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  1. Artikel ; Online: Bone involvement in non-congenital syphilis

    Trujillo, Daniela / Agudelo, Carlos Andrés / Chavarriaga, Andrés / Villa, Pablo / Vélez, Alejandro / Cardona, Ricardo / Hidrón, Alicia

    Biomedica : revista del Instituto Nacional de Salud

    2023  Band 43, Heft 2, Seite(n) 157–163

    Abstract: We documented two stages of bone involvement due to syphilis in two adult patients infected with human immunodeficiency virus. Bony lesions of secondary versus tertiary syphilis cannot be differentiated on clinical or radiologic grounds alone. Given the ... ...

    Titelübersetzung Compromiso óseo por sífilis no congénita
    Abstract We documented two stages of bone involvement due to syphilis in two adult patients infected with human immunodeficiency virus. Bony lesions of secondary versus tertiary syphilis cannot be differentiated on clinical or radiologic grounds alone. Given the rarity of this clinical presentation, there is no consensus on treatment duration and related outcomes.
    Mesh-Begriff(e) Adult ; Humans ; Syphilis/complications ; Syphilis/diagnosis ; Bone Diseases ; Consensus
    Sprache Spanisch
    Erscheinungsdatum 2023-06-30
    Erscheinungsland Colombia
    Dokumenttyp Journal Article
    ZDB-ID 2059952-3
    ISSN 2590-7379 ; 2590-7379
    ISSN (online) 2590-7379
    ISSN 2590-7379
    DOI 10.7705/biomedica.6603
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: An optimized nucleic acid isolation protocol for virus diagnostics in cassava (Manihot esculenta Crantz.)

    Jimenez, Jenyfer / Leiva, Ana Maria / Olaya, Cristian / Acosta-Trujillo, Daniela / Cuellar, Wilmer Jose

    MethodsX. 2021, v. 8 p.101496-

    2021  

    Abstract: Our group works on the detection and characterization of cassava viruses, supporting projects that involve large scale pathogen surveillance activities and resistance screening assays in multiple and remote locations. In order to comply with these ... ...

    Abstract Our group works on the detection and characterization of cassava viruses, supporting projects that involve large scale pathogen surveillance activities and resistance screening assays in multiple and remote locations. In order to comply with these applications, nucleic acid isolation protocols need to be cost effective, adjusted for samples that will stand long distance transport and harsh storage conditions, while maximizing the yield and quality of the nucleic acid extracts obtained. The method we describe here has been widely used and validated using different downstream tests (including, but not limited to, Rolling Circle Amplification and Illumina and Nanopore sequencing), but is currently unpublished. The protocol begins with milligram amounts of dry leaf samples stored in silica gel, does not require liquid Nitrogen nor phenol extraction and produces an average of 2.11 µg of nucleic acids per mg of dry tissue.•DNA purity estimations reveal OD260/280 ratios above 2.0 and OD260/230 ratios above 1.7, even for samples stored in silica gel for several months.•The high quality of the extracts is suitable for detection of DNA and RNA viruses, with high efficiency.•We suggest this method could be used as part of a gold standard kit for virus detection in cassava.
    Schlagwörter DNA ; Manihot esculenta ; RNA ; cassava ; cost effectiveness ; diagnostic techniques ; leaves ; liquid nitrogen ; monitoring ; pathogens ; phenol ; silica gel ; viruses ; CTAB extraction ; Disease surveillance ; Begomovirus ; Potexvirus ; Nucleic acid extraction protocol for the detection and characterization of cassava-infecting viruses
    Sprache Englisch
    Erscheinungsort Elsevier B.V.
    Dokumenttyp Artikel ; Online
    ZDB-ID 2830212-6
    ISSN 2215-0161
    ISSN 2215-0161
    DOI 10.1016/j.mex.2021.101496
    Datenquelle NAL Katalog (AGRICOLA)

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  3. Artikel ; Online: Effectiveness of combining prevention psychological interventions with interventions that address the social determinants of mental health in low and middle-income countries: protocol of a systematic review and meta-analysis.

