Artikel ; Online: Effects of gender and body weight on fibroblast growth factor 23 responsiveness to estimated dietary phosphorus.
The journal of medical investigation : JMI
2016 Band 63, Heft 1-2, Seite(n) 58–62
Abstract: Fibroblast growth factor 23 (FGF23) is a molecule involved in regulating phosphorus homeostasis. Although some studies indicated an association between serum FGF23 levels and sex, the association has not been fully investigated. The purpose of this study ...
Abstract | Fibroblast growth factor 23 (FGF23) is a molecule involved in regulating phosphorus homeostasis. Although some studies indicated an association between serum FGF23 levels and sex, the association has not been fully investigated. The purpose of this study was to evaluate whether sex could influence FGF23 responsiveness to dietary phosphorus intake in healthy individuals. Thirty two healthy subjects between 21 and 28 years were recruited for this study. Subjects performed 24-hour urine collection and blood samples were collected. We estimated phosphorus intake (UC-P) from the urine collection (UC), and evaluated any association between UC-P and serum FGF23 levels. Subsequently, we compared serum FGF23 levels between males and females. Positive correlation was observed between UC-P and serum FGF23 levels. Serum FGF23 levels were significantly higher in males than in females. Serum FGF23 levels/UC-P was significantly higher in females than in males. There was no significant difference in serum FGF23 levels/UC-P/BW between the male and female groups. Our results indicate that there was no gender difference between FGF23 responsiveness to phosphorus intake per body weight. |
---|---|
Mesh-Begriff(e) | Adult ; Body Weight ; Female ; Fibroblast Growth Factors/blood ; Humans ; Male ; Phosphorus/urine ; Phosphorus, Dietary/administration & dosage ; Sex Characteristics ; Young Adult |
Chemische Substanzen | Phosphorus, Dietary ; fibroblast growth factor 23 ; Phosphorus (27YLU75U4W) ; Fibroblast Growth Factors (62031-54-3) |
Sprache | Englisch |
Erscheinungsdatum | 2016 |
Erscheinungsland | Japan |
Dokumenttyp | Journal Article ; Research Support, Non-U.S. Gov't |
ZDB-ID | 1435233-3 |
ISSN | 1349-6867 ; 1343-1420 |
ISSN (online) | 1349-6867 |
ISSN | 1343-1420 |
DOI | 10.2152/jmi.63.58 |
Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
Zusatzmaterialien
Kategorien
Verfügbar in ZB MED Köln/Königswinter
Zs.A 264: Hefte anzeigen | Standort: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG) |
Über subito bestellen
Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.