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  1. Artikel ; Online: Current Conditions and Mode of Sustainable Rural Construction

    Wu Xiu / Zhou Pei / Zhu Yixuan / Gong Yulan / He Yanhua

    Redai dili, Vol 43, Iss 2, Pp 268-

    A Case Study of Changsha

    2023  Band 280

    Abstract: Implementing a rural revitalization strategy requires exploring a sustainable rural development path. Promoting sustainable rural construction has become an important issue that urgently needs to be solved. Sustainable countryside is a rural system that ... ...

    Abstract Implementing a rural revitalization strategy requires exploring a sustainable rural development path. Promoting sustainable rural construction has become an important issue that urgently needs to be solved. Sustainable countryside is a rural system that can continuously provide high-quality employment, housing, travel, medical care, education, pensions, communication, and other services for local rural residents. It can also continuously provide healthy agricultural products, good ecological products, and cultural tourism experiences for surrounding residents, including sustainable rural industry, sustainable rural environment, and sustainable farmers' lives. Sustainable rural construction is the goal and vision of the implementation for the rural revitalization strategy. This is conducive to solving the issues related to agriculture, rural areas, and rural people, narrowing the gap between urban and rural areas, and promoting the integration of urban and rural development. In recent years, rural revitalization work in Changsha (the capital city of Hunan Province) has been at the forefront of Hunan Province. In 2020, the total output value of agriculture, forestry, animal husbandry, and fishery in the city was 72,219.25 million yuan; the per capita disposable income of rural areas was 34,754.3 yuan, which is 18,169.7 yuan higher than the average level of the whole province; and the income ratio of urban and rural residents was 1.7, which is 0.8 lower than the average level of Hunan Province. Rural infrastructure and public services have been significantly improved, but at the same time, there are also many problems. Based on this, guided by the theory of sustainable development and the theory of the hierarchy of needs, this paper explains the connotation and system composition of sustainable villages in detail. Beginning with the elements of a sustainable rural system, this paper analyzes the common problems and individual characteristics faced by the sustainable development of rural areas in Changsha by means ...
    Schlagwörter sustainable countryside ; rural system ; rural construction ; rural optimization model ; changsha city ; Geography (General) ; G1-922
    Thema/Rubrik (Code) 910
    Sprache Chinesisch
    Erscheinungsdatum 2023-02-01T00:00:00Z
    Verlag Editorial Committee of Tropical Geography
    Dokumenttyp Artikel ; Online
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  2. Artikel ; Online: Risk of Overweight and Obesity in Children and Adolescents With Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-Analysis.

    Zhu, Yixuan / Wang, Nian-Nian / Pan, Da / Wang, Shaokang

    Childhood obesity (Print)

    2023  Band 20, Heft 2, Seite(n) 119–127

    Abstract: This study was performed to explore the association between attention-deficit/hyperactivity disorder (ADHD) and the risk of overweight/obesity in both children and adolescents. The PubMed, Web of Science, and Cochrane Library databases were searched for ... ...