    Prina, Eleonora / Bano, Beatrice / Singh, Rakesh / Albanese, Emiliano / Trujillo, Daniela / Dedios Sanguineti, María Cecilia / Sorsdahl, Katherine / Luitel, Nagendra P / Garman, Emily C / Purgato, Marianna / Barbui, Corrado / Jordans, Mark J D / Lund, Crick

    BMJ open

    2024  Band 14, Heft 5, Seite(n) e083261

    Abstract: Introduction: Common mental health conditions (CMHCs), including depression, anxiety and post-traumatic stress disorder (PTSD), are highly prevalent in low and middle-income countries (LMICs). Preventive strategies combining psychological interventions ... ...

    Abstract Introduction: Common mental health conditions (CMHCs), including depression, anxiety and post-traumatic stress disorder (PTSD), are highly prevalent in low and middle-income countries (LMICs). Preventive strategies combining psychological interventions with interventions addressing the social determinants of mental health may represent a key strategy for effectively preventing CMHCs. However, no systematic reviews have evaluated the effectiveness of these combined intervention strategies for preventing CMHCs.
    Methods and analysis: This systematic review will include randomised controlled trials (RCTs) focused on the effectiveness of interventions that combine preventive psychological interventions with interventions that address the social determinants of mental health in LMICs. Primary outcome is the frequency of depression, anxiety or PTSD at postintervention as determined by a formal diagnostic tool or any other standardised criteria. We will search Epistemonikos, Cochrane Controlled Trials Register (CENTRAL), MEDLINE, Embase, PsycINFO, CINAHL, Global Index Medicus, ClinicalTrials.gov (Ctgov), International Clinical Trials Registry Platform (ICTRP). Two reviewers will independently extract the data and evaluate the risk of bias of included studies using the Cochrane risk of bias tool 2. Random-effects meta-analyses will be performed, and certainty of evidence will be rated using the Grading of Recommendations Assessment, Development and Evaluation approach.
    Ethics and dissemination: This study uses data from published studies; therefore, ethical review is not required. Findings will be presented in a published manuscript.
    Trial registration number: CRD42023451072.
    Mesh-Begriff(e) Humans ; Systematic Reviews as Topic ; Developing Countries ; Social Determinants of Health ; Research Design ; Psychosocial Intervention/methods ; Stress Disorders, Post-Traumatic/prevention & control ; Meta-Analysis as Topic ; Mental Health ; Depression/prevention & control ; Mental Disorders/prevention & control ; Mental Disorders/therapy ; Anxiety/prevention & control ; Randomized Controlled Trials as Topic
    Sprache Englisch
    Erscheinungsdatum 2024-05-16
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2023-083261
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel: An optimized nucleic acid isolation protocol for virus diagnostics in cassava (

    Jimenez, Jenyfer / Leiva, Ana Maria / Olaya, Cristian / Acosta-Trujillo, Daniela / Cuellar, Wilmer Jose

    MethodsX

    2021  Band 8, Seite(n) 101496

    Abstract: Our group works on the detection and characterization of cassava viruses, supporting projects that involve large scale pathogen surveillance activities and resistance screening assays in multiple and remote locations. In order to comply with these ... ...

    Abstract Our group works on the detection and characterization of cassava viruses, supporting projects that involve large scale pathogen surveillance activities and resistance screening assays in multiple and remote locations. In order to comply with these applications, nucleic acid isolation protocols need to be cost effective, adjusted for samples that will stand long distance transport and harsh storage conditions, while maximizing the yield and quality of the nucleic acid extracts obtained. The method we describe here has been widely used and validated using different downstream tests (including, but not limited to, Rolling Circle Amplification and Illumina and Nanopore sequencing), but is currently unpublished. The protocol begins with milligram amounts of dry leaf samples stored in silica gel, does not require liquid Nitrogen nor phenol extraction and produces an average of 2.11 µg of nucleic acids per mg of dry tissue.•DNA purity estimations reveal OD260/280 ratios above 2.0 and OD260/230 ratios above 1.7, even for samples stored in silica gel for several months.•The high quality of the extracts is suitable for detection of DNA and RNA viruses, with high efficiency.•We suggest this method could be used as part of a gold standard kit for virus detection in cassava.
    Sprache Englisch
    Erscheinungsdatum 2021-08-21
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 2830212-6
    ISSN 2215-0161
    ISSN 2215-0161
    DOI 10.1016/j.mex.2021.101496
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: An optimized nucleic acid isolation protocol for virus diagnostics in cassava (Manihot esculenta Crantz.)

