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  1. Artikel ; Online: Characteristics of diagnosed cases with occupational eye diseases in Jiangsu Province from 2013 to 2022

    ZHU Wenjing

    Zhiye weisheng yu yingji jiuyuan (2023)

    2023  

    Schlagwörter occupational eye disease ; occupational cataract ; occupational chemical eye burn ; Medicine ; R
    Sprache Chinesisch
    Erscheinungsdatum 2023-10-01T00:00:00Z
    Verlag Editorial Office of Occupational Health and Emergency Rescue
    Dokumenttyp Artikel ; Online
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  2. Artikel ; Online: Characteristics of reported cases of occupational chemical poisoning in Jiangsu Province from 2013 to 2022

    ZHU Wenjing

    Zhiye weisheng yu yingji jiuyuan (2023)

    2023  

    Schlagwörter Medicine ; R
    Sprache Chinesisch
    Erscheinungsdatum 2023-12-01T00:00:00Z
    Verlag Editorial Office of Occupational Health and Emergency Rescue
    Dokumenttyp Artikel ; Online
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  3. Artikel: Advancements in the diagnosis and management of premature ventricular contractions in pediatric patients.

    Zhu, Wenjing / Yuan, Hui / Lv, Jianli

    Frontiers in pediatrics

    2024  Band 12, Seite(n) 1373772

    Abstract: Background: Premature ventricular contractions (PVCs) are relatively common arrhythmias in the pediatric population, with implications that range from benign to potentially life-threatening. The management of PVCs in children poses unique challenges, ... ...

    Abstract Background: Premature ventricular contractions (PVCs) are relatively common arrhythmias in the pediatric population, with implications that range from benign to potentially life-threatening. The management of PVCs in children poses unique challenges, and recent advancements in diagnostic and therapeutic options call for a comprehensive review of current practices.
    Methods: This review synthesizes the latest literature on pediatric PVCs, focusing on publications from the past decade. We evaluate studies addressing the epidemiology, pathophysiology, diagnosis, and treatment of PVCs in children, including pharmacological, non-pharmacological, and invasive strategies.
    Results: The review identifies key advancements in the non-invasive detection of PVCs, the growing understanding of their genetic underpinnings, and the evolving landscape of management options. We discuss the clinical decision-making process, considering the variable significance of PVCs in different pediatric patient subgroups, and highlight the importance of individualized care. Current guidelines and consensus statements are examined, and areas of controversy or limited evidence are identified.
    Conclusions: Our review underscores the need for a nuanced approach to PVCs in children, integrating the latest diagnostic techniques with a tailored therapeutic strategy. We call for further research into long-term outcomes and the development of risk stratification tools to guide treatment. The potential of emerging technologies and the importance of multidisciplinary care are also emphasized to improve prognoses for pediatric patients with PVCs.
    Sprache Englisch
    Erscheinungsdatum 2024-03-20
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2711999-3
    ISSN 2296-2360
    ISSN 2296-2360
    DOI 10.3389/fped.2024.1373772
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  4. Artikel ; Online: Prevalence of aeroallergen sensitization in children in Northern China.

    Bian, Sainan / Zhu, Wenjing / Guan, Kai / Sha, Li

    The Journal of asthma : official journal of the Association for the Care of Asthma

    2024  , Seite(n) 1–8

    Abstract: Objective: This study aimed to analyze the sensitization rate of different aeroallergens in children of different age, sex, and disease groups, describe the changing trend of different aeroallergens in different ages, and analyze the sensitization risk ... ...

    Abstract Objective: This study aimed to analyze the sensitization rate of different aeroallergens in children of different age, sex, and disease groups, describe the changing trend of different aeroallergens in different ages, and analyze the sensitization risk factors for asthma.
    Methods: Children (<18 years old) with suspected atopic diseases who visited the Department of Allergy of Children's Hospital Affiliated to Capital Institute of Pediatrics and underwent a skin prick test (SPT) were retrospectively enrolled from January 2019 to November 2021.
    Results: A total of 5465 patients (3514 boys, 1951 girls; mean age, 7 ± 3 years) were enrolled. Of them, 3703 patients (67.8%) were sensitized to at least one aeroallergen. Before 4 years of age, mold was the most prevalent aeroallergen (103/380 [27.1%]), whereas after 4 years of age, weed pollen was the most prevalent aeroallergen. After 6 years of age, tree pollen became the second most prevalent aeroallergen. After 12 years of age, the sensitization rate of indoor aeroallergens was lower than that of outdoor aeroallergens. Logistic regression showed that sensitization to mold (odds ratio [OR]:1.4, 95% confidence interval (CI): 1.2-1.7,
    Conclusions: Mold is an important allergen in early life. Different kinds of allergens affect different age groups. Patients who are sensitized to mold or animal dander or experience polysensitization should be carefully monitored for asthma risk.
    Sprache Englisch
    Erscheinungsdatum 2024-03-07
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 603816-5
    ISSN 1532-4303 ; 0277-0903
    ISSN (online) 1532-4303
    ISSN 0277-0903
    DOI 10.1080/02770903.2024.2320783
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  5. Buch ; Online: Determination of the resonant parameters of excited vector strangenia with the $e^{+}e^{-}\to\eta\phi$ data

