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  1. Artikel: [Rectal adenocarcinoma coexisting with metastatic small intestinal stromal tumor: case report and literature review].

    Liu, X L / Gao, J / Xu, Z / Lyu, C X / Yang, M D

    Zhonghua zhong liu za zhi [Chinese journal of oncology

    2022  Band 43, Heft 11, Seite(n) 1221–1222

    Mesh-Begriff(e) Adenocarcinoma ; Gastrointestinal Stromal Tumors ; Humans ; Intestinal Neoplasms ; Rectal Neoplasms
    Sprache Chinesisch
    Erscheinungsdatum 2022-01-21
    Erscheinungsland China
    Dokumenttyp Case Reports ; Journal Article ; Review
    ZDB-ID 603424-x
    ISSN 0253-3766
    ISSN 0253-3766
    DOI 10.3760/cma.j.cn112152-20200526-00487
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel: [Summary of clinical research progression of apatinib combined with docetaxel in second-line treatment of advanced gastric cancer].

    Yang, M D / Gao, J / Liu, X L / Yang, W H / Lu, H X

    Zhonghua zhong liu za zhi [Chinese journal of oncology

    2020  Band 42, Heft 7, Seite(n) 594–597

    Abstract: Objective: ...

    Abstract Objective:
    Mesh-Begriff(e) Antineoplastic Agents/therapeutic use ; Disease Progression ; Docetaxel/therapeutic use ; Humans ; Pyridines/therapeutic use ; Stomach Neoplasms/drug therapy
    Chemische Substanzen Antineoplastic Agents ; Pyridines ; Docetaxel (15H5577CQD) ; apatinib (5S371K6132)
    Sprache Chinesisch
    Erscheinungsdatum 2020-08-25
    Erscheinungsland China
    Dokumenttyp Journal Article
    ZDB-ID 603424-x
    ISSN 0253-3766
    ISSN 0253-3766
    DOI 10.3760/cma.j.cn112152-20190121-00027
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Improving rowing performance by adjusting oar blade size and angle.

    van Nieuwburg, W C A M / van Spreuwel, B J J / Tran, M T K / Yang, M D / Greidanus, A / Mulder, G / Tummers, M J / Westerweel, J / Suijker, W / van Wijk, R

    Frontiers in sports and active living

    2023  Band 5, Seite(n) 1109494

    Abstract: The principal aim of the work presented here is to investigate and demonstrate that a forward tilted rowing blade would result in a more efficient and effective motion of the blade through the water that would result in a higher boat speed when an equal ... ...

    Abstract The principal aim of the work presented here is to investigate and demonstrate that a forward tilted rowing blade would result in a more efficient and effective motion of the blade through the water that would result in a higher boat speed when an equal input power is provided. A 1:5 scaled rowing boat is used to determine the performance of rowing blades with different sizes and blade angles. This is used to validate the results of a previous study where the optimal blade angle of 15
    Sprache Englisch
    Erscheinungsdatum 2023-03-09
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ISSN 2624-9367
    ISSN (online) 2624-9367
    DOI 10.3389/fspor.2023.1109494
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel: [Development and application syndromic surveillance and early warning system in border area in Yunnan Province].

    Song, X X / Cai, L / Liu, W / Cui, W L / Peng, X / Li, Q F / Dong, Y / Yang, M D / Wu, B Q / Yue, T K / Fan, J H / Li, Y Y / Li, Y

    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi

    2023  Band 44, Heft 5, Seite(n) 845–850

    Abstract: Objective: ...

    Abstract Objective:
    Mesh-Begriff(e) Humans ; Influenza, Human ; Sentinel Surveillance ; Syndrome ; China ; Cell Phone
    Sprache Chinesisch
    Erscheinungsdatum 2023-05-23
    Erscheinungsland China
    Dokumenttyp English Abstract ; Journal Article
    ZDB-ID 645026-x
    ISSN 0254-6450
    ISSN 0254-6450
    DOI 10.3760/cma.j.cn112338-20221013-00882
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel: [Analysis of occupational health surveillance of workers exposed to benzenemethylbenzene and dimethylbenzene].

