/epidemiology ; Humans ; Incidence ; Male ; Middle Aged ; Prospective Studies ; Retinal Ganglion Cells/pathology ; Severity of Illness Index ; Time Factors ; Tomography, Optical Coherence/methods ; Visual Acuity ; Young Adult
    Sprache Englisch
    Erscheinungsdatum 2018-09-21
    Erscheinungsland England
    Dokumenttyp Journal Article ; Observational Study
    ZDB-ID 2408333-1
    ISSN 1755-3768 ; 1755-375X
    ISSN (online) 1755-3768
    ISSN 1755-375X
    DOI 10.1111/aos.13851
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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