Article ; Online: Effect of dietary advanced glycation end-products restriction on type 2 diabetes mellitus control: a systematic review.
2021 Volume 80, Issue 2, Page(s) 294–305
Abstract: Context: Reducing dietary advanced glycation end-products (AGEs) may favor diabetes control.: Objective: Critically analyze studies about the effect of dietary AGEs restriction on inflammation, oxidative stress, and glycemic control in patients with ... ...
| Abstract | Context: Reducing dietary advanced glycation end-products (AGEs) may favor diabetes control. Objective: Critically analyze studies about the effect of dietary AGEs restriction on inflammation, oxidative stress, and glycemic control in patients with type 2 diabetes mellitus (DM2). Data source: This systematic review was conducted according to PRISMA methodology. The PubMed, Web of Science, LILACS, and Cochrane Library databases were searched, using the terms "type 2 diabetes," "advanced glycation end products" and "diet." Data extraction: Seven original studies were included in this review. The duration of the studies ranged from 1 day to 16 weeks. All extracted data were compiled, compared, and critically analyzed. Data analysis: Glycemic variables were considered the primary outcomes. The secondary outcomes were glycation, inflammatory, and oxidative stress markers. Conclusion: Although serum insulin, homeostasis model assessment of insulin resistance, and glycated hemoglobin values were lower after the consumption of AGEs restricted diets in most studies, there was a lack of unanimity regarding dietary AGEs' positive effect on inflammation, oxidative stress, and blood glucose. Systematic review registration: PROSPERO registration no. CRD42020152640. |
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| MeSH term(s) | Blood Glucose ; Diabetes Mellitus, Type 2 ; Glycated Hemoglobin A ; Glycation End Products, Advanced ; Humans ; Insulin Resistance | |||||
| Chemical Substances | Blood Glucose ; Glycated Hemoglobin A ; Glycation End Products, Advanced | |||||
| Language | English | |||||
| Publishing date | 2021-05-19 | |||||
| Publishing country | United States | |||||
| Document type | Journal Article ; Research Support, Non-U.S. Gov't ; Systematic Review | |||||
| ZDB-ID | 82067-2 | |||||
| ISSN | 1753-4887 ; 0029-6643 | |||||
| ISSN (online) | 1753-4887 | |||||
| ISSN | 0029-6643 | |||||
| DOI | 10.1093/nutrit/nuab020 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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