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  1. Artikel ; Online: Changes in physical activity, sedentary behaviour and sleep following pulmonary rehabilitation: a systematic review and network meta-analysis.

    Manifield, James / Chaudhry, Yousuf / Singh, Sally J / Ward, Thomas J C / Whelan, Maxine E / Orme, Mark W

    European respiratory review : an official journal of the European Respiratory Society

    2024  Band 33, Heft 172

    Abstract: Background: The variety of innovations to traditional centre-based pulmonary rehabilitation (CBPR), including different modes of delivery and adjuncts, are likely to lead to differential responses in physical activity, sedentary behaviour and sleep.: ... ...

    Abstract Background: The variety of innovations to traditional centre-based pulmonary rehabilitation (CBPR), including different modes of delivery and adjuncts, are likely to lead to differential responses in physical activity, sedentary behaviour and sleep.
    Objectives: To examine the relative effectiveness of different pulmonary rehabilitation-based interventions on physical activity, sedentary behaviour and sleep.
    Methods: Randomised trials in chronic respiratory disease involving pulmonary rehabilitation-based interventions were systematically searched for. Network meta-analyses compared interventions for changes in physical activity, sedentary behaviour and sleep in COPD.
    Results: 46 studies were included, and analyses were performed on most common outcomes: steps per day (k=24), time spent in moderate-to-vigorous physical activity (MVPA; k=12) and sedentary time (k=8). There were insufficient data on sleep outcomes (k=3). CBPR resulted in greater steps per day and MVPA and reduced sedentary time compared to usual care. CBPR+physical activity promotion resulted in greater increases in steps per day compared to both usual care and CBPR, with greater increases in MVPA and reductions in sedentary time compared to usual care, but not CBPR. Home-based pulmonary rehabilitation resulted in greater increases in steps per day and decreases in sedentary time compared to usual care. Compared to usual care, CBPR+physical activity promotion was the only intervention where the lower 95% confidence interval for steps per day surpassed the minimal important difference. No pulmonary rehabilitation-related intervention resulted in greater increases in MVPA or reductions in sedentary time compared to CBPR.
    Conclusion: The addition of physical activity promotion to pulmonary rehabilitation improves volume of physical activity, but not intensity, compared to CBPR. High risk of bias and low certainty of evidence suggests that these results should be viewed with caution.
    Mesh-Begriff(e) Humans ; Sedentary Behavior ; Network Meta-Analysis ; Exercise ; Sleep
    Sprache Englisch
    Erscheinungsdatum 2024-04-10
    Erscheinungsland England
    Dokumenttyp Meta-Analysis ; Systematic Review ; Journal Article ; Review
    ZDB-ID 1077620-5
    ISSN 1600-0617 ; 0905-9180
    ISSN (online) 1600-0617
    ISSN 0905-9180
    DOI 10.1183/16000617.0225-2023
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel: The impact of the meta-analysis of pulmonary rehabilitation by Lacasse and colleagues: transforming pulmonary rehabilitation from "art to science".

    Gephine, Sarah / Simonelli, Carla / Vagheggini, Guido / Evans, Rachael / Ward, Thomas J C

    Breathe (Sheffield, England)

    2022  Band 18, Heft 2, Seite(n) 220021

    Abstract: Pulmonaryrehab was transformed in the 1990s into the standard of care for COPD: this article focuses on the impact of the 1996 meta-analysis by Lacasse and colleagues which provided the evidence to silence the ... ...

    Abstract #Pulmonaryrehab was transformed in the 1990s into the standard of care for COPD: this article focuses on the impact of the 1996 meta-analysis by Lacasse and colleagues which provided the evidence to silence the sceptics
    Sprache Englisch
    Erscheinungsdatum 2022-06-07
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2562899-9
    ISSN 2073-4735 ; 1810-6838
    ISSN (online) 2073-4735
    ISSN 1810-6838
    DOI 10.1183/20734735.0021-2022
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Change in V˙O

    Ward, Thomas J C / Plumptre, Charles D / Dolmage, Thomas E / Jones, Amy V / Trethewey, Ruth / Divall, Pip / Singh, Sally J / Lindley, Martin R / Steiner, Michael C / Evans, Rachael A

    Chest

    2020  Band 158, Heft 1, Seite(n) 131–144

    Abstract: Background: Despite the wide-ranging benefits of pulmonary rehabilitation, conflicting results remain regarding whether people with COPD can improve their peak oxygen uptake (V˙O: Research question: The goal of this study was to investigate the ... ...

