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  1. Artikel ; Online: Seroprevalence of avian influenza H9 virus in poultry-shop workers and customers in Rawalpindi, Pakistan

    Saima Dil / Zafar Hayat Maken / Muhammad Athar Abbas

    Journal of Infection and Public Health, Vol 13, Iss 3, Pp 462- (2020)

    2020  

    Schlagwörter Infectious and parasitic diseases ; RC109-216 ; Public aspects of medicine ; RA1-1270
    Sprache Englisch
    Erscheinungsdatum 2020-03-01T00:00:00Z
    Verlag Elsevier
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  2. Artikel ; Online: GENEXPERT ® TECHNOLOGY A BREAKTHROUGH FOR DIAGNOSIS OF TUBERCULOUS PERICARDITIS AND PLEURITIS IN LESS THAN TWO HOURS

    Hamid Mahmood / Talmeez Zaib / Zafar Hayat Maken

    Journal of University Medical & Dental College, Vol 9, Iss

    2018  Band 3

    Abstract: ABSTRACT: BACKGROUND: Diagnosis of Tubercles Pericarditis and Pleuritis remains the greatest challenge for clinicians. WHO has recommended GeneXpert MTB/RIF assay as a screening test for substitution of conventional methods for the initial diagnosis and ... ...

    Abstract ABSTRACT: BACKGROUND: Diagnosis of Tubercles Pericarditis and Pleuritis remains the greatest challenge for clinicians. WHO has recommended GeneXpert MTB/RIF assay as a screening test for substitution of conventional methods for the initial diagnosis and prognosis of the extra pulmonary and pulmonary tuberculosis in developing countries. OBJECTIVE: To find out the diagnostic validity of GeneXpert assay for detection of Myco-bacterium tuberculosis in the pericardial and pleural effusion samples, keeping MTB culture as “Gold Standard”. MATERIAL AND METHODS: The total number of 286 samples of effusions (pericardial 128, pleural 158) were received, and processed for Zn smear microscopy, LJ culture, GeneXpert MTB/RIF assay according to standard protocols. Efficacy for the detection of MTB was evaluated comparatively. RESULTS: Out of 286 effusions samples AFB was detected by Zn smear in 11 (3.8%) samples while GeneXpert detected MTB in 43 (15.0%) and LJ culture 51 (17.8%). Zn smear showed sensitivity 18.2% , specificity , 98.1% , Positive predictive value 81.8% , Negative predictive value 85.4 % , in comparison GeneXpert showed high sensitivity 84.3%, specificity 100%, with Positive predictive value 100% and Negative predictive value 96.7%. CONCLUSION: GeneXpert assay is an innovative tool in resource limited settings for prompt detection of MTB along with drug résistance. It is definitely an attractive point of care testing, with high sensitivity and specificity along with turnout time of two hours, which facilitates timely diagnoses and appropriate management of tuberculous Pleuritis and Pericarditis.
    Schlagwörter GeneXpert MTB/RIF assay ; Pleural effusions ; pericardial effusion ; LJ culture ; Medicine ; R
    Thema/Rubrik (Code) 630
    Sprache Englisch
    Erscheinungsdatum 2018-09-01T00:00:00Z
    Verlag University of Faisalabad
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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