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  1. Buch ; Dissertation / Habilitation: Der retinale Venendruck gemessen mit der Kontaktglasdynamometrie und einem neuen Verfahren

    Wetzk, Emilie / Terai, Naim / Siepmann, Timo

    2020  

    Körperschaft Klinik und Poliklinik für Augenheilkunde
    Verfasserangabe von Emilie Wetzk
    Sprache Deutsch
    Umfang IV, 109 Blätter, Illustrationen, Diagramme, 31 cm
    Erscheinungsort Dresden
    Erscheinungsland Deutschland
    Dokumenttyp Buch ; Dissertation / Habilitation
    Dissertation / Habilitation Dissertation, Technische Universität Dresden, 2021
    HBZ-ID HT021707173
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  2. Artikel ; Online: Measurement of the retinal venous pressure with a new instrument in healthy subjects.

    Stodtmeister, Richard / Wetzk, Emilie / Herber, Robert / Pillunat, Karin R / Pillunat, Lutz E

    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

    2021  Band 260, Heft 4, Seite(n) 1237–1244

    Abstract: Background: The retinal venous pressure (RVP) is a determining factor for the blood supply of the retina as well as the optic nerve head and until recently has been measured by contact lens dynamometry (CLD). A new method has been developed, potentially ...

    Abstract Background: The retinal venous pressure (RVP) is a determining factor for the blood supply of the retina as well as the optic nerve head and until recently has been measured by contact lens dynamometry (CLD). A new method has been developed, potentially offering better acceptance. The applicability and the results of both methods were compared.
    Methods: The type of this study is cross sectional. The subjects were 36 healthy volunteers, age 26 ± 5 years (mean ± s). Tonometry: rebound tonometer (RT) (iCare). The measurements were performed during an increase in airway pressure of 20 mmHg (Valsalva manoeuvre). Principle of RVP measurement: the central retinal vein (CRV) is observed during an increase of intraocular pressure (IOP) and at the start of pulsation, which corresponds with the RVP. Two different instruments for the IOP enhancement where used: contact lens dynamometry and the new instrument, IOPstim.
    Principle: a deflated balloon of 8 mm diameter-placed on the sclera laterally of the cornea-is filled with air. As soon as a venous pulsation occurs, filling is stopped and the IOP is measured, equalling the RVP. Examination procedure: randomization of the sequence: CLD or IOPstim, IOP, mydriasis, IOP three single measurements (SM) of the IOP with RT or of the pressure increase with CLD at an airway pressure of 20 mmHg, 5 min break, IOP, and three SM using the second method at equal pressure (20 mmHg).
    Results: Spontaneous pulsation of the CRV was present in all 36 subjects. Pressures are given in mmHg. IOP in mydriasis 15.6 ± 3.3 (m ± s). Median RVP (MRVP)) of the three SM: CLD/IOPstim, 37.7 ± 5.2/24.7 ± 4.8 (t test: p < 0.001). Range of SM: 3.2 ± 1.8/2.9 ± 1.3 (t test: p = 0.36). Intraclass correlation coefficient (ICC) of SM: 0.88/0.83. ANOVA in SM: p = 0.48/0.08. MRVP CLD minus MRVP IOPstim: 13.0 ± 5.6. Ratio MRVP CLD/MRVP IOPstim: 1.56 ± 3.1. Cooperation and agreeability were slightly better with the IOPstim.
    Conclusion: This first study with the IOPstim in humans was deliberately performed in healthy volunteers using Valsalva conditions. As demonstrated by ICC and ANOVA, reproducible SM can be obtained by both methods and the range of the SM does not differ greatly. The higher MRVP in CLD could be explained by the different directions of the force vectors.
    Mesh-Begriff(e) Adult ; Cross-Sectional Studies ; Healthy Volunteers ; Humans ; Intraocular Pressure ; Reproducibility of Results ; Retina ; Tonometry, Ocular/methods ; Venous Pressure/physiology ; Young Adult
    Sprache Englisch
    Erscheinungsdatum 2021-09-09
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 8435-9
    ISSN 1435-702X ; 0721-832X
    ISSN (online) 1435-702X
    ISSN 0721-832X
    DOI 10.1007/s00417-021-05374-y
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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