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  1. Artikel ; Online: Bioactive agents from Parkia biglobosa (Jacq.) R.Br. ex G. Don bark extracts for health promotion and nutraceutical uses.

    Sut, Stefania / Dall'Acqua, Stefano / Sinan, Kouadio Ibrahime / Zengin, Gokhan / Uba, Abdullah Ibrahim / Etienne, Ouattara Katinan / Jugreet, Sharmeen / Mahomoodally, Mohamad Fawzi

    Journal of the science of food and agriculture

    2024  Band 104, Heft 5, Seite(n) 2820–2831

    Abstract: Background: Parkia biglobosa stem bark extracts were prepared using methanol, methanol 80%, water and ethyl acetate to investigate their phytochemical contents, as well as antioxidant and enzyme inhibitory properties.: Results: Liquid chromatography ( ...

    Abstract Background: Parkia biglobosa stem bark extracts were prepared using methanol, methanol 80%, water and ethyl acetate to investigate their phytochemical contents, as well as antioxidant and enzyme inhibitory properties.
    Results: Liquid chromatography (LC) quadrupole time-of-flight mass spectrometry (MS) and LC-MS
    Conclusion: The present study demonstrated that the stem bark extracts of P. biglobosa contains good amount of phytochemical and extracts present significant antioxidant, as well as reasonable enzyme inhibitory effects. Hence, these findings suggest that further studies can be performed on more specific biological targets and models of bioactivity to determine their safe usage as a nutraceutical or for the preparation functional foods. © 2023 The Authors. Journal of The Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
    Mesh-Begriff(e) Antioxidants/chemistry ; Plant Extracts/chemistry ; Butyrylcholinesterase ; Methanol/analysis ; Acetylcholinesterase ; Plant Bark/chemistry ; Phenols/chemistry ; Flavonoids/analysis ; Phytochemicals/pharmacology ; Phytochemicals/analysis ; Rutin/analysis ; Dietary Supplements/analysis ; Water/analysis ; Health Promotion ; Acetates
    Chemische Substanzen Antioxidants ; ethyl acetate (76845O8NMZ) ; Plant Extracts ; Butyrylcholinesterase (EC 3.1.1.8) ; Methanol (Y4S76JWI15) ; Acetylcholinesterase (EC 3.1.1.7) ; Phenols ; Flavonoids ; Phytochemicals ; Rutin (5G06TVY3R7) ; Water (059QF0KO0R) ; Acetates
    Sprache Englisch
    Erscheinungsdatum 2024-01-05
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 184116-6
    ISSN 1097-0010 ; 0022-5142
    ISSN (online) 1097-0010
    ISSN 0022-5142
    DOI 10.1002/jsfa.13170
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Essential Oils Composition and Biological Activity of

    Eltayeb, Loai M H / Yagi, Sakina / Mohamed, Hanan M M / Zengin, Gokhan / Shariati, Mohammad Ali / Rebezov, Maksim / Uba, Abdullah Ibrahim / Lorenzo, Jose Manuel

    Molecules (Basel, Switzerland)

    2023  Band 28, Heft 3

    Abstract: Generally, there are scant data about the constituents and eventually the biological activity of essential oils (EOs) from aromatic plants that grow naturally in Sudan. The present study aimed to determine the chemical composition, and antioxidant and ... ...

    Abstract Generally, there are scant data about the constituents and eventually the biological activity of essential oils (EOs) from aromatic plants that grow naturally in Sudan. The present study aimed to determine the chemical composition, and antioxidant and enzyme inhibitory activities of EO extracted from the fruit of
    Mesh-Begriff(e) Oils, Volatile/pharmacology ; Oils, Volatile/chemistry ; Lavandula/chemistry ; Chamaecyparis/chemistry ; Chrysopogon ; Sudan ; Butyrylcholinesterase ; Monoterpenes ; Antioxidants/pharmacology ; Antioxidants/chemistry ; Sesquiterpenes/pharmacology
    Chemische Substanzen Oils, Volatile ; Butyrylcholinesterase (EC 3.1.1.8) ; Monoterpenes ; Antioxidants ; Sesquiterpenes
    Sprache Englisch
    Erscheinungsdatum 2023-01-19
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28031005
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Synthesis, molecular modeling, in vivo study and anticancer activity against prostate cancer of (+) (S)-naproxen derivatives.

    Birgül, Kaan / Yıldırım, Yeliz / Karasulu, H Yeşim / Karasulu, Ercüment / Uba, Abdullah Ibrahim / Yelekçi, Kemal / Bekçi, Hatice / Cumaoğlu, Ahmet / Kabasakal, Levent / Yılmaz, Özgür / Küçükgüzel, Ş Güniz

    European journal of medicinal chemistry

    2020  Band 208, Seite(n) 112841

    Abstract: In this study, (S)-naproxen thiosemicarbazides (3a-d), 1,2,4-triazoles (4a-c), triazole-thioether hybride compounds (5a-p) were synthesized and their structures (3a, 3d, 4a and 5a-p) were confirmed by FT-IR, ...

    Abstract In this study, (S)-naproxen thiosemicarbazides (3a-d), 1,2,4-triazoles (4a-c), triazole-thioether hybride compounds (5a-p) were synthesized and their structures (3a, 3d, 4a and 5a-p) were confirmed by FT-IR,
    Mesh-Begriff(e) Animals ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/metabolism ; Antineoplastic Agents/therapeutic use ; Apoptosis/drug effects ; Cell Line, Tumor ; Drug Screening Assays, Antitumor ; Enzyme Inhibitors/chemical synthesis ; Enzyme Inhibitors/metabolism ; Enzyme Inhibitors/therapeutic use ; Humans ; Male ; Methionyl Aminopeptidases/antagonists & inhibitors ; Methionyl Aminopeptidases/metabolism ; Mice, Nude ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Molecular Structure ; Naproxen/analogs & derivatives ; Naproxen/metabolism ; Naproxen/therapeutic use ; Prostatic Neoplasms/drug therapy ; Protein Binding ; Stereoisomerism ; Structure-Activity Relationship
    Chemische Substanzen Antineoplastic Agents ; Enzyme Inhibitors ; Naproxen (57Y76R9ATQ) ; METAP2 protein, human (EC 3.4.11.18) ; Metap2 protein, mouse (EC 3.4.11.18) ; Methionyl Aminopeptidases (EC 3.4.11.18)
    Sprache Englisch
    Erscheinungsdatum 2020-09-16
    Erscheinungsland France
    Dokumenttyp Journal Article
    ZDB-ID 188597-2
    ISSN 1768-3254 ; 0009-4374 ; 0223-5234
    ISSN (online) 1768-3254
    ISSN 0009-4374 ; 0223-5234
    DOI 10.1016/j.ejmech.2020.112841
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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