Artikel ; Online: Oral mucous membrane pemphigoid: updates in diagnosis and management.
2024 Band 236, Heft 4, Seite(n) 293–296
Abstract: Mucous membrane pemphigoid (MMP) is a rare, immune-mediated, vesiculobullous disease that predominantly affects the oral cavity and conjunctiva. In MMP, autoantibodies are directed against hemidesmosomal proteins in the basement membrane zone, most ... ...
| Abstract | Mucous membrane pemphigoid (MMP) is a rare, immune-mediated, vesiculobullous disease that predominantly affects the oral cavity and conjunctiva. In MMP, autoantibodies are directed against hemidesmosomal proteins in the basement membrane zone, most commonly BP180. Clinical signs and symptoms include gingival desquamation, erosions, and ulcerations. Differential diagnoses include other immune-mediated blistering diseases, such as bullous pemphigoid. Definitive diagnosis is reached through history taking, physical examination, tissue biopsy and/or serology testing. MMP, although not curable, is typically managed with topical or systemic corticosteroids, in addition to immunosuppressive therapies and biologic agents in recalcitrant cases. Untreated MMP can lead to life-threatening complications, such as blindness. As a condition that affects the oral cavity, it is important that dentists understand how to recognise, diagnose and manage the disease. |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mesh-Begriff(e) | Humans ; Pemphigoid, Bullous/diagnosis ; Pemphigoid, Bullous/drug therapy ; Pemphigoid, Benign Mucous Membrane/diagnosis ; Pemphigoid, Benign Mucous Membrane/drug therapy ; Oral Ulcer ; Autoantibodies/therapeutic use ; Mucous Membrane/pathology | ||||||||||
| Chemische Substanzen | Autoantibodies | ||||||||||
| Sprache | Englisch | ||||||||||
| Erscheinungsdatum | 2024-02-23 | ||||||||||
| Erscheinungsland | England | ||||||||||
| Dokumenttyp | Journal Article | ||||||||||
| ZDB-ID | 218090-x | ||||||||||
| ISSN | 1476-5373 ; 0007-0610 | ||||||||||
| ISSN (online) | 1476-5373 | ||||||||||
| ISSN | 0007-0610 | ||||||||||
| DOI | 10.1038/s41415-024-7064-x | ||||||||||
| Signatur |
|
||||||||||
| Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
Volltext online
Zusatzmaterialien
Kategorien
Verfügbar in ZB MED Köln/Königswinter
| Ul III Zs.143: Hefte anzeigen | Standort: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
|||
| Zs.MO 447: Hefte anzeigen |
Über subito bestellen
Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.