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  1. AU="Williams, Gareth"
  2. AU="Garber, John J"
  3. AU="Seon-Ah Cha"
  4. AU="Hill, Hanna"
  5. AU=Panteli Michalis
  6. AU="Rocha, Jorge"
  7. AU="Zheng, Yifeng"
  8. AU="Simmons, Benno I."
  9. AU="Rivest, Jean"
  10. AU=Tian Henghe
  11. AU=Rahal Elias A.
  12. AU=Denholt Charlotte
  13. AU=Neale Benjamin M
  14. AU="Simon, Krzysztof"
  15. AU="Srivastava, Abhay Krishna"
  16. AU=Serrano Luis A
  17. AU="D'Orio, Vincent"
  18. AU="Davies, Neville"
  19. AU="Wise, J.C."
  20. AU="Mazer, Benjamin L"
  21. AU="Vellore J. Karthikeyan"

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  1. Buch ; Online: Chapter 2 Viking camps: A historiographical overview

    Williams, Gareth

    2023  

    Schlagwörter Archaeology ; Viking Camps, Ireland, England, Sweden, Frankia, Iberia, winter camps, Viking military camps, Viking Encampment, viking economy, archaeology, Viking archaeology, history, Viking Studies
    Sprache Englisch
    Umfang 1 electronic resource (56 pages)
    Verlag Taylor and Francis
    Dokumenttyp Buch ; Online
    Anmerkung English
    HBZ-ID HT030649414
    ISBN 9781032389530 ; 1032389532
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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  2. Buch ; Online ; E-Book: Biomedical applications of inorganic materials

    Williams, Gareth R.

    (Inorganic materials series ; 10)

    2022  

    Verfasserangabe edited by Gareth R. Williams
    Serientitel Inorganic materials series ; 10
    Überordnung
    Sprache Englisch
    Umfang 1 Online-Ressource (xi, 379 Seiten), Illustrationen, Diagramme
    Verlag Royal Society of Chemistry
    Erscheinungsort Croydon
    Erscheinungsland Vereinigtes Königreich
    Dokumenttyp Buch ; Online ; E-Book
    Bemerkung Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT021261992
    ISBN 978-1-78801-929-3 ; 978-1-78801-930-9 ; 9781788016063 ; 1-78801-929-6 ; 1-78801-930-X ; 1788016068
    DOI 10.1039/9781788019293
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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  3. Buch: Paralysed with fear

    Williams, Gareth

    the story of polio

    2013  

    Verfasserangabe Gareth Williams
    Schlagwörter Poliomyelitis--History ; Poliomyelitis vaccine--History
    Sprache Englisch
    Umfang XVII, 354 S. : Ill., graph. Darst., Kt., 20 cm
    Verlag Palgrave Macmillan
    Erscheinungsort Basingstoke
    Erscheinungsland Vereinigtes Königreich
    Dokumenttyp Buch
    HBZ-ID HT017698787
    ISBN 978-1-137-29975-8 ; 1-137-29975-4
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  4. Buch ; Online: Electrospun and Electrosprayed Formulations for Drug Delivery

    Blagbrough, Ian S. / Williams, Gareth R.

    2019  

    Abstract: This book is comprised of important reviews and cutting-edge original research papers concerning electrospun and electrosprayed formulations in drug delivery. Electrospinning and electrospraying have, in recent years, attracted increasing attention in ... ...

    Abstract This book is comprised of important reviews and cutting-edge original research papers concerning electrospun and electrosprayed formulations in drug delivery. Electrospinning and electrospraying have, in recent years, attracted increasing attention in the pharmaceutical sector, with research in the area advancing rapidly. It is now possible to prepare extremely complex systems using multi-fluid processes, and to increase production rates to an industrial scale. Electrospun formulations can be produced under GMP conditions and are in clinical trials. In this volume, we explore a range of topics around electrospinning and electrospraying in controlled drug delivery. Four reviews cover the exciting potential of cyclodextrin-containing fibers and the many potential biomedical applications of electrospun fibers. The use of electrospinning to prepare amorphous systems and improve the dissolution rate and solubility of poorly soluble active ingredients is addressed, and the possibilities of such materials in tissue engineering are comprehensively covered. The six original research papers cover the effect of molecular properties on API release from Eudragit-based electrospun fibers; ferulic acid solid dispersions; electrospun medicines to treat psoriasis; scale up of electrospinning and its use to produce low-dose tablets; transepithelial permeation of drugs released from electrospun fibers, and the possibilities for the synergistic chemophotothermal treatment of cancer
    Schlagwörter Medicine (General) ; Therapeutics. Pharmacology
    Umfang 1 electronic resource (190 p.)
    Verlag MDPI - Multidisciplinary Digital Publishing Institute
    Erscheinungsort Verlagsort nicht ermittelbar
    Dokumenttyp Buch ; Online
    Anmerkung eng ; Open Access
    HBZ-ID HT020195800
    ISBN 9783038979128 ; 9783038979135 ; 3038979120 ; 3038979139
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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  5. Buch: Angel of death

