Artikel: Calcium-sensing receptor-mediated NLRP3 inflammasome activation in rheumatoid arthritis and autoinflammation.
2023 Band 13, Seite(n) 1078569
Abstract: The calcium-sensing receptor (CaSR) is expressed in many cell types - including immune cells and in particular circulating monocytes. Here, the receptor plays an important physiological role as a regulator of constitutive macropinocytosis. This review ... ...
Abstract | The calcium-sensing receptor (CaSR) is expressed in many cell types - including immune cells and in particular circulating monocytes. Here, the receptor plays an important physiological role as a regulator of constitutive macropinocytosis. This review article provides an overview of the literature on the role of the calcium sensing receptor in the context of inflammatory processes. Special emphasis is laid upon the importance for monocytes in the context of rheumatoid arthritis. We have shown previously, that stimulation of the receptor by increased extracellular Ca |
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Sprache | Englisch |
Erscheinungsdatum | 2023-01-06 |
Erscheinungsland | Switzerland |
Dokumenttyp | Journal Article ; Review |
ZDB-ID | 2564217-0 |
ISSN | 1664-042X |
ISSN | 1664-042X |
DOI | 10.3389/fphys.2022.1078569 |
Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
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