    Zhu, Wenjing / Wang, XiaoLong

    2023  

    Abstract: We determine the resonant parameters of the vector states $\phi(1680)$ and $\phi(2170)$, by doing a combined fit to the $e^{+}e^{-}\to \eta\phi$ cross sections from threshold to $2.85~\rm GeV$ measured by BaBar, Belle, BESIII and CMD-3 experiments. The ... ...

    Abstract We determine the resonant parameters of the vector states $\phi(1680)$ and $\phi(2170)$, by doing a combined fit to the $e^{+}e^{-}\to \eta\phi$ cross sections from threshold to $2.85~\rm GeV$ measured by BaBar, Belle, BESIII and CMD-3 experiments. The mass $(1678^{+5}_{-3} \pm 7)~\rm MeV/c^2$ and the width $(156\pm 5 \pm 9)~\rm MeV$ are obtained for the $\phi(1680)$, and the mass $(2169\pm 5 \pm 6)~\rm MeV/c^2$ and the width $(96^{+17}_{-14} \pm 9)~\rm MeV$ for the $\phi(2170)$. The statistical significance of $\phi(2170)$ is $7.2\sigma$. Depending on the interference between the $\phi(1680)$, $\phi(2170)$ and a non-resonant $\eta\phi$ amplitude in the nominal fit, we obtain four solutions and $\Gamma^{e^{+}e^{-}}_{\phi(1680)}\cdot \mathcal{B}[\phi(1680)\to\eta\phi] = (79 \pm 4 \pm 16)$, $(127\pm 5 \pm 12)$, $(65^{+5}_{-4} \pm 13)$ or $(215 ^{+8}_{-5} \pm 11)~\rm eV$, and $\Gamma^{e^{+}e^{-}}_{\phi(2170)}\cdot \mathcal{B}[\phi(2170)\to\eta\phi] = (0.56^{+0.03}_{-0.02} \pm 0.07)$, $(0.36^{+0.05}_{-0.03} \pm 0.07)$, $(38 \pm 1 \pm 5)$ or $(41\pm 2 \pm 6)~\rm eV$, respectively. We also search for the production of $X(1750)\to \eta\phi$ and the significance is only $2.0\sigma$, then we determine the upper limit of $\Gamma^{e^{+}e^{-}}_{X(1750)}\cdot \mathcal{B}[X(1750)\to\eta\phi]$ at $90\%$ confidence level.
    Schlagwörter High Energy Physics - Experiment
    Thema/Rubrik (Code) 612
    Erscheinungsdatum 2023-04-17
    Erscheinungsland us
    Dokumenttyp Buch ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  6. Artikel ; Online: Two-Dimensional Cu-Porphyrin Metal-Organic Framework Nanosheet-Supported Flaky TiO

    Zhu, Wenjing / Xia, Zhinan / Shi, Bingfeng / Lü, Changli

    Langmuir : the ACS journal of surfaces and colloids

    2023  Band 39, Heft 44, Seite(n) 15665–15675

    Abstract: A series of 2D M(Cu, Zn, Co, and Mn)-TCPP MOFs/ ... ...

    Abstract A series of 2D M(Cu, Zn, Co, and Mn)-TCPP MOFs/TiO
    Sprache Englisch
    Erscheinungsdatum 2023-10-29
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2005937-1
    ISSN 1520-5827 ; 0743-7463
    ISSN (online) 1520-5827
    ISSN 0743-7463
    DOI 10.1021/acs.langmuir.3c02148
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  7. Artikel ; Online: Modulating multidrug resistance to drug-based antitumor therapies through NF-κB signaling pathway: mechanisms and perspectives.

    Wu, Dapeng / Tian, Sai / Zhu, Wenjing

    Expert opinion on therapeutic targets

    2023  Band 27, Heft 6, Seite(n) 503–515

    Abstract: Introduction: Despite the advances made in cancer treatment in the past decades, therapeutic efficacy is still quite challenging, partially due to the emergence of multidrug resistance (MDR). It is crucial to decipher the underlying mechanisms of ... ...

