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  1. Artikel: Estimating deaths from foodborne disease in the UK for 11 key pathogens.

    Holland, Darren / Thomson, Laura / Mahmoudzadeh, Nazmina / Khaled, Abdul

    BMJ open gastroenterology

    2020  Band 7, Heft 1

    Abstract: Objective: To estimate the number of deaths from foodborne disease in the UK from 11 key pathogens.: Design: Four different models were developed using data from a range of sources. These included enhanced surveillance, outbreaks, death certificates ... ...

    Abstract Objective: To estimate the number of deaths from foodborne disease in the UK from 11 key pathogens.
    Design: Four different models were developed using data from a range of sources. These included enhanced surveillance, outbreaks, death certificates and hospital episode statistics data. For each model, median estimates were produced with 95% credible intervals (CrI). The results from the different models were compared.
    Results: The estimates for foodborne deaths for each pathogen from the different models were consistent, with CrIs largely overlapping. Based on the preferred model for each pathogen, foodborne norovirus is estimated to cause 56 deaths per year (95% CrI 32 to 92), foodborne
    Conclusions: We estimate that there are 180 deaths per year in the UK (95% CrI 113 to 359) caused by foodborne disease based on these 11 pathogens. While this is a small fraction of the estimated 2.4 million cases of foodborne illness per year it still illustrates the potential severity of these illnesses demonstrating the importance in continuing efforts to reduce these infections.
    Mesh-Begriff(e) Adenoviridae/isolation & purification ; Aged ; Aged, 80 and over ; Campylobacter/isolation & purification ; Clostridium perfringens/isolation & purification ; Cryptosporidium/isolation & purification ; Death Certificates ; Disease Outbreaks/statistics & numerical data ; Foodborne Diseases/epidemiology ; Foodborne Diseases/microbiology ; Foodborne Diseases/parasitology ; Foodborne Diseases/virology ; Giardia/isolation & purification ; Humans ; Listeria monocytogenes/isolation & purification ; Mamastrovirus/isolation & purification ; Mortality/trends ; Norovirus/isolation & purification ; Population Surveillance/methods ; Rotavirus/isolation & purification ; Salmonella/isolation & purification ; Severity of Illness Index ; Shigella/isolation & purification ; United Kingdom/epidemiology
    Sprache Englisch
    Erscheinungsdatum 2020-06-26
    Erscheinungsland England
    Dokumenttyp Comparative Study ; Journal Article
    ISSN 2054-4774
    ISSN 2054-4774
    DOI 10.1136/bmjgast-2020-000377
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel: Comparing simple albedo scaling methods for estimating Arctic glacier mass balance

    Williamson, Scott N / Copland, Luke / Thomson, Laura / Burgess, David

    Remote sensing of environment. 2020 Sept. 01, v. 246

    2020  

    Abstract: Mass balance measurements in the Canadian Arctic are limited, particularly for smaller glaciers, which introduces significant uncertainties in regional mass balance assessment. Here we report on the correlations between Moderate Resolution Imaging ... ...

