Artikel: Blood biomarker for Parkinson disease: peptoids.
2016 Band 2
Abstract: Parkinson disease (PD) is the second most common neurodegenerative disease. Because dopaminergic neuronal loss begins years before motor symptoms appear, a biomarker for the early identification of the disease is critical for the study of putative ... ...
Abstract | Parkinson disease (PD) is the second most common neurodegenerative disease. Because dopaminergic neuronal loss begins years before motor symptoms appear, a biomarker for the early identification of the disease is critical for the study of putative neuroprotective therapies. Brain imaging of the nigrostriatal dopamine system has been used as a biomarker for early disease along with cerebrospinal fluid analysis of α-synuclein, but a less costly and relatively non-invasive biomarker would be optimal. We sought to identify an antibody biomarker in the blood of PD patients using a combinatorial peptoid library approach. We examined serum samples from 75 PD patients, 25 |
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Sprache | Englisch |
Erscheinungsdatum | 2016-06-23 |
Erscheinungsland | United States |
Dokumenttyp | Journal Article |
ZDB-ID | 2819218-7 |
ISSN | 2373-8057 |
ISSN | 2373-8057 |
DOI | 10.1038/npjparkd.2016.12 |
Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
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