    Abstract Introduction: Despite the advances made in cancer treatment in the past decades, therapeutic efficacy is still quite challenging, partially due to the emergence of multidrug resistance (MDR). It is crucial to decipher the underlying mechanisms of resistance in order to develop new therapeutic strategies for cancer patients. Previous studies have shown that activation of nuclear factor-κB (NF-κB) plays key roles in various cellular processes including proliferation, anti-apoptosis, metastasis, invasion, and chemoresistance.
    Areas covered: In this review, we conduct an integrated analysis of the evidence suggesting the vital roles of the NF-κB signaling pathway in MDR during chemotherapy, immunotherapy, endocrine, and targeted therapy. A literature search was performed on NF-κB and drug resistance in PubMed up to February 2023.
    Expert opinion: This review summarizes that the NF-κB signaling pathway exhibits a crucial role in enhancing drug resistance in chemotherapy, immunotherapy, endocrine, and targeted therapy. The application of combination therapy with existing antineoplastic drugs and a safe NF-κB inhibitor could become a promising strategy in cancer treatment. A better understanding of the pathway and mechanisms of drug resistance may help exploit safer and more effective NF-κB-targeting agents for clinical use in the future.
    Mesh-Begriff(e) Humans ; NF-kappa B/metabolism ; Signal Transduction ; Antineoplastic Agents/pharmacology ; Neoplasms/drug therapy ; Neoplasms/metabolism ; Drug Resistance, Multiple ; Drug Resistance, Neoplasm ; Cell Line, Tumor
    Chemische Substanzen NF-kappa B ; Antineoplastic Agents
    Sprache Englisch
    Erscheinungsdatum 2023-06-19
    Erscheinungsland England
    Dokumenttyp Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2055208-7
    ISSN 1744-7631 ; 1472-8222
    ISSN (online) 1744-7631
    ISSN 1472-8222
    DOI 10.1080/14728222.2023.2225767
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  8. Artikel ; Online: An improved SIR model describing the epidemic dynamics of the COVID-19 in China.

    Zhu, Wen-Jing / Shen, Shou-Feng

    Results in physics

    2021  Band 25, Seite(n) 104289

    Abstract: In this letter, an improved SIR (ISIR) model is proposed, to analyze the spread of COVID-19 during the time window 21/01/2020-08/02/2021. The parameters can be extracted from an inverse problem of the ISIR to assess the risk of COVID-19. This study ... ...

    Abstract In this letter, an improved SIR (ISIR) model is proposed, to analyze the spread of COVID-19 during the time window 21/01/2020-08/02/2021. The parameters can be extracted from an inverse problem of the ISIR to assess the risk of COVID-19. This study identifies that the cure rate is 0.05 and the reproduction number is 0.4490 during the time interval. The prediction values demonstrates high similarity to the reported data. The results indicate that the disease had been under control in China.
    Sprache Englisch
    Erscheinungsdatum 2021-05-08
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 2631798-9
    ISSN 2211-3797 ; 2211-3797
    ISSN (online) 2211-3797
    ISSN 2211-3797
    DOI 10.1016/j.rinp.2021.104289
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  9. Artikel: Serum levels of specific IgE to cow's milk and its components as predictors of anaphylaxis in Chinese children with cow's milk allergy.

    Qi, Wanting / Chen, Jialing / Zheng, Huishuang / Zhu, Wenjing / Guan, Kai / Sha, Li

    Asian Pacific journal of allergy and immunology

    2024  

    Abstract: Background: Cow's milk allergy (CMA) is one of the most common food allergies in young children. As improved diagnostic tools, allergic tests are inconsistent and limited in predicting anaphylaxis.: Objective: To explore risk factors for anaphylaxis ... ...