    Abstract Mass balance measurements in the Canadian Arctic are limited, particularly for smaller glaciers, which introduces significant uncertainties in regional mass balance assessment. Here we report on the correlations between Moderate Resolution Imaging Spectroradiometer (MODIS) Terra albedo measurements (Version 6) and net annual mass balance for five glaciers in the Canadian Arctic over the period 2002–2016. Three glacier albedo aggregation methods are tested for the melt season (June, July and August): minimum, raw average, and interpolated average. These are evaluated in terms of a 53–71% reduction in observations due to cloud cover in the raw albedo time series. For the minimum method, the whole glacier albedo is calculated from the average of the minimum melt season albedo of each grid cell, irrespective of the day on which they occurred, resulting in R² values between 0.20 and 0.87. In the raw average method, averaging all albedo values within a glacier outline over the melt season improves the correlation to mass balance to a range of 0.61–0.95. In the interpolated average method, linear interpolation of the raw average albedo values to fill cloud gaps, then averaging them, improves the raw average correlations for all ice masses by ~5% (R² range 0.68–0.97). Overall, the interpolated average albedo method performs substantially better for the smallest glacier than the minimum or the raw average methods. The most negative net mass balance occurs at Grise Fiord Glacier, which is the smallest (<4.0 km²), but not the lowest elevation, glacier analysed. For this glacier, the interpolated average albedo improves the correlation with mass balance to an R² = 0.68 (p-value < .05), compared to an R² = 0.17 for the minimum albedo method (p-value > .05). When the five glaciers' interpolated average albedo is correlated to their ensemble mass balance, an R² = 0.82 is achieved. These results show that interpolated MODIS Terra melt season albedo measurements can realistically approximate net annual glacier mass balance for Arctic glaciers and ice caps, without additional information about precipitation or temperature, and in the absence of a melt model.
    Schlagwörter cloud cover ; environment ; glaciers ; ice ; models ; temperature ; time series analysis ; Arctic region
    Sprache Englisch
    Erscheinungsverlauf 2020-0901
    Erscheinungsort Elsevier Inc.
    Dokumenttyp Artikel
    Anmerkung NAL-AP-2-clean
    ZDB-ID 431483-9
    ISSN 0034-4257
    ISSN 0034-4257
    DOI 10.1016/j.rse.2020.111858
    Datenquelle NAL Katalog (AGRICOLA)

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  3. Artikel ; Online: Implementation of a risk mitigating COVID-adapted colorectal cancer pathway.

    Miller, Janice / Thomson, Laura J / Stewart, Lisa S P / Fleming, Jenny / Dunlop, Malcolm G / Din, Farhat V N / Maeda, Yasuko

    BMJ open quality

    2021  Band 10, Heft 1

    Mesh-Begriff(e) COVID-19 ; Colorectal Neoplasms ; Humans ; SARS-CoV-2
    Sprache Englisch
    Erscheinungsdatum 2021-01-08
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2399-6641
    ISSN (online) 2399-6641
    DOI 10.1136/bmjoq-2020-001135
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Prevalence of persistent SARS-CoV-2 in a large community surveillance study.

    Ghafari, Mahan / Hall, Matthew / Golubchik, Tanya / Ayoubkhani, Daniel / House, Thomas / MacIntyre-Cockett, George / Fryer, Helen R / Thomson, Laura / Nurtay, Anel / Kemp, Steven A / Ferretti, Luca / Buck, David / Green, Angie / Trebes, Amy / Piazza, Paolo / Lonie, Lorne J / Studley, Ruth / Rourke, Emma / Smith, Darren L /
    Bashton, Matthew / Nelson, Andrew / Crown, Matthew / McCann, Clare / Young, Gregory R / Santos, Rui Andre Nunes Dos / Richards, Zack / Tariq, Mohammad Adnan / Cahuantzi, Roberto / Barrett, Jeff / Fraser, Christophe / Bonsall, David / Walker, Ann Sarah / Lythgoe, Katrina

    Nature

    2024  Band 626, Heft 8001, Seite(n) 1094–1101

    Abstract: Persistent SARS-CoV-2 infections may act as viral reservoirs that could seed future ... ...

    Abstract Persistent SARS-CoV-2 infections may act as viral reservoirs that could seed future outbreaks
    Mesh-Begriff(e) Humans ; Amino Acid Substitution ; Antibodies, Monoclonal/immunology ; COVID-19/epidemiology ; COVID-19/virology ; Evolution, Molecular ; Health Surveys ; Immunocompromised Host/immunology ; Mutation ; Persistent Infection/epidemiology ; Persistent Infection/virology ; Post-Acute COVID-19 Syndrome/epidemiology ; Post-Acute COVID-19 Syndrome/virology ; Prevalence ; RNA, Viral/analysis ; RNA, Viral/genetics ; SARS-CoV-2/chemistry ; SARS-CoV-2/classification ; SARS-CoV-2/genetics ; SARS-CoV-2/immunology ; SARS-CoV-2/isolation & purification ; Selection, Genetic ; Self Report ; Time Factors ; Viral Load ; Virus Replication
    Chemische Substanzen Antibodies, Monoclonal ; RNA, Viral
    Sprache Englisch
    Erscheinungsdatum 2024-02-21
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/s41586-024-07029-4
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Buch: PHP and MySQL Web development

