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  1. Artikel ; Online: Antitumor Effects of Dietary Compounds.

    Bhutta, Zeeshan Ahmad / Choi, Kyung-Chul

    Nutrients

    2023  Band 15, Heft 10

    Abstract: Cancer is reported to be a major cause of death worldwide, accounting for 10 million in 2020 based on 19 [ ... ]. ...

    Abstract Cancer is reported to be a major cause of death worldwide, accounting for 10 million in 2020 based on 19 [...].
    Mesh-Begriff(e) Humans ; Diet ; Neoplasms/drug therapy ; Global Health
    Sprache Englisch
    Erscheinungsdatum 2023-05-17
    Erscheinungsland Switzerland
    Dokumenttyp Editorial
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu15102349
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Effects of isoflurane and xylazine on inducing cerebral ischemia by the model of middle cerebral artery occlusion in mice

    Jinyoung Won / Zeeshan Ahmad Khan / Yonggeun Hong

    Laboratory Animal Research, Vol 39, Iss 1, Pp 1-

    2023  Band 7

    Abstract: Abstract Preclinical ischemic stroke studies extensively utilize the intraluminal suture method of middle cerebral artery occlusion (MCAo). General anesthesia administration is an essential step for MCAo, but anesthetic agents can lead to adverse effects ...

    Abstract Abstract Preclinical ischemic stroke studies extensively utilize the intraluminal suture method of middle cerebral artery occlusion (MCAo). General anesthesia administration is an essential step for MCAo, but anesthetic agents can lead to adverse effects causing death and making a considerable impact on inducing cerebral ischemia. The purpose of this study was to comparatively assess the effect of isoflurane and xylazine on transient cerebral ischemia in a mouse model of MCAo. Twenty animals were randomly divided into four groups: sham group (no MCAo), control group (MCAo under isoflurane, no agent till reperfusion), isoflurane group (MCAo under isoflurane continued till reperfusion), xylazine group (MCAo under isoflurane, and administration of xylazine till reperfusion). The survival rate, brain infarct volume, and neurologic deficits were studied to assess the effect of isoflurane and xylazine on the stroke model. Our results showed that the body weight showed statistically significant change before and 24 h after surgery in the control and Isoflurane groups, but no difference in the Xylazine group. Also, the survival rate, brain infarct volume, and neurologic deficits were slightly reduced in the isoflurane group at 24 h after reperfusion injury. However, the xylazine and control groups showed similar BIV and neurologic deficits. Interestingly, a high survival rate was observed in the xylazine group. Our results indicate that the modified method of inhalation anesthetics combined with xylazine can reduce the risk of mortality and develop a reproducible MCAo model with predictable brain ischemia. In addition, extended isoflurane anesthesia after MCAo is associated with the risk of mortality.
    Schlagwörter Anesthesia ; Middle cerebral artery occlusion ; Ischemic stroke ; Isoflurane ; Xylazine ; Medicine (General) ; R5-920 ; Biology (General) ; QH301-705.5
    Thema/Rubrik (Code) 610 ; 630
    Sprache Englisch
    Erscheinungsdatum 2023-06-01T00:00:00Z
    Verlag BMC
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  3. Artikel ; Online: Antimicrobial activity of comfort related properties of silk treated with herbal extracts in making of reusable masks

    Shama Sadaf / Neelma Munir / Ayesha Saeed / Komal Hassan / Zeeshan Ahmad

    Bioscience Journal, Vol 39, Pp e39035-e

    2023  Band 39035

    Abstract: The study was aimed at divulging an eco-friendly antimicrobial finish on 100 % silk woven fabric. The leaves’ extract of Azadirachata indica, Butea monosperma and Litche chinensis were used as the development of eco-friendly antimicrobial finish. The ... ...

    Abstract The study was aimed at divulging an eco-friendly antimicrobial finish on 100 % silk woven fabric. The leaves’ extract of Azadirachata indica, Butea monosperma and Litche chinensis were used as the development of eco-friendly antimicrobial finish. The antimicrobial property and comfort related property were checked before and after applying antimicrobial finish. In comfort related property absorbency & air permeability were checked. The ASTEM E2149 Shake Flask method was used to check antimicrobial finish and AATCC method was used for checking fabric property. One way ANOVA statistical test was applied for analysis of results. The FTIR and SEM results showed the presences of finish on fabrics. In comfort related property, absorbency and air permeability was increased. The results showed that antimicrobial finish made 100% reduction against microorganism up to 25 washes which can be used in making reusable masks fight against COVID- 19.
    Schlagwörter antimicrobial ; azadirachata indica ; butea monosperma ; litchi chinensis ; silk ; Agriculture ; S ; Biology (General) ; QH301-705.5
    Thema/Rubrik (Code) 690
    Sprache Englisch
    Erscheinungsdatum 2023-03-01T00:00:00Z
    Verlag Universidade Federal de Uberlândia
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  4. Artikel: Effects of isoflurane and xylazine on inducing cerebral ischemia by the model of middle cerebral artery occlusion in mice.

