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Artikel: Advances in CMV Management: A Single Center Real-Life Experience.

Malagola, Michele / Pollara, Caterina / Polverelli, Nicola / Zollner, Tatiana / Bettoni, Daria / Gandolfi, Lisa / Gramegna, Doriana / Morello, Enrico / Turra, Alessandro / Corbellini, Silvia / Signorini, Liana / Moioli, Giovanni / Bernardi, Simona / Zanaglio, Camilla / Farina, Mirko / Testa, Tullio Elia / Caruso, Arnaldo / Russo, Domenico

Frontiers in cell and developmental biology

2020  Band 8, Seite(n) 534268

Abstract: CMV infection is a major challenge in allogeneic stem cell transplantation (allo-SCT). The changing landscape in CMV management includes the introduction of letermovir in prophylaxis of high-risk patients and the source of CMV DNA monitoring (plasma-PL ... ...

Abstract CMV infection is a major challenge in allogeneic stem cell transplantation (allo-SCT). The changing landscape in CMV management includes the introduction of letermovir in prophylaxis of high-risk patients and the source of CMV DNA monitoring (plasma-PL vs. whole blood-WB), for pre-emptive therapy (PET) initiation. We report here how our real-life experience in CMV management evolved, following letermovir registration. We focus on: (i) the effects of systematic use of letermovir for CMV prophylaxis in high-risk patients, (ii) the results of a longitudinal comparison of CMV DNAemia monitoring in PL and WB. From December 2018 to April 2020, 60 allo-SCTs have been performed in our center (LET
Sprache Englisch
Erscheinungsdatum 2020-10-27
Erscheinungsland Switzerland
Dokumenttyp Journal Article
ZDB-ID 2737824-X
ISSN 2296-634X
ISSN 2296-634X
DOI 10.3389/fcell.2020.534268
Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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