    Welling, Luke / Thomson, Laura

    (Developer's library)

    2009  

    Verfasserangabe Luke Welling; Laura Thomson
    Serientitel Developer's library
    Schlagwörter Web sites/Design
    Sprache Englisch
    Umfang XXXIV, 968 S, Ill, 24 cm
    Ausgabenhinweis 4th ed
    Verlag Addison-Wesley
    Erscheinungsort Upper Saddle River, NJ u.a.
    Dokumenttyp Buch
    Anmerkung Includes bibliographical references (p. [907]-910) and index ; The book's companion CD-ROM contains full versions of PHP, MySQL, Apache, several graphics libraries, files containing the code listings in the book, and the entire book in PDF format
    Begleitmaterial 1 CD-ROM (12 cm)
    ISBN 0672329166 ; 9780672329166
    Datenquelle Katalog der Technische Informationsbibliothek Hannover

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  6. Buch: PHP 5.3 & MySQL 5.1

    Welling, Luke / Thomson, Laura

    dynamische Webanwendungen von Einstieg bis E-Commerce

    (Kompendium)

    2009  

    Titelübersetzung PHP and MySQL web development <dt.>
    Verfasserangabe Luke Welling; Laura Thomson. [Übers.: Christian Alkemper]
    Serientitel Kompendium
    Schlagwörter MySQL 5.1 ; PHP 5.3
    Sprache Deutsch
    Umfang 1023 S., Ill., graph. Darst., 25 cm
    Verlag Markt+Technik-Verl
    Erscheinungsort München
    Dokumenttyp Buch
    Anmerkung Transl. from the Engl. language ed., 4. ed.
    Begleitmaterial 1 DVD-ROM
    ISBN 9783827243904 ; 3827243904
    Datenquelle Katalog der Technische Informationsbibliothek Hannover

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  7. Buch ; Online: Housing construction cycles and interest rates

    Berger-Thomson, Laura / Ellis, Luci

    (Research discussion paper / Economic Group, Reserve Bank of Australia ; 2004-08)

    2004  

    Verfasserangabe Laura Berger-Thomson and Luci Ellis
    Serientitel Research discussion paper / Economic Group, Reserve Bank of Australia ; 2004-08
    Sprache Englisch
    Umfang Online Ressource, 186 KB, text
    Verlag Reserve Bank of Australia, Economic Group
    Erscheinungsort Sydney
    Dokumenttyp Buch ; Online
    Anmerkung IMD-Felder maschinell generiert ; Record-last-verified: 22-06-05
    Datenquelle ECONomics Information System

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  8. Buch: PHP 5 & MySQL 5

    Welling, Luke / Thomson, Laura

    dynamische Webanwendungen von Einstieg bis E-Commerce

    (Kompendium)

    2007  

    Verfasserangabe Luke Welling; Laura Thomson
    Serientitel Kompendium
    Schlagwörter PHP 5.0 ; MySQL 5.0
    Sprache Deutsch
    Umfang 949 S, Ill., graph. Darst., 24 cm
    Verlag Markt + Technik Verl
    Erscheinungsort München
    Dokumenttyp Buch
    Begleitmaterial 1 CD-ROM
    ISBN 3827242991 ; 9783827242990
    Datenquelle Katalog der Technische Informationsbibliothek Hannover

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  9. Artikel ; Online: Oxidative deoxyribonucleic acid damage in sperm has a negative impact on clinical pregnancy rate in intrauterine insemination but not intracytoplasmic sperm injection cycles.

    Thomson, Laura Kelly / Zieschang, Julie-Anne / Clark, Anne Melton

    Fertility and sterility

    2011  Band 96, Heft 4, Seite(n) 843–847

    Abstract: Objective: To determine the level of DNA damage, both fragmentation and oxidative, in the sperm population used for intrauterine insemination (IUI) and intracytoplasmic sperm injection (ICSI) and its impact on fertilization and clinical pregnancy rates.! ...