    Won, Jinyoung / Khan, Zeeshan Ahmad / Hong, Yonggeun

    Laboratory animal research

    2023  Band 39, Heft 1, Seite(n) 11

    Abstract: Preclinical ischemic stroke studies extensively utilize the intraluminal suture method of middle cerebral artery occlusion (MCAo). General anesthesia administration is an essential step for MCAo, but anesthetic agents can lead to adverse effects causing ... ...

    Abstract Preclinical ischemic stroke studies extensively utilize the intraluminal suture method of middle cerebral artery occlusion (MCAo). General anesthesia administration is an essential step for MCAo, but anesthetic agents can lead to adverse effects causing death and making a considerable impact on inducing cerebral ischemia. The purpose of this study was to comparatively assess the effect of isoflurane and xylazine on transient cerebral ischemia in a mouse model of MCAo. Twenty animals were randomly divided into four groups: sham group (no MCAo), control group (MCAo under isoflurane, no agent till reperfusion), isoflurane group (MCAo under isoflurane continued till reperfusion), xylazine group (MCAo under isoflurane, and administration of xylazine till reperfusion). The survival rate, brain infarct volume, and neurologic deficits were studied to assess the effect of isoflurane and xylazine on the stroke model. Our results showed that the body weight showed statistically significant change before and 24 h after surgery in the control and Isoflurane groups, but no difference in the Xylazine group. Also, the survival rate, brain infarct volume, and neurologic deficits were slightly reduced in the isoflurane group at 24 h after reperfusion injury. However, the xylazine and control groups showed similar BIV and neurologic deficits. Interestingly, a high survival rate was observed in the xylazine group. Our results indicate that the modified method of inhalation anesthetics combined with xylazine can reduce the risk of mortality and develop a reproducible MCAo model with predictable brain ischemia. In addition, extended isoflurane anesthesia after MCAo is associated with the risk of mortality.
    Sprache Englisch
    Erscheinungsdatum 2023-06-01
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2623220-0
    ISSN 2233-7660 ; 1738-6055
    ISSN (online) 2233-7660
    ISSN 1738-6055
    DOI 10.1186/s42826-023-00163-6
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Hyperspectral image reconstruction from colored natural flame luminosity imaging in a tri-fuel optical engine

    Qiang Cheng / Shervin Karimkashi / Zeeshan Ahmad / Ossi Kaario / Ville Vuorinen / Martti Larmi

    Scientific Reports, Vol 13, Iss 1, Pp 1-

    2023  Band 18

    Abstract: Abstract The detection of chemiluminescence from various radicals and molecules in a hydrocarbon flame can provide valuable information on the rate of local heat release, combustion stability, and combustion completeness. In this study, chemiluminescence ...

    Abstract Abstract The detection of chemiluminescence from various radicals and molecules in a hydrocarbon flame can provide valuable information on the rate of local heat release, combustion stability, and combustion completeness. In this study, chemiluminescence from the combustion process is detected using a high-speed color camera within the broadband spectrum of visible light. Whereon, a novel hyperspectral reconstruction approach based on the physically plausible spectral reconstruction (PPSR) is employed to reconstruct the spectral chemiluminescence signals from 400 to 700 nm with a resolution of 10 nm to provide 31 different spectral channels. The reconstructed key chemiluminescence signals (e.g., CH*, CH2O*, C2*, and CO2*) from the color images are further analyzed to characterize the chemical kinetics and combustion processes under engine conditions. The spectral chemiluminescence evolution with engine crank angle is identified to comprehend the effect of H2 fraction on flame characteristics and combustion kinetics. Additionally, in this study, a detailed kinetic mechanism is adopted to deepen the theoretical understanding and describe the spectral chemiluminescence from H2/CH4 and H2/CH4/n-dodecane flames at relevant conditions for various species including OH*, CH*, C2*, and CO2*. The results indicate that the PPSR is an adequately reliable approach to reconstructing spectral wavelengths based on chemiluminescence signals from the color images, which can potentially provide qualitative information about the evolution of various species during combustion. Here, the reconstructed chemiluminescence images show less than 1% errors compared to the raw images in red, green, and blue channels. Furthermore, the reconstructed chemiluminescence trends of CH*, CH2O*, C2*, and CO2* show a good agreement with the detailed kinetics 0D simulation.
    Schlagwörter Medicine ; R ; Science ; Q
    Thema/Rubrik (Code) 571
    Sprache Englisch
    Erscheinungsdatum 2023-02-01T00:00:00Z
    Verlag Nature Portfolio
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  6. Artikel ; Online: A Bibliometric Analysis of Studies on Plant Endemism during the Period of 1991–2022