    Jiménez Polo, Jenyfer / Leiva, Ana Maria / Olaya, Cristian A. / Acosta-Trujillo, Daniela / Cuéllar, Wilmer Jose

    MethodsX

    2022  

    Abstract: Our group works on the detection and characterization of cassava viruses, supporting projects that involve large scale pathogen surveillance activities and resistance screening assays in multiple and remote locations. In order to comply with these ... ...

    Abstract Our group works on the detection and characterization of cassava viruses, supporting projects that involve large scale pathogen surveillance activities and resistance screening assays in multiple and remote locations. In order to comply with these applications, nucleic acid isolation protocols need to be cost effective, adjusted for samples that will stand long distance transport and harsh storage conditions, while maximizing the yield and quality of the nucleic acid extracts obtained. The method we describe here has been widely used and validated using different downstream tests (including, but not limited to, Rolling Circle Amplification and Illumina and Nanopore sequencing), but is currently unpublished. The protocol begins with milligram amounts of dry leaf samples stored in silica gel, does not require liquid Nitrogen nor phenol extraction and produces an average of 2.11 µg of nucleic acids per mg of dry tissue.
    Schlagwörter nucleic acids ; diagnostic techniques ; methods ; acidos nucléicos ; técnicas de diagnosis ; métodos
    Sprache Englisch
    Erscheinungsdatum 2022-08-25T07:39:11Z
    Verlag Elsevier
    Erscheinungsland fr
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Volltext online

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  6. Artikel ; Online: New Coordination Polymers of Copper(I) and Silver(I) with Pyrazine and Piperazine: A Step Toward "Green" Chemistry and Optoelectronic Applications.

    Almotawa, Ruaa M / Aljomaih, Ghadah / Trujillo, Daniela Vargas / Nesterov, Vladimir N / Rawashdeh-Omary, Manal A

    Inorganic chemistry

    2018  Band 57, Heft 16, Seite(n) 9962–9976

    Abstract: Five coordination polymers and one hexanuclear cluster have been obtained, and their crystal structures were determined upon reaction of Cu(I) or Ag(I) precursors with pyrazine (Pyz) or piperazine (Ppz). Five complexes are mixed-imine-ligand with anionic- ...

    Abstract Five coordination polymers and one hexanuclear cluster have been obtained, and their crystal structures were determined upon reaction of Cu(I) or Ag(I) precursors with pyrazine (Pyz) or piperazine (Ppz). Five complexes are mixed-imine-ligand with anionic-fluorinated pyrazolate [3,5-(CF
    Sprache Englisch
    Erscheinungsdatum 2018-08-06
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 1484438-2
    ISSN 1520-510X ; 0020-1669
    ISSN (online) 1520-510X
    ISSN 0020-1669
    DOI 10.1021/acs.inorgchem.8b01131
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Primary Ciliary Dyskinesia as a Cause of Repeating Atelectasis in the Neonatal Period.

    Primo, Arlete Esteves Lopes / Brock Zacharias, Romy Schmidt / de Moraes, Amanda Dias / da Silva Filho, Luiz Vicente Ribeiro Ferreira / Trujillo, Daniela Rodriguez / Yoshida, Renata de Araújo Monteiro / Warth, Arno Noberto / Rebello, Celso Moura

    The American journal of case reports

    2020  Band 21, Seite(n) e921949

    Abstract: BACKGROUND Primary ciliary dyskinesia (PCD) is a disease characterized by motor ciliary dysfunction, which leads to the accumulation of secretions in the lower airways and, consequently, to atelectasis and repeated infections. During the neonatal period, ...

