Artikel ; Online: Idiopathic granulomatous mastitis: experience at a New York hospital.
Annals of the Royal College of Surgeons of England
2021 Band 104, Heft 7, Seite(n) 543–547
Abstract: Introduction: Idiopathic granulomatous mastitis (IGM) often mimics breast cancer. Presentation includes pain, palpable mass, suppuration or suspicious imaging. Widely reported in Asia and the Middle East, IGM is diagnosed after excluding specific ... ...
Abstract | Introduction: Idiopathic granulomatous mastitis (IGM) often mimics breast cancer. Presentation includes pain, palpable mass, suppuration or suspicious imaging. Widely reported in Asia and the Middle East, IGM is diagnosed after excluding specific granulomatous mastitis (SGM). Aetiology remains unknown. Lactation, prolactinaemia, ethnicity, autoimmune disease and Corynebacteria are associated. Treatment is controversial and the prevalence rising. Surgery and non-operative treatments including antibiotics, non-steroidal anti-inflammatory drugs (NSAIDs), steroids, methotrexate and observation have advocates. Methods: A retrospective chart review of 63 patients with IGM from 2008 to 2018 was undertaken focusing on birthplace, age, clinical presentation, wound cultures, imaging, treatments and outcomes. Results: Sixty-one of 63 patients were Hispanic; 53 were Mexican-born women aged 23-46. Clinical presentation included pain, painful mass, painless mass, suppuration and abnormal imaging. Some 31/61 ultrasound examinations and 17/33 mammograms were deemed Breast Imaging Reporting and Data System (BI-RADS) score 4 or 5. Management included antibiotics (43), incision and drainage (24), NSAIDs (29), steroids (8), lumpectomy (18) and observation (12). Some 12/20 patients with painless masses resolved with observation, 3 received NSAIDs, 2 received steroids and 3 underwent lumpectomies. Antibiotics resolved 8/43 cases, 5 needed incision and drainage, 26 received NSAIDs, 6 received steroids and 5 underwent lumpectomies. Nineteen patients had indolent disease or recurrence. Conclusions: Excluding malignancy is critical, treatment challenging and recurrence common in IGM. A preponderance of patients were Mexican-born, similar to other reports from the USA. Over 50% of IGM cases had suspicious BI-RADS scores. Best management remains a challenge and ranges from observation to lumpectomy. |
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Mesh-Begriff(e) | Anti-Bacterial Agents/therapeutic use ; Anti-Inflammatory Agents, Non-Steroidal/therapeutic use ; Breast Neoplasms/diagnosis ; Female ; Granulomatous Mastitis/diagnosis ; Granulomatous Mastitis/epidemiology ; Granulomatous Mastitis/therapy ; Hospitals ; Humans ; Immunoglobulin M/therapeutic use ; New York ; Pain ; Retrospective Studies ; Steroids/therapeutic use ; Suppuration/drug therapy |
Chemische Substanzen | Anti-Bacterial Agents ; Anti-Inflammatory Agents, Non-Steroidal ; Immunoglobulin M ; Steroids |
Sprache | Englisch |
Erscheinungsdatum | 2021-11-23 |
Erscheinungsland | England |
Dokumenttyp | Journal Article |
ZDB-ID | 80044-2 |
ISSN | 1478-7083 ; 0035-8843 |
ISSN (online) | 1478-7083 |
ISSN | 0035-8843 |
DOI | 10.1308/rcsann.2021.0239 |
Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
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