    Abstract This study was performed to explore the association between attention-deficit/hyperactivity disorder (ADHD) and the risk of overweight/obesity in both children and adolescents. The PubMed, Web of Science, and Cochrane Library databases were searched for relevant studies published before July 12, 2022. Studies with data for calculating the odds ratio (OR) of childhood overweight/obesity and ADHD were included. The literature value was assessed by the cross-sectional evaluation criteria proposed by the Agency for Healthcare Research and Quality (AHRQ). All analyses were conducted using StataSE 11 and RevMan 5.3 software with random-effects models. This review included a total of 16 studies covering 14,981 cases and 128,916 controls.According to the meta-analysis, children with ADHD had a significant risk for co-occurring overweight and obesity [OR 1.56; 95% confidence intervals (CI) 1.32-1.85], especially boys (OR 1.45; 95% CI 1.10-1.90), people in Asia (OR 3.25; 95% CI 1.70-6.21) and Europe (OR 1.85; 95% CI 1.61-2.12), and patients not using medication (OR 1.54; 95% CI 1.22-1.94).ADHD has a significant association with overweight and obesity in both children and adolescents, which may be altered by factors such as geography, gender, and medication use. Timely treatment should be provided to children and adolescents diagnosed with ADHD to inhibit the emergence of overweight and obesity.
    Mesh-Begriff(e) Adolescent ; Child ; Humans ; Attention Deficit Disorder with Hyperactivity/complications ; Attention Deficit Disorder with Hyperactivity/epidemiology ; Cross-Sectional Studies ; Databases, Factual ; Overweight/complications ; Overweight/epidemiology ; Pediatric Obesity/complications ; Pediatric Obesity/epidemiology ; United States/epidemiology
    Sprache Englisch
    Erscheinungsdatum 2023-03-23
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 2639910-6
    ISSN 2153-2176 ; 2153-2168
    ISSN (online) 2153-2176
    ISSN 2153-2168
    DOI 10.1089/chi.2022.0230
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Identification of rural settlement development types in the farming-pastoral zone based on social network analysis

    ZOU Yafeng / LUO Feng / RAO Yufei / ZHU Yixuan / YI Chengfeng / LV Changhe / WU Pinqi

    Ziyuan Kexue, Vol 45, Iss 11, Pp 2222-

    2023  Band 2233

    Abstract: Objective] The classification of rural settlement development types is crucial for comprehensive and effective village planning. By examining the characteristics of rural resident travel behaviors, this study aimed to categorize rural settlement ... ...

    Abstract [Objective] The classification of rural settlement development types is crucial for comprehensive and effective village planning. By examining the characteristics of rural resident travel behaviors, this study aimed to categorize rural settlement development types and subsequently propose tailored strategies for rural revitalization. This approach can significantly contribute to the sustainable and holistic development of rural areas. [Methods] This study applied social network analysis to examine the spatial linkage patterns of rural resident travel behaviors in Kekeyiligeng (Ke Town) of Wuchuan County. It also incorporated expert scoring to obtain the weights of various travel frequencies. Subsequently, it used kernel density estimation to study the spatial distribution characteristics of rural settlements within the research area. By measuring the intensity and degree of centrality of these rural settlements, the study was able to identify their development types using the general matrix model. Finally, this study proposed paths of rural revitalization tailored to the specific development types, to foster sustainable growth and development in the region. [Results] The research results show that: (1) Among the daily travel activities of Ke Town residents, socializing comprises the largest share (52%), followed by shopping (26%) and studying (13%), while medical care and work account for similar proportions (4%), and tourism has the smallest share (1%). (2) The connection strength between settlements within Ke Town forms a network structure emanating from the central node represented by the central town. Key factors influencing connection strength include transportation infrastructure, resource endowment, and population size. Settlements with high degree centrality are typically located along transportation routes or in close proximity to the central town. (3) Ke Town’s rural settlements are categorized into five types: suburban integration (20), characteristic protection (9), agglomeration promotion (44), ...
    Schlagwörter |rural revitalization|social network analysis|type identification|farming-pastoral zone|ke town of wuchuan county ; Environmental sciences ; GE1-350 ; Biology (General) ; QH301-705.5
    Thema/Rubrik (Code) 910
    Sprache Chinesisch
    Erscheinungsdatum 2023-11-01T00:00:00Z
    Verlag Science Press, PR China
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  4. Artikel ; Online: Targeted Integration of Complex Genetic Elements at Multi-Copy Loci by Golden Gate Assembly.

    Zhu, Yixuan / Cao, Limin

    Methods in molecular biology (Clifton, N.J.)

    2020  Band 2196, Seite(n) 143–151

    Abstract: Budding yeast Saccharomyces cerevisiae has become a model eukaryotic microorganism for targeted genomic manipulation due to its efficient homologous recombination. A few genomic loci, including rDNA, Delta, and Ty1, can be utilized to introduce variable ... ...