    Abstract Background: Cow's milk allergy (CMA) is one of the most common food allergies in young children. As improved diagnostic tools, allergic tests are inconsistent and limited in predicting anaphylaxis.
    Objective: To explore risk factors for anaphylaxis and to determine practical cut-offs for allergic tests in predicting anaphylaxis.
    Methods: This is a prospective cohort study. Children with IgE-mediated CMA were enrolled and divided into three groups (Group 1: non-anaphylaxis; Group 2: GRADE I anaphylaxis; Group 3: GRADE II-IV anaphylaxis that warranted epinephrine). Prick-to-prick tests (PTPs) using fresh cow's milk (CM) were performed. Serum specific IgE (sIgE) against CM and its components, including casein, alpha-lactalbumin, beta-lactoglobulin, and bovine serum albumin were measured. The 90% and 95% positive predictive value (PPV) decision points for predicting anaphylaxis were determined. Potential predictors of anaphylaxis were evaluated in logistic regression models.
    Results: This study included 134 CMA patients with a median age of 14.4 months. The sensitization rate to any CM component was 89%. Group 3 was more likely to be sensitized to multiple CM components and have higher sIgE levels. The 95% PPV diagnostic decision points of casein-sIgE in predicting anaphylaxis was 13.0 kUA/L. For GRADE II-IV anaphylaxis, casein-sIgE ≥ 54.9 kUA/L could provide a PPV of 88.9%. The elevated casein-sIgE level (OR 14.0, P=0.025) and complicating respiratory allergic diseases (OR 4.8, P=0.022) were independent risk factors for GRADE II-IV anaphylaxis.
    Conclusion: High casein-sIgE levels are strongly associated with CM anaphylaxis. Detection of casein-sIgE may offer an additional value for the prediction of CM anaphylaxis.
    Sprache Englisch
    Erscheinungsdatum 2024-01-06
    Erscheinungsland Thailand
    Dokumenttyp Journal Article
    ZDB-ID 605782-2
    ISSN 2228-8694 ; 0125-877X
    ISSN (online) 2228-8694
    ISSN 0125-877X
    DOI 10.12932/AP-010823-1667
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  10. Artikel ; Online: Comparison of Disease Severity, Anxiety and Depression in Obsessive-Compulsive Disorder Patients with Different Insight.

    Zhu, Cheng / Huang, Yueqi / Zhu, Wenjing / Jiang, Xiaoying / Liang, Yan / Tang, Wenxin / Xu, Ziming

    Actas espanolas de psiquiatria

    2024  Band 52, Heft 1, Seite(n) 10–18

    Abstract: Background: Significant individual differences exist in the insight of patients with obsessive-compulsive disorder (OCD), and the clinical characteristics of OCD patients with varying levels of insight are not entirely uniform. This study aims to ... ...

    Abstract Background: Significant individual differences exist in the insight of patients with obsessive-compulsive disorder (OCD), and the clinical characteristics of OCD patients with varying levels of insight are not entirely uniform. This study aims to investigate disparities in disease severity, anxiety, and depression status among OCD patients with differing levels of insight, with the goal of generating novel treatment strategies for OCD.
    Methods: A total of 114 patients diagnosed with OCD were recruited from the Department of Psychology at Affiliated Mental Health Center & Hangzhou Seventh People's Hospital to participate in this research. Based on their Total Insight and Treatment Attitude Questionnaire (ITAQ) scores, the patients were divided into two groups: Group OCD with high insight (referred to as Group OCD-HI, ITAQ score ≥20 points, n = 80) and Group OCD with low insight (referred to as Group OCD-LI, ITAQ score <20 points, n = 34). Subsequently, the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), Hamilton Anxiety Scale (HAMA), and Hamilton Depression Scale (HAMD) scores were compared between the two groups. All questionnaires for this study were completed by experienced psychiatrists.
    Results: The Y-BOCS scores for YB1, YB2, YB4, YB5, YB6, YB9, and the total Y-BOCS scores in Group OCD-HI were significantly higher than those in Group OCD-LI (p < 0.05). Conversely, Group OCD-HI exhibited significantly lower HAMA and HAMD scores compared to Group OCD-LI (p < 0.05). Furthermore, the total ITAQ score displayed a significant negative correlation with the total Y-BOCS, HAMA, and HAMD scores (p < 0.05).
    Conclusions: This study revealed that certain OCD patients exhibit incomplete insight, and this lack of insight is strongly associated with increased disease severity and heightened levels of anxiety and depression. It is hoped that by enhancing the insight of OCD patients, the goal of ameliorating disease symptoms and alleviating negative emotions can be attained.
    Mesh-Begriff(e) Humans ; Depression ; Obsessive-Compulsive Disorder/complications ; Obsessive-Compulsive Disorder/diagnosis ; Anxiety Disorders ; Anxiety ; Patient Acuity
    Sprache Englisch
    Erscheinungsdatum 2024-02-22
    Erscheinungsland Spain
    Dokumenttyp Journal Article
    ZDB-ID 1480971-0
    ISSN 1578-2735 ; 1575-071X ; 1139-9287
    ISSN (online) 1578-2735
    ISSN 1575-071X ; 1139-9287
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