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  1. Artikel: Petites molécules dans la polyarthrite rhumatoïde.

    Verdon, Aurore / Lauper, Kim

    Revue medicale suisse

    2020  Band 16, Heft 685, Seite(n) 477–480

    Abstract: If treatment target is not reached with a conventional disease-modifying antirheumatic drug (csDMARD) such as methotrexate in rheumatoid arthritis, it is recommended to use a biologic (bDMARD) or a Janus kinase (JAK) inhibitor, small synthetic molecules ... ...

    Titelübersetzung Small molecules treatment in rheumatoid arthritis.
    Abstract If treatment target is not reached with a conventional disease-modifying antirheumatic drug (csDMARD) such as methotrexate in rheumatoid arthritis, it is recommended to use a biologic (bDMARD) or a Janus kinase (JAK) inhibitor, small synthetic molecules recently developed. Oral administration and short half-life can favour the choice of JAK inhibitors, as well as the opportunity to use it in monotherapy, even though co-treatment with csDMARD is recommended. As yet long-term studies are lacking, little is known about adverse effects although risk of herpes virus infections is clearly higher with JAK inhibitors than bDMARD treatments.
    Mesh-Begriff(e) Antirheumatic Agents/administration & dosage ; Antirheumatic Agents/adverse effects ; Antirheumatic Agents/chemistry ; Antirheumatic Agents/therapeutic use ; Arthritis, Rheumatoid/drug therapy ; Drug Therapy, Combination ; Humans ; Janus Kinase Inhibitors/administration & dosage ; Janus Kinase Inhibitors/adverse effects ; Janus Kinase Inhibitors/chemistry ; Janus Kinase Inhibitors/therapeutic use ; Methotrexate/therapeutic use ; Treatment Outcome
    Chemische Substanzen Antirheumatic Agents ; Janus Kinase Inhibitors ; Methotrexate (YL5FZ2Y5U1)
    Sprache Französisch
    Erscheinungsdatum 2020-03-17
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2177010-4
    ISSN 1660-9379
    ISSN 1660-9379
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel: Lupus érythémateux systémique et Covid-19.

    Verdon, Aurore / Zanisi, Laura / Melong Pianta, Cathy / Iudici, Michele

    Revue medicale suisse

    2021  Band 17, Heft 729, Seite(n) 487–490

    Abstract: This article synthesizes the main aspects of the management of systemic lupus erythematosus patients in the context of the COVID-19 pandemic based on published literature. We will therefore develop on topics such as the risk of getting infected, the ... ...

    Titelübersetzung Systemic Lupus Erythematosus and COVID-19.
    Abstract This article synthesizes the main aspects of the management of systemic lupus erythematosus patients in the context of the COVID-19 pandemic based on published literature. We will therefore develop on topics such as the risk of getting infected, the differences in COVID-19 clinical course and severity compared to general population, the role of antiphospholipid antibodies in thrombotic complications, and treatment strategies.
    Mesh-Begriff(e) Antiphospholipid Syndrome/diagnosis ; Antiphospholipid Syndrome/therapy ; COVID-19 ; Humans ; Lupus Erythematosus, Systemic ; Pandemics ; SARS-CoV-2
    Sprache Französisch
    Erscheinungsdatum 2021-03-10
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2177010-4
    ISSN 1660-9379
    ISSN 1660-9379
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

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