    Zishan Ahmad Wani / Fareeda Akhter / Qamer Ridwan / Yashwant S. Rawat / Zeeshan Ahmad / Shreekar Pant

    Journal of Zoological and Botanical Gardens, Vol 4, Iss 4, Pp 692-

    2023  Band 710

    Abstract: A bibliometric analysis of 349 scholarly documents published on the topic plant nativity and endemism from 1991–2022 was carried out using the ‘bibliometrix’ tool, developed through the R programming language. The results revealed a significant increase ... ...

    Abstract A bibliometric analysis of 349 scholarly documents published on the topic plant nativity and endemism from 1991–2022 was carried out using the ‘bibliometrix’ tool, developed through the R programming language. The results revealed a significant increase in the number of publications on plant nativity and endemism research since 1991. Of the total of 349 documents that were analyzed, 38 are single authored documents, and the average number of documents per author is 0.278. Each document has received an average of 33.67 citations, with 3.18 citations per year per document. The relationship between the number of authors and the number of articles that they have published follows a power-law distribution. Based on Bradford’s law, only eight were found to be the core sources. Mexico, followed by the USA, has produced the highest number of documents on plant nativity and endemism. The present study suggests that it is necessary to categorize data on endemism by floristic provinces, not by political subdivisions. Synecological studies are also needed, since endemic plants exist within communities. Models that accurately predict levels of endemism on the basis of easily measurable environmental variables should be useful for the rapid identification of endemic-rich areas. Recognition of the importance of plant endemism and the implementation of conservation measures is crucial for preserving biodiversity hotspots. Both in situ and ex situ conservation efforts are essential for protecting endemic species and preventing their extinction. By integrating these approaches, we can contribute to the long-term conservation and management of endemic plant species.
    Schlagwörter endemism ; biblioshiny ; web of science ; Bradford’s law ; conservation ; Biology (General) ; QH301-705.5 ; Zoology ; QL1-991
    Thema/Rubrik (Code) 333
    Sprache Englisch
    Erscheinungsdatum 2023-11-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  7. Artikel ; Online: The Sommerlad pen

    Zeeshan Ahmad

    Indian Journal of Plastic Surgery, Vol 44, Iss 1, Pp 162-

    Yet another use

    2011  Band 163

    Schlagwörter Surgery ; RD1-811 ; Medicine ; R
    Sprache Englisch
    Erscheinungsdatum 2011-01-01T00:00:00Z
    Verlag Medknow Publications
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  8. Artikel ; Online: Detection of C-Reactive Protein Using Histag-HRP Functionalized Nanoconjugate with Signal Amplified Immunoassay

    Mohd Farhan Siddiqui / Zeeshan Ahmad Khan / Seungkyung Park

    Nanomaterials, Vol 10, Iss 1240, p

    2020  Band 1240

    Abstract: Ultrasensitive detection of biomarkers is highly significant for disease prognosis and public health treatment. Despite wide acceptance in routine laboratory tests, the conventional enzyme-linked immunosorbent assay (ELISA) has been of limited use for ... ...