    Abstract BACKGROUND Primary ciliary dyskinesia (PCD) is a disease characterized by motor ciliary dysfunction, which leads to the accumulation of secretions in the lower airways and, consequently, to atelectasis and repeated infections. During the neonatal period, diagnosis can be difficult because the symptoms are frequently associated with other respiratory diseases common in neonates. The laterality defects should warn the clinician of the need for further investigation using clinical criteria, but the confirmation depends on a genetic test. CASE REPORT The objective of this report is to present a case of PCD manifesting in the neonatal period that was diagnosed due to respiratory failure associated with recurrent atelectasis and situs inversus totalis. CONCLUSIONS This disease is not well known by neonatologists, but early diagnosis decreases morbidity and improves patient quality of life.
    Mesh-Begriff(e) Administration, Inhalation ; Ciliary Motility Disorders/complications ; Ciliary Motility Disorders/therapy ; Continuous Positive Airway Pressure ; Diagnosis, Differential ; Humans ; Infant, Newborn ; Male ; Pulmonary Atelectasis/etiology ; Pulmonary Atelectasis/therapy ; Respiratory Distress Syndrome, Newborn/etiology ; Respiratory Distress Syndrome, Newborn/therapy ; Situs Inversus
    Sprache Englisch
    Erscheinungsdatum 2020-06-11
    Erscheinungsland United States
    Dokumenttyp Case Reports ; Journal Article
    ZDB-ID 2517183-5
    ISSN 1941-5923 ; 1941-5923
    ISSN (online) 1941-5923
    ISSN 1941-5923
    DOI 10.12659/AJCR.921949
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Strengthening self-regulation and reducing poverty to prevent adolescent depression and anxiety: Rationale, approach and methods of the ALIVE interdisciplinary research collaboration in Colombia, Nepal and South Africa.

    Lund, Crick / Jordans, Mark J D / Garman, Emily / Araya, Ricardo / Avendano, Mauricio / Bauer, Annette / Bahure, Vikram / Dua, Tarun / Eleftheriou, Georgia / Evans-Lacko, Sara / García Rodríguez, Juan Felipe / Gautam, Kamal / Gevonden, Martin / Hessel, Philipp / Kohrt, Brandon A / Krabbendam, Lydia / Luitel, Nagendra P / Roy, Sanchari / Seifert Bonifaz, Manuel /
    Singh, Rakesh / Sinichi, Mohammadamin / Sorsdahl, Katherine / Thornicroft, Graham / Tol, Wietse A / Trujillo, Daniela / van der Merwe, Nicci / Wahid, Syed Shabab / Yarrow, Paula

    Epidemiology and psychiatric sciences

    2023  Band 32, Seite(n) e69

    Abstract: Aims: Depression and anxiety are the leading contributors to the global burden of disease among young people, accounting for over a third (34.8%) of years lived with disability. Yet there is limited evidence for interventions that prevent adolescent ... ...

    Abstract Aims: Depression and anxiety are the leading contributors to the global burden of disease among young people, accounting for over a third (34.8%) of years lived with disability. Yet there is limited evidence for interventions that prevent adolescent depression and anxiety in low- and middle-income countries (LMICs), where 90% of adolescents live. This article introduces the 'Improving Adolescent mentaL health by reducing the Impact of poVErty (ALIVE)' study, its conceptual framework, objectives, methods and expected outcomes. The aim of the ALIVE study is to develop and pilot-test an intervention that combines poverty reduction with strengthening self-regulation to prevent depression and anxiety among adolescents living in urban poverty in Colombia, Nepal and South Africa.
    Methods: This aim will be achieved by addressing four objectives: (1) develop a conceptual framework that identifies the causal mechanisms linking poverty, self-regulation and depression and anxiety; (2) develop a multi-component selective prevention intervention targeting self-regulation and poverty among adolescents at high risk of developing depression or anxiety; (3) adapt and validate instruments to measure incidence of depression and anxiety, mediators and implementation parameters of the prevention intervention; and (4) undertake a four-arm pilot cluster randomised controlled trial to assess the feasibility, acceptability and cost of the selective prevention intervention in the three study sites.
    Results: The contributions of this study include the active engagement and participation of adolescents in the research process; a focus on the causal mechanisms of the intervention; building an evidence base for prevention interventions in LMICs; and the use of an interdisciplinary approach.
    Conclusions: By developing and evaluating an intervention that addresses multidimensional poverty and self-regulation, ALIVE can make contributions to evidence on the integration of mental health into broader development policy and practice.
    Mesh-Begriff(e) Adolescent ; Humans ; Anxiety/prevention & control ; Anxiety/psychology ; Colombia/epidemiology ; Depression/psychology ; Interdisciplinary Research ; Nepal ; Poverty ; Self-Control ; South Africa/epidemiology
    Sprache Englisch
    Erscheinungsdatum 2023-12-13
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2607964-1
    ISSN 2045-7979 ; 2045-7960
    ISSN (online) 2045-7979
    ISSN 2045-7960
    DOI 10.1017/S2045796023000811
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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