    Abstract Budding yeast Saccharomyces cerevisiae has become a model eukaryotic microorganism for targeted genomic manipulation due to its efficient homologous recombination. A few genomic loci, including rDNA, Delta, and Ty1, can be utilized to introduce variable copies of genetic elements into the yeast genome. Here we describe a method that combines in vitro Golden Gate Assembly to assemble one or a complex genetic element in an orderly manner and then integrate it into predetermined multi-copy loci through homologous recombination. Different transformants may contain different copy numbers, which allows the selection of desired levels of target gene expression.
    Mesh-Begriff(e) Cloning, Molecular ; Gene Dosage ; Gene Targeting ; Genetic Loci ; Genetic Vectors/genetics ; Mutagenesis, Site-Directed ; Recombination, Genetic ; Repetitive Sequences, Nucleic Acid ; Saccharomyces cerevisiae/genetics ; Transformation, Genetic
    Sprache Englisch
    Erscheinungsdatum 2020-09-05
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-0868-5_11
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Buch ; Online: Scope and Arbitration in Machine Learning Clinical EEG Classification

    Zhu, Yixuan / Canham, Luke J. W. / Western, David

    2023  

    Abstract: A key task in clinical EEG interpretation is to classify a recording or session as normal or abnormal. In machine learning approaches to this task, recordings are typically divided into shorter windows for practical reasons, and these windows inherit the ...

    Abstract A key task in clinical EEG interpretation is to classify a recording or session as normal or abnormal. In machine learning approaches to this task, recordings are typically divided into shorter windows for practical reasons, and these windows inherit the label of their parent recording. We hypothesised that window labels derived in this manner can be misleading for example, windows without evident abnormalities can be labelled `abnormal' disrupting the learning process and degrading performance. We explored two separable approaches to mitigate this problem: increasing the window length and introducing a second-stage model to arbitrate between the window-specific predictions within a recording. Evaluating these methods on the Temple University Hospital Abnormal EEG Corpus, we significantly improved state-of-the-art average accuracy from 89.8 percent to 93.3 percent. This result defies previous estimates of the upper limit for performance on this dataset and represents a major step towards clinical translation of machine learning approaches to this problem.

    Comment: 10 pages, 6 figures
    Schlagwörter Computer Science - Machine Learning
    Thema/Rubrik (Code) 006
    Erscheinungsdatum 2023-03-11
    Erscheinungsland us
    Dokumenttyp Buch ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  6. Artikel ; Online: Fluid transport in porous media based on differences in filter media morphology and biofilm growth in bioreactors

    Tang, Ping / Xu, Henglei / Zhang, Wenming / Zhu, Yixuan / Yang, Jin / Zhou, Yongchao

    Environmental Research. 2023 Feb., v. 219 p.115122-

    2023  

    Abstract: To elucidate the effect of pore structure on bioclogging and seepage flow in bioreactors, we used X-ray computed tomography (X-CT) to investigate the changes in seepage flow of porous media in zeolite, gravel and ceramsite bioreactors with biofilm growth ...

