Artikel ; Online: Remdesivir use in the coronavirus disease 2019 pandemic: A mini-review.
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi
2020 Band 54, Heft 1, Seite(n) 27–36
Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative viral pathogen of coronavirus disease 2019 (COVID-19), appears to have various clinical presentations and may result in severe respiratory failure. The global SARS-CoV-2- ... ...
| Abstract | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative viral pathogen of coronavirus disease 2019 (COVID-19), appears to have various clinical presentations and may result in severe respiratory failure. The global SARS-CoV-2-associated viral pneumonia pandemic was first reported in December 2019 in China. Based on known pharmacological mechanisms, many therapeutic drugs have been repurposed to target SARS-CoV-2. Among these drugs, remdesivir appears to be the currently most promising according to several clinical trials and reports of compassionate use. In this mini-review, we summarize the current evidence on the efficacy and challenges of remdesivir for the treatment of coronavirus disease 2019 (COVID-19). |
|---|---|
| Mesh-Begriff(e) | Adenosine Monophosphate/administration & dosage ; Adenosine Monophosphate/analogs & derivatives ; Alanine/administration & dosage ; Alanine/analogs & derivatives ; Antiviral Agents/administration & dosage ; COVID-19/drug therapy ; COVID-19/epidemiology ; China/epidemiology ; Clinical Trials as Topic ; Humans ; Pandemics ; Randomized Controlled Trials as Topic ; SARS-CoV-2/drug effects |
| Chemische Substanzen | Antiviral Agents ; remdesivir (3QKI37EEHE) ; Adenosine Monophosphate (415SHH325A) ; Alanine (OF5P57N2ZX) |
| Schlagwörter | covid19 |
| Sprache | Englisch |
| Erscheinungsdatum | 2020-10-05 |
| Erscheinungsland | England |
| Dokumenttyp | Journal Article ; Review |
| ZDB-ID | 1497590-7 |
| ISSN | 1995-9133 ; 1684-1182 ; 0253-2662 |
| ISSN (online) | 1995-9133 |
| ISSN | 1684-1182 ; 0253-2662 |
| DOI | 10.1016/j.jmii.2020.09.002 |
| Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
Zusatzmaterialien
Kategorien
Verfügbar in ZB MED Köln/Königswinter
| Zs.B 2083: Hefte anzeigen | Standort: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
Über subito bestellen
Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.