    Abstract Ultrasensitive detection of biomarkers is highly significant for disease prognosis and public health treatment. Despite wide acceptance in routine laboratory tests, the conventional enzyme-linked immunosorbent assay (ELISA) has been of limited use for early biomarker detection due to insufficient sensitivity and multiple long incubation time. Several nanoprobes have been introduced to circumvent the limitation, however, rapid, simple, and chemical-free nanoprobe synthesis and sensitive detection methods, particularly for ELISA, are still lacking. In this study, we have synthesized a gold nanoprobe, conjugated with multiple 6X-histidine (6X-his) peptide and nickel-horseradish peroxidase (Ni 2+ -HRP), for enhancing the colorimetric signal in ELISA. The developed nanoprobe has been tested for the detection of immunologically significant C-reactive protein (CRP) in ELISA format. The performance of designed probe is validated by testing standard and serum samples, and the detection limit of 32.0 pg/mL with R 2 = 0.98 is confirmed. Furthermore, a comparative analysis of the developed nanoprobe was performed with ELISA developed on conventional guidelines, the proposed immunoassay showed an increase of 12-fold sensitivity for detecting CRP due to the high loading of 6Xhis peptide and binding of multiple Ni 2+ -HRP on a gold nanoparticle. Additionally, the proposed assay provides a simple, fast, and cost-efficient (not requiring multiple antibodies) detection of CRP with easy nanoprobe synthesis. Moreover, the developed Histag-HRP functionalized nanoconjugate immunoassay is flexible and can be applied to other biomarkers efficiently by using disease specific antibody.
    Schlagwörter Histag-HRP nanoconjugate ; immunoassay ; C-reactive protein ; ELISA ; biosensor ; Chemistry ; QD1-999
    Thema/Rubrik (Code) 621
    Sprache Englisch
    Erscheinungsdatum 2020-06-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  9. Artikel ; Online: Untying the Precise Impact of COVID-19 Policy on Social Distancing Behavior

    Fakhar Shahzad / Jianguo Du / Imran Khan / Zeeshan Ahmad / Muhammad Shahbaz

    International Journal of Environmental Research and Public Health, Vol 18, Iss 896, p

    2021  Band 896

    Abstract: Social distancing has manifold effects and is used as a non-pharmacological measure to respond to pandemic situations such as the novel coronavirus (COVID-19), especially in the absence of vaccines and other useful antiviral drugs. Governments around the ...

    Abstract Social distancing has manifold effects and is used as a non-pharmacological measure to respond to pandemic situations such as the novel coronavirus (COVID-19), especially in the absence of vaccines and other useful antiviral drugs. Governments around the globe have adopted and implemented a series of social distancing strategies. The efficacy of various policies and their comparative influence on mechanisms led by public actions and adoptions have not been examined. The differences in types and effective dates of various social distancing policies in various provinces/territories of Pakistan constitute a pure ground to examine the causal effects of each COVID-19 policy. Using the location trends and population movement data released by Google, a quasi-experimental method was used to measure the impact of the government’s various social distancing policies on the people’s existence at home and their outside social mobility. Based on the magnitude and importance of policy influences, this research ranked six social distancing policies whose influence exceeded the effect of voluntary behavior. Our research outcomes describe that the trend of staying at home was firmly pushed by state-wide home order rather than necessary business closings and policies that were associated with public gathering restrictions. Strong government policies have a strong causal effect on reducing social interactions.
    Schlagwörter COVID-19 ; social distancing ; healthcare ; policies ; Medicine ; R
    Thema/Rubrik (Code) 300
    Sprache Englisch
    Erscheinungsdatum 2021-01-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
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  10. Artikel: Effect of Daily Coffee Consumption on the Risk of Alzheimer's Disease: A Systematic Review and Meta-Analysis.

    Nila, Irin Sultana / Villagra Moran, Vanina Myuriel / Khan, Zeeshan Ahmad / Hong, Yonggeun

    Journal of lifestyle medicine

    2023  Band 13, Heft 2, Seite(n) 83–89

    Abstract: Alzheimer's disease (AD) is a highly prevalent neurodegenerative disorder that affects millions of individuals globally. The identification of the lifestyle factors that potentially help prevent or postpone disease onset is of interest to the researchers. ...

    Abstract Alzheimer's disease (AD) is a highly prevalent neurodegenerative disorder that affects millions of individuals globally. The identification of the lifestyle factors that potentially help prevent or postpone disease onset is of interest to the researchers. Although the study results are inconsistent, one such factor that has been extensively studied is coffee consumption. Therefore, this meta-analysis primarily aimed to investigate the effects of coffee consumption on the risk of AD. Pubmed, Embase, and Web of Science (Only Writing Web of Science is Fine) databases were searched for relevant studies with the keywords in various combinations, including "coffee", "caffeine", and "Alzheimer's disease". This meta-analysis included 11 studies. The relative risk (RR) with 95% confidence intervals (CI) was calculated to estimate the effect size. The study used the restricted maximum-likelihood method for a generic-inverse-variance analysis with random-effect (when heterogeneity, I
    Sprache Englisch
    Erscheinungsdatum 2023-08-25
    Erscheinungsland Korea (South)
    Dokumenttyp Journal Article ; Review
    ZDB-ID 3021714-3
    ISSN 2288-1557 ; 2234-8549
    ISSN (online) 2288-1557
    ISSN 2234-8549
    DOI 10.15280/jlm.2023.13.2.83
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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