Article ; Online: Intestinal IFN-γ-producing type 1 regulatory T cells coexpress CCR5 and programmed cell death protein 1 and downregulate IL-10 in the inflamed guts of patients with inflammatory bowel disease.
The Journal of allergy and clinical immunology
2018 Volume 142, Issue 5, Page(s) 1537–1547.e8
Abstract: Background: IL-10 is an anti-inflammatory cytokine required for intestinal immune homeostasis. It mediates suppression of T-cell responses by type 1 regulatory T (T: Objective: We aimed to identify and characterize human intestinal T: Methods: CD4! ...
| Abstract | Background: IL-10 is an anti-inflammatory cytokine required for intestinal immune homeostasis. It mediates suppression of T-cell responses by type 1 regulatory T (T Objective: We aimed to identify and characterize human intestinal T Methods: CD4 Results: Intestinal T Conclusions: We provide the first ex vivo characterization of human intestinal T |
|||||
|---|---|---|---|---|---|---|
| MeSH term(s) | Adult ; Aged ; Animals ; Cells, Cultured ; Colonic Neoplasms/immunology ; Cytokines/immunology ; Female ; Humans ; Inflammatory Bowel Diseases/immunology ; Intestinal Mucosa/immunology ; Male ; Mice, Inbred C57BL ; Mice, Transgenic ; Middle Aged ; Programmed Cell Death 1 Receptor/immunology ; Receptors, CCR5/immunology ; T-Lymphocytes, Regulatory/immunology ; Young Adult | |||||
| Chemical Substances | CCR5 protein, human ; Cytokines ; PDCD1 protein, human ; Programmed Cell Death 1 Receptor ; Receptors, CCR5 | |||||
| Language | English | |||||
| Publishing date | 2018-01-31 | |||||
| Publishing country | United States | |||||
| Document type | Journal Article ; Research Support, Non-U.S. Gov't | |||||
| ZDB-ID | 121011-7 | |||||
| ISSN | 1097-6825 ; 1085-8725 ; 0091-6749 | |||||
| ISSN (online) | 1097-6825 ; 1085-8725 | |||||
| ISSN | 0091-6749 | |||||
| DOI | 10.1016/j.jaci.2017.12.984 | |||||
| Shelf mark |
|
|||||
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
Full text online
More links
Kategorien
In stock of ZB MED Cologne/Königswinter
| Uh III Zs.92: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.