    Abstract To elucidate the effect of pore structure on bioclogging and seepage flow in bioreactors, we used X-ray computed tomography (X-CT) to investigate the changes in seepage flow of porous media in zeolite, gravel and ceramsite bioreactors with biofilm growth by injecting a non-ionic contrast medium iohexol. Based on the X-CT images using a ball-and-stick model, the highest average pore radius (R‾) and the average pore throat radius (r‾) in the ceramsite column were found under the initial conditions, which facilitated its permeability. The pore and throat of the gravel column were small and homogeneous relatively. Biofilm growth decreased the pore and pore throat in the columns. The total throat area of zeolite, gravel and ceramsite columns declined by 74%, 73% and 79% respectively. The zeolite column had the highest average pore throat, which contributed to its maximum conductivity subsequently after biofilm growth. Further, the fractal dimensions of the pore structure increased with biofilm growth, especially in the zeolite and ceramsite columns. The heterogeneity of the porous media was reinforced by the biofilm growth in the zeolite and ceramsite columns due to their higher heterogeneity initially. We also observed that an increase in heterogeneity of porous medium amplified the preferential flow and flow heterogeneities, especially in the zeolite and ceramsite columns.
    Schlagwörter X-radiation ; biofilm ; bioreactors ; gravel ; models ; permeability ; porous media ; preferential flow ; research ; seepage ; throat ; tomography ; zeolites ; Bioclogging ; Hydraulic conductivity ; Pore scale heterogeneity
    Sprache Englisch
    Erscheinungsverlauf 2023-02
    Erscheinungsort Elsevier Inc.
    Dokumenttyp Artikel ; Online
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2022.115122
    Datenquelle NAL Katalog (AGRICOLA)

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  7. Artikel ; Online: Cuscuta chinensis flavonoids reducing oxidative stress of the improve sperm damage in bisphenol A exposed mice offspring.

    Zhao, Qianhui / Liu, Ying / Wang, Xiao / Zhu, Yixuan / Jiao, Yulan / Bao, Yongzhan / Shi, Wanyu

    Ecotoxicology and environmental safety

    2023  Band 255, Seite(n) 114831

    Abstract: Bisphenol A (BPA) is a common environmental endocrine disruptor, and overexposure is a threat to male reproduction. Although studies have confirmed that BPA exposure causes a decrease in sperm quality in offspring, the dosage used, and the underlying ... ...

    Abstract Bisphenol A (BPA) is a common environmental endocrine disruptor, and overexposure is a threat to male reproduction. Although studies have confirmed that BPA exposure causes a decrease in sperm quality in offspring, the dosage used, and the underlying mechanism is not clear. The purpose of this study is to investigate whether Cuscuta chinensis flavonoids (CCFs) can antagonize or alleviate BPA-induced reproductive injury by analyzing the processes associated with BPA's impairment of sperm quality. BPA and 40 mg/kg bw/day of CCFs were administered to the dams at gestation day (GD) 0.5-17.5. Testicles and serum of male mice are collected on postnatal day 56 (PND56), and spermatozoa are collected to detect relevant indicators. Our results showed that compared with the BPA group, CCFs could significantly increase the serum contents of luteinizing hormone (LH), follicle-stimulating hormone (FSH), and testosterone (T) in males at PND 56, as well as the transcription levels of estrogen receptor alpha (ERα), steroidogenic acute regulatory protein (StAR) and Cytochrome P450 family 11, subfamily A, and member 1 (CYP11A1). CCFs also significantly inhibit the production of reactive oxygen species (ROS), reduce oxidative stress, increase mitochondrial membrane potential, and reduce sperm apoptosis. It also has a certain regulatory effect on sperm telomere length and mitochondrial DNA copy number. These results suggest that CCFs can increase reproductive hormone and receptor levels in adult males by regulating the expression of oxidative stress correlated factors, and ultimately mitigate the negative effects of BPA on sperm quality in male mice.
    Mesh-Begriff(e) Mice ; Male ; Animals ; Cuscuta ; Flavonoids/pharmacology ; Flavonoids/metabolism ; Seeds ; Spermatozoa ; Testis ; Benzhydryl Compounds/metabolism ; Testosterone ; Oxidative Stress
    Chemische Substanzen bisphenol A (MLT3645I99) ; Flavonoids ; Benzhydryl Compounds ; Testosterone (3XMK78S47O)
    Sprache Englisch
    Erscheinungsdatum 2023-03-24
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 436536-7
    ISSN 1090-2414 ; 0147-6513
    ISSN (online) 1090-2414
    ISSN 0147-6513
    DOI 10.1016/j.ecoenv.2023.114831
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  8. Artikel ; Online: Complete chloroplast genome sequences of two species used for Tibetan medicines,

    Zhu, Yixuan / Zhang, Dequan

    Mitochondrial DNA. Part B, Resources

    2019  Band 5, Heft 1, Seite(n) 48–50

    Abstract: ... ...

