Artikel ; Online: The brain is the conductor: diet-induced inflammation overlapping physiological control of body mass and metabolism.
Arquivos brasileiros de endocrinologia e metabologia
2009 Band 53, Heft 2, Seite(n) 151–158
Abstract: Obesity is currently a worldwide pandemic. It affects more than 300 million humans and it will probably increase over the next 20 years. The consumption of calorie-rich foods is responsible for most of the obesity cases, but not all humans exposed to ... ...
Abstract | Obesity is currently a worldwide pandemic. It affects more than 300 million humans and it will probably increase over the next 20 years. The consumption of calorie-rich foods is responsible for most of the obesity cases, but not all humans exposed to high-calorie diets develop the disease. This fact has prompted researchers to investigate the mechanisms linking the consumption of high-calorie diets to the generation of an imbalance between energy intake and expenditure. According to recent studies, the exposure to fat-rich diets induces an inflammatory response in the hypothalamic areas involved in the control of feeding and thermogenesis. The inflammatory process damages the neuronal circuitries that maintain the homeostatic control of the body's energy stores, therefore favoring body mass gain. This review will focus on the main advances obtained in this field. |
---|---|
Mesh-Begriff(e) | Animals ; Body Composition ; Body Mass Index ; Diet ; Dietary Fats/adverse effects ; Dietary Fats/metabolism ; Eating/physiology ; Energy Intake/physiology ; Energy Metabolism/physiology ; Humans ; Hypothalamic Diseases/etiology ; Hypothalamic Diseases/physiopathology ; Hypothalamus/physiology ; Leptin/physiology ; Limbic Encephalitis/etiology ; Limbic Encephalitis/physiopathology ; Obesity/etiology ; Obesity/metabolism ; Thermogenesis/physiology |
Chemische Substanzen | Dietary Fats ; Leptin |
Sprache | Englisch |
Erscheinungsdatum | 2009-04-15 |
Erscheinungsland | Brazil |
Dokumenttyp | Journal Article ; Research Support, Non-U.S. Gov't ; Review |
ZDB-ID | 603919-4 |
ISSN | 1677-9487 ; 0004-2730 |
ISSN (online) | 1677-9487 |
ISSN | 0004-2730 |
DOI | 10.1590/s0004-27302009000200006 |
Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
Zusatzmaterialien
Kategorien
Verfügbar in ZB MED Köln/Königswinter
Zs.B 264: Hefte anzeigen | Standort: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
Über subito bestellen
Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.