    Abstract Background: Despite the wide-ranging benefits of pulmonary rehabilitation, conflicting results remain regarding whether people with COPD can improve their peak oxygen uptake (V˙O
    Research question: The goal of this study was to investigate the effect of aerobic training and exercise prescription on V˙O
    Study design and methods: A systematic review was performed by using MEDLINE, Embase, Cumulative Index to Nursing and Allied Health Literature, and Cochrane databases for all studies measuring V˙O
    Results: A total of 112 studies were included (participants, N = 3,484): 21 controlled trials (n = 489), of which 13 were randomized (n = 288) and 91 were uncontrolled (n = 2,995) studies. Meta-analysis found a moderate positive change in V˙O
    Interpretation: Overall, people with COPD achieved moderate improvements in V˙O
    Clinical trial registration: PROSPERO; No.: CRD42018099300; URL: https://www.crd.york.ac.uk/prospero/.
    Mesh-Begriff(e) Exercise ; Exercise Therapy ; Humans ; Oxygen Consumption/physiology ; Pulmonary Disease, Chronic Obstructive/physiopathology ; Pulmonary Disease, Chronic Obstructive/rehabilitation
    Sprache Englisch
    Erscheinungsdatum 2020-03-12
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Meta-Analysis ; Research Support, Non-U.S. Gov't ; Systematic Review
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2020.01.053
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Submaximal Eccentric Cycling in People With COPD: Acute Whole-Body Cardiopulmonary and Muscle Metabolic Responses.

    Ward, Thomas J C / Lindley, Martin R / Ferguson, Richard A / Constantin, Despina / Singh, Sally J / Bolton, Charlotte E / Evans, Rachael A / Greenhaff, Paul L / Steiner, Michael C

    Chest

    2020  Band 159, Heft 2, Seite(n) 564–574

    Abstract: Background: Eccentric cycling (ECC) may be an attractive exercise method in COPD because of both low cardiorespiratory demand and perception of effort compared with conventional concentric cycling (CON) at matched mechanical loads. However, it is ... ...

    Abstract Background: Eccentric cycling (ECC) may be an attractive exercise method in COPD because of both low cardiorespiratory demand and perception of effort compared with conventional concentric cycling (CON) at matched mechanical loads. However, it is unknown whether ECC can be performed by individuals with COPD at an intensity able to cause sufficient metabolic stress to improve aerobic capacity.
    Research question: What are the cardiopulmonary and metabolic responses to ECC in people with COPD and healthy volunteers when compared with CON at matched mechanical loads?
    Study design and methods: Thirteen people with COPD (mean ± SD age, 64 ± 9 years; FEV
    Results: At matched mechanical loads, oxygen uptake, minute ventilation, heart rate, systolic BP, respiratory exchange ratio (all P < .001), capillary lactate, perceived breathlessness, and leg fatigue (P < .05) were lower in both groups during ECC than CON. Muscle lactate content increased (P = .008) and muscle phosphocreatine decreased (P = .012) during CON in COPD, which was not evident during ECC.
    Interpretation: Cardiopulmonary and blood lactate responses during submaximal ECC were less compared with during CON at equivalent mechanical workloads in healthy participants and COPD patients, and this was confirmed at a muscle level in COPD patients. Submaximal ECC was well tolerated and allowed greater mechanical work at lower ventilatory cost. However, in people with COPD, a training intervention based on ECC is unlikely to stimulate cardiovascular and metabolic adaptation to the same extent as CON.
    Mesh-Begriff(e) Aged ; Exercise Test/methods ; Exercise Tolerance/physiology ; Female ; Heart Rate/physiology ; Humans ; Male ; Middle Aged ; Muscle, Skeletal/metabolism ; Oxygen Consumption/physiology ; Pulmonary Disease, Chronic Obstructive/metabolism ; Pulmonary Disease, Chronic Obstructive/physiopathology
    Sprache Englisch
    Erscheinungsdatum 2020-09-01
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2020.08.2082
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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