    Williams, Gareth

    the story of smallpox

    2010  

    Verfasserangabe by Gareth Williams
    Sprache Englisch
    Umfang XIX, 425 S., [4] Bl. : Ill., graph. Darst.
    Verlag Palgrave Macmillan
    Erscheinungsort Basingstoke
    Erscheinungsland Vereinigtes Königreich
    Dokumenttyp Buch
    HBZ-ID HT016377842
    ISBN 978-0-230-27471-6 ; 0-230-27471-4 ; 9780230293199 ; 0230293190
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  6. Buch: Obesity

    Williams, Gareth / Frühbeck, Gema

    science to practice

    2009  

    Verfasserangabe Gareth Williams ; Gema Frühbeck
    Schlagwörter Obesity ; Obesity/Prevention ; Obesity/Treatment
    Thema/Rubrik (Code) 616.398
    Sprache Englisch
    Umfang XVII, 585 S. : zahlr. Ill., graph. Darst.
    Verlag Wiley-Blackwell
    Erscheinungsort Oxford
    Erscheinungsland Vereinigtes Königreich
    Dokumenttyp Buch
    HBZ-ID HT015900445
    ISBN 978-0-470-01911-5 ; 0-470-01911-5
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  7. Buch ; Online: Nanofibres in Drug Delivery

    Luo, C.J. / Raimi-Abraham, Bahijja T. / Williams, Gareth R.

    2018  

    Abstract: In recent years there has been an explosion of interest in the production of nanoscale fibres for drug delivery and tissue engineering. Nanofibres in Drug Delivery aims to outline to new researchers in the field the utility of nanofibres in drug delivery, ...

    Abstract In recent years there has been an explosion of interest in the production of nanoscale fibres for drug delivery and tissue engineering. Nanofibres in Drug Delivery aims to outline to new researchers in the field the utility of nanofibres in drug delivery, and to explain to them how to prepare fibres in the laboratory.The book begins with a brief discussion of the main concepts in pharmaceutical science. The authors then introduce the key techniques that can be used for fibre production and explain briefly the theory behind them. They discuss the experimental implementation of fibre production, starting with the simplest possible set-up and then moving on to consider more complex arrangements. As they do so, they offer advice from their own experience of fibre production, and use examples from current literature to show how each particular type of fibre can be applied to drug delivery. They also consider how fibre production could be moved beyond the research laboratory into industry, discussing regulatory and scale-up aspects
    Schlagwörter Medicine (General) ; Pharmacy and materia medica ; Wirkstofffreisetzung ; Nanofaser
    Schlagwörter Nanofibers ; Nanofibres ; Arzneimittelfreigabe ; Arzneimittelfreisetzung ; Freigabe ; Arzneistofffreisetzung ; Liberation ; Drug delivery ; Medikamentenfreigabe
    Umfang 1 electronic resource (242 p.)
    Verlag UCL Press
    Dokumenttyp Buch ; Online
    Anmerkung English ; Open Access
    HBZ-ID HT020101412
    ISBN 9781787350182 ; 1787350185
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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  8. Artikel ; Online: Influence of upwelling on coral reef benthic communities: a systematic review and meta-analysis.

    Spring, Danielle L / Williams, Gareth J

    Proceedings. Biological sciences

    2023  Band 290, Heft 1995, Seite(n) 20230023

    Abstract: Highly competitive coral reef benthic communities are acutely sensitive to changes in environmental parameters such as temperature and nutrient concentrations. Physical oceanographic processes that induce upwelling therefore act as drivers of community ... ...