    Abstract Meconopsis
    Sprache Englisch
    Erscheinungsdatum 2019-12-11
    Erscheinungsland England
    Dokumenttyp Journal Article
    ISSN 2380-2359
    ISSN (online) 2380-2359
    DOI 10.1080/23802359.2019.1693918
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  9. Artikel ; Online: Simultaneous Electrical and Mechanical Characterization of Single-Molecule Junctions Using AFM-BJ Technique.

    Zhu, Yixuan / Tan, Zhibing / Hong, Wenjing

    ACS omega

    2021  Band 6, Heft 46, Seite(n) 30873–30888

    Abstract: The fabrication and characterization of single-molecule junctions provide a unique platform to study the physical phenomena of a single molecule, and the electrical characterization enables us to understand the electrical transport properties of a single ...

    Abstract The fabrication and characterization of single-molecule junctions provide a unique platform to study the physical phenomena of a single molecule, and the electrical characterization enables us to understand the electrical transport properties of a single molecule and guide the fabrication of molecular electronic devices. However, the electrical characterization of single-molecule junctions is sometimes insufficient to extract the structural information on single-molecule junctions, and an alternate method to address this problem is to characterize the mechanical properties of single-molecule junctions. Simultaneous measurement of mechanical and electrical properties can provide complementary information on single molecules to analyze the correlations of their electrical and mechanical properties in the evolution of single-molecule junctions. In this mini-review, we summarize the progress on the simultaneous characterizations of mechanical and electrical properties for single-molecule junctions, and discuss the challenges and perspectives of this research area.
    Sprache Englisch
    Erscheinungsdatum 2021-11-12
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.1c04785
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  10. Artikel ; Online: Current research insights into the role of CTLA-4 in hepatitis B virus (HBV) infection.

    Gu, Qi / Yin, Shengxia / Tong, Xin / Rui, Fajuan / Zhu, Yixuan / Ma, Xiaoyan / Huang, Rui / Wu, Chao / Li, Jie

    Journal of viral hepatitis

    2024  

    Abstract: Chronic hepatitis B virus (HBV) infection is a significant global public health concern, and the clearance of HBV is closely linked to the activity of HBV-specific T cells, which is regulated by various co-suppressor molecules. Cytotoxic T lymphocyte- ... ...

    Abstract Chronic hepatitis B virus (HBV) infection is a significant global public health concern, and the clearance of HBV is closely linked to the activity of HBV-specific T cells, which is regulated by various co-suppressor molecules. Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) is among these co-suppressor molecules which induces T cell exhaustion by competitively inhibiting CD28 and dampening the function of HBV-specific T cells. CTLA-4 also plays a role in the regulation of T helper (Th) cell differentiation and influences cytokine release. In addition, CTLA-4 can impact glucose metabolism in hepatocellular carcinoma through its interaction with T regulatory (Treg) cells. This review aims to provide a comprehensive overview of the existing literature related to the role of CTLA-4 in HBV patients across different subsets of T cells. Additionally, we propose a discussion on the possible mechanisms through which CTLA-4 may contribute to HBV infection, as well as the development of HBV-induced cirrhosis and hepatocellular carcinoma.
    Sprache Englisch
    Erscheinungsdatum 2024-05-21
    Erscheinungsland England
    Dokumenttyp Journal Article ; Review
    ZDB-ID 1212497-7
    ISSN 1365-2893 ; 1352-0504
    ISSN (online) 1365-2893
    ISSN 1352-0504
    DOI 10.1111/jvh.13958
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