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  1. Article ; Online: Determinants of Undernutrition among Children Admitted to a Pediatric Hospital in Port Sudan, Sudan.

    Chiopris, Giulia / Chiopris, Caterina / Valenti, Manuela / Esposito, Susanna

    Nutrients

    2024  Volume 16, Issue 6

    Abstract: Severe acute undernutrition (SAU) is still a crucial global health issue in the 0-59 months population, increasing the risk of mortality as well as of long-term consequences. In Sudan, 3.3 million children suffered from acute malnutrition between 2018 ... ...

    Abstract Severe acute undernutrition (SAU) is still a crucial global health issue in the 0-59 months population, increasing the risk of mortality as well as of long-term consequences. In Sudan, 3.3 million children suffered from acute malnutrition between 2018 and 2019. This study was planned to evaluate, in the area of Port Sudan, the prevalence of acute undernutrition after the COVID-19 pandemic and to identify the most important factors favoring the development of acute undernutrition. The available clinical records of all the under-five children (
    MeSH term(s) Child ; Infant ; Female ; Humans ; Kwashiorkor ; Hospitals, Pediatric ; Pandemics ; Malnutrition/epidemiology ; Protein-Energy Malnutrition/epidemiology ; Cachexia/epidemiology ; Hospitalization ; Prevalence ; Growth Disorders/epidemiology
    Language English
    Publishing date 2024-03-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu16060787
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Suspected Severe Malaria in a Sudanese Patient Affected by Sickle Cell Disease Who Was Treated with Hydroxyurea

    Chiopris, Giulia / Maccario, Stefano / Eisa Artaiga, Tawaddud Hassan / Ibrahim Mohamed, Abdalrhman / Valenti, Manuela / Esposito, Susanna

    Pathogens. 2021 Aug. 04, v. 10, no. 8

    2021  

    Abstract: Sickle cell disease (SCD) is the most common genetic disease in sub-Saharan Africa. The signs and symptoms of SCD usually begin in early childhood. Characteristic features of this disorder include anaemia, repeated infections, and periodic episodes of ... ...

    Abstract Sickle cell disease (SCD) is the most common genetic disease in sub-Saharan Africa. The signs and symptoms of SCD usually begin in early childhood. Characteristic features of this disorder include anaemia, repeated infections, and periodic episodes of pain. Malaria is one of the infections that can occur in patients with SCD in endemic countries. Many guidelines recommend antimalarial chemoprophylaxis in these patients, although the debate on which drug should be used is still ongoing. Hydroxyurea (HU), which is considered a safe and effective treatment for both children and adults with SCD, seems to affect the incidence and severity of malaria, although these impacts have yet to be fully demonstrated. We report a case of an eight-and-a-half-year-old Sudanese boy with SCD treated with HU admitted for suspected severe malaria who showed a recrudescence after first-line treatment. Although he had undergone splenectomy and thus belonged to a category of patients at high risk for infectious complications, he was not receiving any malaria chemoprophylaxis. This case emphasises the importance of the routine administration of malaria prophylaxis to children with SCD living in endemic areas, even when they are treated with HU, and especially if they are at high risk for infectious complications because they have undergone splenectomy. There is an urgent need for further research to evaluate the most appropriate regimen and its optimal duration.
    Keywords antimalarials ; boys ; chemoprevention ; childhood ; disease prevention ; hydroxyurea ; malaria ; pain ; patients ; risk ; sickle cell anemia ; Sub-Saharan Africa
    Language English
    Dates of publication 2021-0804
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens10080985
    Database NAL-Catalogue (AGRICOLA)

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  3. Article: Amoebic Dysentery Complicated by Hypovolemic Shock and Sepsis in an Infant with Severe Acute Malnutrition: A Case Report.

    Dal Canto, Giulia / Artaiga, Tawaddud Hassan Eisa / Mohamed, Abdulrahman Ibrahiem / Hassan, Hayat Amin Makki / Adam, Doaa Mahmoud / Ahmed, Moram Awadalla Ibrahiem / Motwali, Jihad / Valenti, Manuela / Esposito, Susanna

    Microorganisms

    2023  Volume 11, Issue 1

    Abstract: Diarrheal disease continues to be a leading cause of death in children under five years old in developing countries, where it is responsible for the death of approximately half a million children each year. Establishing the cause of diarrheal disease can ...

    Abstract Diarrheal disease continues to be a leading cause of death in children under five years old in developing countries, where it is responsible for the death of approximately half a million children each year. Establishing the cause of diarrheal disease can be difficult in developing areas due to the lack of diagnostic tests, and thus empirical therapies are often required. In these settings, the choice of antibiotic (or the choice to not give it) depends on suspected agents, host conditions and local epidemiology. Herein, we report a representative case of a ten-month-old male patient with severe acute malnutrition (SAM) admitted to the Emergency Paediatric Clinic in Port Sudan for amoebic dysentery complicated by hypovolemic shock and sepsis, treated by target therapy for
    Language English
    Publishing date 2023-01-08
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms11010165
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Suspected Severe Malaria in a Sudanese Patient Affected by Sickle Cell Disease Who Was Treated with Hydroxyurea.

    Chiopris, Giulia / Maccario, Stefano / Eisa Artaiga, Tawaddud Hassan / Ibrahim Mohamed, Abdalrhman / Valenti, Manuela / Esposito, Susanna

    Pathogens (Basel, Switzerland)

    2021  Volume 10, Issue 8

    Abstract: Sickle cell disease (SCD) is the most common genetic disease in sub-Saharan Africa. The signs and symptoms of SCD usually begin in early childhood. Characteristic features of this disorder include anaemia, repeated infections, and periodic episodes of ... ...

    Abstract Sickle cell disease (SCD) is the most common genetic disease in sub-Saharan Africa. The signs and symptoms of SCD usually begin in early childhood. Characteristic features of this disorder include anaemia, repeated infections, and periodic episodes of pain. Malaria is one of the infections that can occur in patients with SCD in endemic countries. Many guidelines recommend antimalarial chemoprophylaxis in these patients, although the debate on which drug should be used is still ongoing. Hydroxyurea (HU), which is considered a safe and effective treatment for both children and adults with SCD, seems to affect the incidence and severity of malaria, although these impacts have yet to be fully demonstrated. We report a case of an eight-and-a-half-year-old Sudanese boy with SCD treated with HU admitted for suspected severe malaria who showed a recrudescence after first-line treatment. Although he had undergone splenectomy and thus belonged to a category of patients at high risk for infectious complications, he was not receiving any malaria chemoprophylaxis. This case emphasises the importance of the routine administration of malaria prophylaxis to children with SCD living in endemic areas, even when they are treated with HU, and especially if they are at high risk for infectious complications because they have undergone splenectomy. There is an urgent need for further research to evaluate the most appropriate regimen and its optimal duration.
    Language English
    Publishing date 2021-08-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens10080985
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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