    Bai, L / Yang, H Y / Cai, W H / Bi, J / Luo, H / Yang, M D

    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases

    2019  Band 37, Heft 6, Seite(n) 473–475

    Mesh-Begriff(e) Benzene Derivatives/analysis ; Humans ; Occupational Exposure/analysis ; Population Surveillance ; Xylenes/analysis
    Chemische Substanzen Benzene Derivatives ; Xylenes
    Sprache Chinesisch
    Erscheinungsdatum 2019-06-29
    Erscheinungsland China
    Dokumenttyp Journal Article
    ISSN 1001-9391
    ISSN 1001-9391
    DOI 10.3760/cma.j.issn.1001-9391.2019.06.019
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel: Clinical Features of 69 Cases with Coronavirus Disease 2019 in Wuhan, China ;Clinical Infectious Diseases ;Oxford Academic

    Zhongliang Wang, M. D. Bohan Yang M. D. Qianwen Li M. D. Lu Wen M. D. Ruiguang Zhang M. D.

    Clinical Infectious Diseases

    Abstract: Abstract Background From December 2019 to February 2020, 2019 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a serious outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China Related clinical features are needed Methods ... ...

    Abstract Abstract Background From December 2019 to February 2020, 2019 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a serious outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China Related clinical features are needed Methods We reviewed 69 patients who were hospitalized in Union hospital in Wuhan between January 16 to January 29, 2020 All patients were confirmed to be infected with SARS-CoV-2 and the final date of follow-up was February 4, 2020 Results The median age of 69 enrolled patients was 42 0 years (IQR 35 0-62 0), and 32 patients (46%) were men The most common symptoms were fever (60[87%]), cough (38[55%]), and fatigue (29[42%]) Most patients received antiviral therapy (66 [98 5%] of 67 patients) and antibiotic therapy (66 [98 5%] of 67 patients) As of February 4, 2020, 18 (26 9%) of 67 patients had been discharged, and five patients had died, with a mortality rate of 7 5% According to the lowest SpO2 during admission, cases were divided into the SpO2≥90% group (n=55) and the SpO2<90% group (n=14) All 5 deaths occurred in the SpO2<90% group Compared with SpO2≥90% group, patients of the SpO2<90% group were older, and showed more comorbidities and higher plasma levels of IL6, IL10, lactate dehydrogenase, and c reactive protein Arbidol treatment showed tendency to improve the discharging rate and decrease the mortality rate Conclusions COVID-19 appears to show frequent fever, dry cough, and increase of inflammatory cytokines, and induced a mortality rate of 7 5% Older patients or those with underlying comorbidities are at higher risk of death
    Schlagwörter covid19
    Verlag WHO
    Dokumenttyp Artikel
    Anmerkung WHO #Covidence: #8628
    Datenquelle COVID19

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  7. Artikel ; Online: Lack of CD47 on Donor Hepatocytes Promotes Innate Immune Cell Activation and Graft Loss

    Nalu Navarro-Alvarez / Yong-Guang Yang M.D., Ph.D.

    Cell Transplantation, Vol

    A Potential Barrier to Hepatocyte Xenotransplantation

    2014  Band 23

    Abstract: We have previously shown that interspecies incompatibility of CD47 plays an important role in triggering rejection of xenogeneic hematopoietic cells by macrophages. However, whether CD47 incompatibility also induces rejection of nonhematopoietic cellular ...

