LIVIVO - Das Suchportal für Lebenswissenschaften

switch to English language
Erweiterte Suche

Suchergebnis

Treffer 1 - 3 von insgesamt 3

Suchoptionen

  1. Artikel ; Online: Multicenter Clinical Validation of a Cartridge-Based Real-Time PCR System for Detection of Coccidioides spp. in Lower Respiratory Specimens.

    Saubolle, Michael A / Wojack, Bette R / Wertheimer, Anne M / Fuayagem, Atehkeng Z / Young, Stephen / Koeneman, Brian A

    Journal of clinical microbiology

    2018  Band 56, Heft 2

    Abstract: Available methods for the diagnosis of coccidioidomycosis have significant shortcomings relative to accuracy and timeliness. We retrospectively and prospectively evaluated the diagnostic performance and reproducibility of a new cartridge-based real-time ... ...

    Abstract Available methods for the diagnosis of coccidioidomycosis have significant shortcomings relative to accuracy and timeliness. We retrospectively and prospectively evaluated the diagnostic performance and reproducibility of a new cartridge-based real-time PCR assay for
    Mesh-Begriff(e) Bronchoalveolar Lavage Fluid/microbiology ; Coccidioides/genetics ; Coccidioides/isolation & purification ; Coccidioidomycosis/diagnosis ; Coccidioidomycosis/microbiology ; DNA, Fungal/genetics ; Humans ; Limit of Detection ; Molecular Diagnostic Techniques/methods ; Prospective Studies ; Real-Time Polymerase Chain Reaction/standards ; Reproducibility of Results ; Retrospective Studies ; Sensitivity and Specificity ; Southwestern United States ; Time Factors
    Chemische Substanzen DNA, Fungal
    Sprache Englisch
    Erscheinungsdatum 2018-01-24
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't ; Validation Studies
    ZDB-ID 390499-4
    ISSN 1098-660X ; 0095-1137
    ISSN (online) 1098-660X
    ISSN 0095-1137
    DOI 10.1128/JCM.01277-17
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Verfügbar in ZB MED Köln/Königswinter

    Zs.A 1188: Hefte anzeigen Standort:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  2. Artikel ; Online: Dominance of multidrug resistant CC271 clones in macrolide-resistant streptococcus pneumoniae in Arizona.

    Bowers, Jolene R / Driebe, Elizabeth M / Nibecker, Jennifer L / Wojack, Bette R / Sarovich, Derek S / Wong, Ada H / Brzoska, Pius M / Hubert, Nathaniel / Knadler, Andrew / Watson, Lindsey M / Wagner, David M / Furtado, Manohar R / Saubolle, Michael / Engelthaler, David M / Keim, Paul S

    BMC microbiology

    2012  Band 12, Seite(n) 12

    Abstract: Background: Rates of resistance to macrolide antibiotics in Streptococcus pneumoniae are rising around the world due to the spread of mobile genetic elements harboring mef(E) and erm(B) genes and post-vaccine clonal expansion of strains that carry them.! ...

    Abstract Background: Rates of resistance to macrolide antibiotics in Streptococcus pneumoniae are rising around the world due to the spread of mobile genetic elements harboring mef(E) and erm(B) genes and post-vaccine clonal expansion of strains that carry them.
    Results: Characterization of 592 clinical isolates collected in Arizona over a 10 year period shows 23.6% are macrolide resistant. The largest portion of the macrolide-resistant population, 52%, is dual mef(E)/erm(B)-positive. All dual-positive isolates are multidrug-resistant clonal lineages of Taiwan19F-14, mostly multilocus sequence type 320, carrying the recently described transposon Tn2010. The remainder of the macrolide resistant S. pneumoniae collection includes 31% mef(E)-positive, and 9% erm(B)-positive strains.
    Conclusions: The dual-positive, multidrug-resistant S. pneumoniae clones have likely expanded by switching to non-vaccine serotypes after the heptavalent pneumococcal conjugate vaccine release, and their success limits therapy options. This upsurge could have a considerable clinical impact in Arizona.
    Mesh-Begriff(e) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Anti-Bacterial Agents/pharmacology ; Arizona/epidemiology ; Child ; Child, Preschool ; Cluster Analysis ; DNA Transposable Elements ; Drug Resistance, Multiple, Bacterial ; Female ; Genes, Bacterial ; Genotype ; Humans ; Infant ; Macrolides/pharmacology ; Male ; Middle Aged ; Molecular Epidemiology ; Multilocus Sequence Typing ; Pneumococcal Infections/epidemiology ; Pneumococcal Infections/microbiology ; Polymerase Chain Reaction ; Streptococcus pneumoniae/classification ; Streptococcus pneumoniae/drug effects ; Streptococcus pneumoniae/genetics ; Streptococcus pneumoniae/isolation & purification ; Young Adult
    Chemische Substanzen Anti-Bacterial Agents ; DNA Transposable Elements ; Macrolides
    Sprache Englisch
    Erscheinungsdatum 2012-01-18
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, N.I.H., Extramural
    ISSN 1471-2180
    ISSN (online) 1471-2180
    DOI 10.1186/1471-2180-12-12
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

    Fernleihe an ZB MED

    Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

  3. Artikel ; Online: Dominance of multidrug resistant CC271 clones in macrolide-resistant streptococcus pneumoniae in Arizona

    Bowers Jolene R / Driebe Elizabeth M / Nibecker Jennifer L / Wojack Bette R / Sarovich Derek S / Wong Ada H / Brzoska Pius M / Hubert Nathaniel / Knadler Andrew / Watson Lindsey M / Wagner David M / Furtado Manohar R / Saubolle Michael / Engelthaler David M / Keim Paul S

    BMC Microbiology, Vol 12, Iss 1, p

    2012  Band 12

    Abstract: Abstract Background Rates of resistance to macrolide antibiotics in Streptococcus pneumoniae are rising around the world due to the spread of mobile genetic elements harboring mef (E) and erm (B) genes and post-vaccine clonal expansion of strains that ... ...

    Abstract Abstract Background Rates of resistance to macrolide antibiotics in Streptococcus pneumoniae are rising around the world due to the spread of mobile genetic elements harboring mef (E) and erm (B) genes and post-vaccine clonal expansion of strains that carry them. Results Characterization of 592 clinical isolates collected in Arizona over a 10 year period shows 23.6% are macrolide resistant. The largest portion of the macrolide-resistant population, 52%, is dual mef (E)/ erm (B)-positive. All dual-positive isolates are multidrug-resistant clonal lineages of Taiwan 19F -14, mostly multilocus sequence type 320, carrying the recently described transposon Tn 2010 . The remainder of the macrolide resistant S. pneumoniae collection includes 31% mef (E)-positive, and 9% erm (B)-positive strains. Conclusions The dual-positive, multidrug-resistant S. pneumoniae clones have likely expanded by switching to non-vaccine serotypes after the heptavalent pneumococcal conjugate vaccine release, and their success limits therapy options. This upsurge could have a considerable clinical impact in Arizona.
    Schlagwörter Microbiology ; QR1-502 ; Science ; Q ; DOAJ:Microbiology ; DOAJ:Biology ; DOAJ:Biology and Life Sciences
    Sprache Englisch
    Erscheinungsdatum 2012-01-01T00:00:00Z
    Verlag BioMed Central
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Volltext online

    Zusatzmaterialien

    Kategorien

    Fernleihe an ZB MED

    Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

Zum Seitenanfang