Artikel ; Online: A review on Zika vaccine development.
Pathogens and disease
2024 Band 82
Abstract: Zika virus (ZIKV), which belongs to the Flavivirus family, is mainly transmitted via the bite of Aedes mosquitoes. In newborns, ZIKV infection can cause severe symptoms such as microcephaly, while in adults, it can lead to Guillain‒Barré syndrome (GBS). ... ...
Abstract | Zika virus (ZIKV), which belongs to the Flavivirus family, is mainly transmitted via the bite of Aedes mosquitoes. In newborns, ZIKV infection can cause severe symptoms such as microcephaly, while in adults, it can lead to Guillain‒Barré syndrome (GBS). Due to the lack of specific therapeutic methods against ZIKV, the development of a safe and effective vaccine is extremely important. Several potential ZIKV vaccines, such as live attenuated, inactivated, nucleic acid, viral vector, and recombinant subunit vaccines, have demonstrated promising outcomes in clinical trials involving human participants. Therefore, in this review, the recent developmental progress, advantages and disadvantages of these five vaccine types are examined, and practical recommendations for future development are provided. |
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Mesh-Begriff(e) | Infant, Newborn ; Animals ; Adult ; Humans ; Zika Virus ; Zika Virus Infection/prevention & control ; Mosquito Vectors ; Vaccines |
Chemische Substanzen | Vaccines |
Sprache | Englisch |
Erscheinungsdatum | 2024-01-09 |
Erscheinungsland | United States |
Dokumenttyp | Review ; Journal Article |
ISSN | 2049-632X |
ISSN (online) | 2049-632X |
DOI | 10.1093/femspd/ftad036 |
Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
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