    Abstract We have previously shown that interspecies incompatibility of CD47 plays an important role in triggering rejection of xenogeneic hematopoietic cells by macrophages. However, whether CD47 incompatibility also induces rejection of nonhematopoietic cellular xenografts remains unknown. Herein, we have addressed this question in a mouse model of hepatocyte transplantation in which CD47 -/- hepatocytes were used to resemble xenografts for CD47 incompatibility. We show that intrasplenic transplantation of CD47 -/- , but not wild-type (WT) hepatocytes, into partially hepatectomized syngeneic WT mice resulted in a rapid increase in Mac-1 + cells with an activation phenotype (i.e., Mac-1 + CD14 + and Mac-1 + CD16/32 high ), compared to nontransplant controls. In addition, CD47 -/- hepatocytes were more severely damaged than WT hepatocytes as indicated by the greater AST and ALT serum levels in these mice. Furthermore, long-term donor hepatocyte survival and liver repopulation were observed in mice receiving WT hepatocytes, whereas CD47 -/- hepatocytes were completely rejected within 2 weeks. These results suggest that CD47 on donor hepatocytes prevents recipient myeloid innate immune cell activation, hence aiding in graft survival after hepatocyte transplantation. Thus, CD47 incompatibility is likely to present an additional barrier to hepatocyte xenotransplantation.
    Schlagwörter Medicine ; R
    Thema/Rubrik (Code) 610
    Sprache Englisch
    Erscheinungsdatum 2014-04-01T00:00:00Z
    Verlag SAGE Publishing
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  8. Artikel: Automation model of sewerage rehabilitation planning.

    Yang, M D / Su, T C

    Water science and technology : a journal of the International Association on Water Pollution Research

    2007  Band 54, Heft 11-12, Seite(n) 225–232

    Abstract: The major steps of sewerage rehabilitation include inspection of sewerage, assessment of structural conditions, computation of structural condition grades, and determination of rehabilitation methods and materials. Conventionally, sewerage rehabilitation ...

    Abstract The major steps of sewerage rehabilitation include inspection of sewerage, assessment of structural conditions, computation of structural condition grades, and determination of rehabilitation methods and materials. Conventionally, sewerage rehabilitation planning relies on experts with professional background that is tedious and time-consuming. This paper proposes an automation model of planning optimal sewerage rehabilitation strategies for the sewer system by integrating image process, clustering technology, optimization, and visualization display. Firstly, image processing techniques, such as wavelet transformation and co-occurrence features extraction, were employed to extract various characteristics of structural failures from CCTV inspection images. Secondly, a classification neural network was established to automatically interpret the structural conditions by comparing the extracted features with the typical failures in a databank. Then, to achieve optimal rehabilitation efficiency, a genetic algorithm was used to determine appropriate rehabilitation methods and substitution materials for the pipe sections with a risk of mal-function and even collapse. Finally, the result from the automation model can be visualized in a geographic information system in which essential information of the sewer system and sewerage rehabilitation plans are graphically displayed. For demonstration, the automation model of optimal sewerage rehabilitation planning was applied to a sewer system in east Taichung, Chinese Taiwan.
    Mesh-Begriff(e) Automation/methods ; Equipment Failure ; Geography ; Humans ; Sewage ; Taiwan ; Urban Population ; Waste Disposal, Fluid/instrumentation ; Waste Disposal, Fluid/methods
    Chemische Substanzen Sewage
    Sprache Englisch
    Erscheinungsdatum 2007-01-06
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 764273-8
    ISSN 1996-9732 ; 0273-1223
    ISSN (online) 1996-9732
    ISSN 0273-1223
    DOI 10.2166/wst.2006.805
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Massive upper gastrointestinal bleeding caused by an intercostal arterio-esophageal fistula

    Kai-Chun Yang, M.D. / Men-Ying Lin, M.D. / Li-Ting Huang, M.D. / Wei-Lun Chang, M.D., Ph.D.

    Radiology Case Reports, Vol 15, Iss 10, Pp 2026-

    A rare case report

    2020  Band 2030

    Abstract: Arterio-esophageal fistula (AEF) is a rare life-threatening cause of upper gastrointestinal bleeding. Realizing the risk factors and clinical presentations of AEF will enable us to provide timely diagnosis, efficient treatment, and better outcome. We ... ...