    Abstract Highly competitive coral reef benthic communities are acutely sensitive to changes in environmental parameters such as temperature and nutrient concentrations. Physical oceanographic processes that induce upwelling therefore act as drivers of community structure on tropical reefs. How upwelling impacts coral communities, however, is not fully understood; upwelling may provide a natural buffer against climate impacts and could potentially enhance the efficacy of spatial management and reef conservation efforts. This study employed a systematic review to assess existing literature linking upwelling with reef community structure, and a meta-analysis to quantify upwelling impact on the percentage cover of coral reef benthic groups. We show that upwelling has context-dependant effects on the cover of hard coral and fleshy macroalgae, with effect size and direction varying with depth, region and remoteness. Fleshy macroalgae were found to increase by 110% on inhabited reefs yet decrease by 56% around one well-studied remote island in response to upwelling. Hard coral cover was not significantly impacted by upwelling on inhabited reefs but increased by 150% when direct local human pressures were absent. By synthesizing existing evidence, this review facilitates adaptive and nuanced reef management which considers the influence of upwelling on reef assemblages.
    Mesh-Begriff(e) Animals ; Humans ; Coral Reefs ; Anthozoa/physiology ; Seaweed ; Climate ; Nutrients
    Sprache Englisch
    Erscheinungsdatum 2023-03-22
    Erscheinungsland England
    Dokumenttyp Meta-Analysis ; Systematic Review ; Journal Article
    ZDB-ID 209242-6
    ISSN 1471-2954 ; 0080-4649 ; 0962-8452 ; 0950-1193
    ISSN (online) 1471-2954
    ISSN 0080-4649 ; 0962-8452 ; 0950-1193
    DOI 10.1098/rspb.2023.0023
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Shape complementarity at protein interfaces via global docking optimisation.

    Williams, Gareth

    Journal of molecular graphics & modelling

    2018  Band 84, Seite(n) 69–73

    Abstract: Protein complexes are characterised by shape complementarity at the interface. Here we present a simple fast global shape fitting algorithm to investigate the extent to which interfaces are global minima of complementarity. The algorithm is applied to a ... ...

    Abstract Protein complexes are characterised by shape complementarity at the interface. Here we present a simple fast global shape fitting algorithm to investigate the extent to which interfaces are global minima of complementarity. The algorithm is applied to a varied set of hetero and homo complexes and complexes between complexes showing that over 90% of large interfaces are global maxima in the space of shape complementarity.
    Mesh-Begriff(e) Algorithms ; Binding Sites ; Models, Molecular ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Protein Binding ; Protein Conformation ; Proteins/chemistry
    Chemische Substanzen Proteins
    Sprache Englisch
    Erscheinungsdatum 2018-06-15
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 1396450-1
    ISSN 1873-4243 ; 1093-3263
    ISSN (online) 1873-4243
    ISSN 1093-3263
    DOI 10.1016/j.jmgm.2018.06.011
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel ; Online: Extracellular vesicle-embedded materials

    Ma, Yingchang / Brocchini, Steve / Williams, Gareth R.

    Journal of Controlled Release. 2023 Sept., v. 361 p.280-296

    2023  

    Abstract: Extracellular vesicles (EVs) are small membrane-bound vesicles released by cells. EVs are emerging as a promising class of therapeutic entity that could be adapted in formulation due to their lack of immunogenicity and targeting capabilities. EVs have ... ...

    Abstract Extracellular vesicles (EVs) are small membrane-bound vesicles released by cells. EVs are emerging as a promising class of therapeutic entity that could be adapted in formulation due to their lack of immunogenicity and targeting capabilities. EVs have been shown to have similar regenerative and therapeutic effects to their parental cells and also have potential in disease diagnosis. To improve the therapeutic potential of EVs, researchers have developed various strategies for modifying them, including genetic engineering and chemical modifications which have been examined to confer target specificity and prevent rapid clearance after systematic injection. Formulation efforts have focused on utilising hydrogel and nano-formulation strategies to increase the persistence of EV localisation in a specific tissue or organ. Researchers have also used biomaterials or bioscaffolds to deliver EVs directly to disease sites and prolong EV release and exposure. This review provides an in-depth examination of the material design of EV delivery systems, highlighting the impact of the material properties on the molecular interactions and the maintenance of EV stability and function. The various characteristics of materials designed to regulate the stability, release rate and biodistribution of EVs are described. Other aspects of material design, including modification methods to improve the targeting of EVs, are also discussed. This review aims to offer an understanding of the strategies for designing EV delivery systems, and how they can be formulated to make the transition from laboratory research to clinical use.
    Schlagwörter biocompatible materials ; disease diagnosis ; hydrogels ; immunogenicity ; therapeutics ; formulation ; extracellular vesicle ; biomaterial ; scaffold ; stability
    Sprache Englisch
    Erscheinungsverlauf 2023-09
    Umfang p. 280-296.
    Erscheinungsort Elsevier B.V.
    Dokumenttyp Artikel ; Online
    ZDB-ID 632533-6
    ISSN 1873-4995 ; 0168-3659
    ISSN (online) 1873-4995
    ISSN 0168-3659
    DOI 10.1016/j.jconrel.2023.07.059
    Datenquelle NAL Katalog (AGRICOLA)

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