    Abstract Objective: To determine the level of DNA damage, both fragmentation and oxidative, in the sperm population used for intrauterine insemination (IUI) and intracytoplasmic sperm injection (ICSI) and its impact on fertilization and clinical pregnancy rates.
    Design: A prospective clinical study.
    Setting: A tertiary care fertility clinic.
    Patient(s): Couples undergoing ICSI (n = 48) and couples undergoing IUI cycles (n = 53).
    Intervention(s): Assessment of both sperm DNA fragmentation using the TUNEL assay and oxidative DNA damage using the biomarker 8-hydroxy-2'-deoxyguanosine (8-OHdG) in the samples prepared and used for insemination.
    Main outcome measure(s): Achievement of a clinical pregnancy.
    Result(s): Sperm DNA fragmentation and 8-OHdG were highly correlated (r = 0.55) and 8-OHdG was significantly lower in those who achieved a clinical pregnancy after IUI (8.9% vs. 20.2%). A threshold value of 11.5% 8-OHdG was identified as a useful predictor of IUI success. No differences were found in sperm DNA fragmentation or 8-OHdG between pregnant and nonpregnant couples in ICSI cycles.
    Conclusion(s): 8-Hydroxy-2'-deoxyguanosine, a biomarker of oxidative DNA damage highly correlated with sperm DNA fragmentation, in human sperm DNA has significant value in predicting the chance of a clinical pregnancy after IUI but not ICSI in assisted reproductive technology.
    Mesh-Begriff(e) Adult ; DNA/chemistry ; DNA/genetics ; DNA/metabolism ; DNA Damage/physiology ; DNA Fragmentation ; Deoxyguanosine/analogs & derivatives ; Deoxyguanosine/analysis ; Female ; Humans ; Insemination, Artificial, Homologous/trends ; Male ; Oxidative Stress/physiology ; Pregnancy ; Pregnancy Rate/trends ; Prospective Studies ; Sperm Injections, Intracytoplasmic/trends ; Spermatozoa/metabolism
    Chemische Substanzen 8-oxo-7-hydrodeoxyguanosine (88847-89-6) ; DNA (9007-49-2) ; Deoxyguanosine (G9481N71RO)
    Sprache Englisch
    Erscheinungsdatum 2011-10
    Erscheinungsland United States
    Dokumenttyp Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80133-1
    ISSN 1556-5653 ; 0015-0282
    ISSN (online) 1556-5653
    ISSN 0015-0282
    DOI 10.1016/j.fertnstert.2011.07.356
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel ; Online: Correction: Viral burden is associated with age, vaccination, and viral variant in a population-representative study of SARS-CoV-2 that accounts for time-since-infection-related sampling bias.

    Fryer, Helen R / Golubchik, Tanya / Hall, Matthew / Fraser, Christophe / Hinch, Robert / Ferretti, Luca / Thomson, Laura / Nurtay, Anel / Pellis, Lorenzo / House, Thomas / MacIntyre-Cockett, George / Trebes, Amy / Buck, David / Piazza, Paolo / Green, Angie / Lonie, Lorne J / Smith, Darren / Bashton, Matthew / Crown, Matthew /
    Nelson, Andrew / McCann, Clare M / Tariq, Mohammed Adnan / Elstob, Claire J / Dos Santos, Rui Nunes / Richards, Zack / Xhang, Xin / Hawley, Joseph / Lee, Mark R / Carrillo-Barragan, Priscilla / Chapman, Isobel / Harthern-Flint, Sarah / Bonsall, David / Lythgoe, Katrina A

    PLoS pathogens

    2023  Band 19, Heft 10, Seite(n) e1011706

    Abstract: This corrects the article DOI: 10.1371/journal.ppat.1011461.]. ...

    Abstract [This corrects the article DOI: 10.1371/journal.ppat.1011461.].
    Sprache Englisch
    Erscheinungsdatum 2023-10-06
    Erscheinungsland United States
    Dokumenttyp Published Erratum
    ZDB-ID 2205412-1
    ISSN 1553-7374 ; 1553-7374
    ISSN (online) 1553-7374
    ISSN 1553-7374
    DOI 10.1371/journal.ppat.1011706
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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