    Abstract Arterio-esophageal fistula (AEF) is a rare life-threatening cause of upper gastrointestinal bleeding. Realizing the risk factors and clinical presentations of AEF will enable us to provide timely diagnosis, efficient treatment, and better outcome. We present a 43-year-old Taiwanese man who had histories of destructive lung, innominate artery-trachea fistula, and received bilobectomy. He was admitted to our hospital with fresh blood drainage from nasogastric tube. He was diagnosed as right fifth intercostal artery esophageal fistula by computed tomography angiography and transcatheter arterial embolization was performed. The bleeding stopped and the patient was discharged uneventfully. The risk factors of AEF include esophageal foreign body, vascular surgery, thoracic arterial malformations, and concurrent chemoradiotherapy in T4-esophageal cancer. Computed tomography angiography may be the most sensitive diagnostic test. Transcatheter arterial embolization or endovascular stent grafting may be considered as the first-line treatment of AEF in the future.
    Schlagwörter Arterio-esophageal fistula ; Intercostal artery ; Transcatheter arterial embolization ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
    Thema/Rubrik (Code) 610
    Sprache Englisch
    Erscheinungsdatum 2020-10-01T00:00:00Z
    Verlag Elsevier
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  10. Artikel ; Online: The CnB1 p.D102A variant is linked to dilated cardiomyopathy via impaired Calcineurin activity.

    Jinqiang Zhuang, M D / Ruijun Yuan, M D / Yizeng, M D / Congliang Miao, M D / Dandan Zhou, M D / Anli Na, M D / Xinying Yang, M D / Hui Xu, M D / Hong, Jiang

    Journal of molecular and cellular cardiology

    2020  Band 148, Seite(n) 15–24

    Abstract: Background: The role of calcineurin (protein phosphatase 2B (PP2B)) in the pathogenesis of human dilated cardiomyopathy (DCM) has not been fully elucidated. We determined the potential involvement of calcineurin in the pathogenesis of DCM caused by ... ...

    Abstract Background: The role of calcineurin (protein phosphatase 2B (PP2B)) in the pathogenesis of human dilated cardiomyopathy (DCM) has not been fully elucidated. We determined the potential involvement of calcineurin in the pathogenesis of DCM caused by mutations in CnB1, a subunit of calcineurin.
    Methods: By whole-exome sequencing, we identified a new CnB1 variant in a Han Chinese proband with cardiomyopathy from a 3-generation family with 2 normal individuals and 3 individuals with familial dilated cardiomyopathy. The potential pathogenic variant was validated by Sanger sequencing. We performed functional and mechanistic experiments in a CnB1-knockin (KI) mouse model and at the cellular level.
    Results: We detected a rare heterozygous CnB1 variant (p.D102A) in a proband with dilated cardiomyopathy. This variant was localized to the EF hand 3 region of CnB1, where no variants have been previously reported. KI mice harboring the p.D102A variant exhibited decreased cardiac function and cardiac dilatation. Immunoblotting, RT-PCR and immunofluorescence results showed decreased cardiomyocyte size and heart failure-related protein expression. A calcineurin activity assay demonstrated decreased calcineurin activity in the KI mice, accompanied by the decreased ability of CnB1 to bind CnA.
    Conclusions: CnB1 p.D102A is a disease-associated variant that confers susceptibility to cardiac dilatation. This variant is associated with impaired calcineurin activity and a subsequent decrease in the ability of CnB1 to bind CnA.
    Mesh-Begriff(e) Amino Acid Sequence ; Animals ; Base Sequence ; Calcineurin/chemistry ; Calcineurin/genetics ; Cardiomyopathy, Dilated/genetics ; Cardiomyopathy, Dilated/physiopathology ; Gene Expression Regulation ; Gene Knock-In Techniques ; Humans ; Mice ; Mutation/genetics ; Phenotype ; Protein Binding ; Protein Subunits/genetics
    Chemische Substanzen Protein Subunits ; Calcineurin (EC 3.1.3.16) ; PPP3R1 protein, human (EC 3.1.3.16)
    Sprache Englisch
    Erscheinungsdatum 2020-08-31
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 80157-4
    ISSN 1095-8584 ; 0022-2828
    ISSN (online) 1095-8584
    ISSN 0022-2828
    DOI 10.1016/j.yjmcc.2020.08.012
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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