Artikel ; Online: Considering a Biologic: What's a Clinician to Do? Screening and Laboratory Monitoring for Biologic Therapies in the Treatment of Psoriasis.
2022 Band 20, Heft 1, Seite(n) 14–17
Abstract: Biologic therapies have revolutionized the treatment of psoriasis; however, these immunomodulatory therapies may increase the risk of reactivation of latent and chronic infections. Tumor necrosis factor alpha (TNF-α) inhibitors, in particular, have been ... ...
Abstract | Biologic therapies have revolutionized the treatment of psoriasis; however, these immunomodulatory therapies may increase the risk of reactivation of latent and chronic infections. Tumor necrosis factor alpha (TNF-α) inhibitors, in particular, have been associated with the increased risk of reactivation of tuberculosis (TB) in patients with latent TB, as well as hepatitis B virus (HBV), in patients with chronic HBV infections. Currently, baseline TB tests are the only screening tests supported with strong evidence. High-grade evidence for HBV screening tests is lacking; however, these tests are sometimes performed in clinical practice. We describe current recommendations for screening tests prior to the initiation of biologic therapy. |
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Mesh-Begriff(e) | Biological Therapy ; Hepatitis B virus/physiology ; Humans ; Immunologic Factors/therapeutic use ; Latent Tuberculosis/complications ; Latent Tuberculosis/diagnosis ; Psoriasis/complications ; Psoriasis/drug therapy ; Tumor Necrosis Factor-alpha |
Chemische Substanzen | Immunologic Factors ; Tumor Necrosis Factor-alpha |
Sprache | Englisch |
Erscheinungsdatum | 2022-02-28 |
Erscheinungsland | United States |
Dokumenttyp | Journal Article |
ZDB-ID | 2171125-2 |
ISSN | 1751-7125 ; 1540-9740 |
ISSN (online) | 1751-7125 |
ISSN | 1540-9740 |
Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
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